Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging

Dry Gel Containing Optimized Felodipine-Loaded Transferosomes: a Promising Transdermal Delivery System to Enhance Drug Bioavailability

(2018) Mohammed Ali Kassem et al.   AAPS PHARMSCITECH

Potential of Near-Infrared Chemical Imaging as Process Analytical Technology Tool for Continuous Freeze-Drying

(2018) Davinia Brouckaert et al.   ANALYTICAL CHEMISTRY

DPPC Bilayers in Solutions of High Sucrose Content

(2018) Mattia I. Morandi et al.   BIOPHYSICAL JOURNAL

Hyaluronan-decorated liposomes as drug delivery systems for cutaneous administration

(2018) Silvia Franzé et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effect of hydroxypropyl-β–cyclodextrin on lipid membrane fluidity, stability and freeze-drying of liposomes

(2018) Riham Gharib et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Molecular view of the structural reorganization of water in DPPC multilamellar membranes induced by l -cysteine methyl ester

(2018) Juan Marcelo Arias et al.   JOURNAL OF MOLECULAR STRUCTURE

Factors Influencing the Retention of Organic Solvents in Products Freeze-Dried From Co-Solvent Systems

(2018) Claudia Kunz et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Formulation Optimization of Freeze-Dried Long-Circulating Liposomes and In-Line Monitoring of the Freeze-Drying Process Using an NIR Spectroscopy Tool

(2018) Bianca Sylvester et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Use of nanoparticle concentration as a tool to understand the structural properties of colloids

(2018) Lígia Nunes de Morais Ribeiro et al.   Scientific Reports

Mucoadhesive Interpolyelectrolyte Complexes for the Buccal Delivery of Clobetasol

(2018) Venera Garipova et al.   Polymers

Development of a solid dosage platform for the oral delivery of bilayer vesicles

(2017) Jitinder S. Wilkhu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The care and feeding of a commercial liposomal product: liposomal amphotericin B (AmBisome®)

(2017) Gerard M. Jensen   JOURNAL OF LIPOSOME RESEARCH

Lyophilized Drug Product Cake Appearance: What Is Acceptable?

(2017) Sajal Manubhai Patel et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A quality by design approach for the development of lyophilized liposomes with simvastatin

(2017) Alina Porfire et al.   SAUDI PHARMACEUTICAL JOURNAL

Practical Considerations for Determination of Glass Transition Temperature of a Maximally Freeze Concentrated Solution

(2016) Swapnil K. Pansare et al.   AAPS PHARMSCITECH

Effects of flavonol glycosides on liposome stability during freezing and drying

(2016) Antoaneta V. Popova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Formulation and in vitro efficacy of liposomes containing the Hsp90 inhibitor 6BrCaQ in prostate cancer cells

(2016) Félix Sauvage et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Using Texture Analysis Technique to Assess the Freeze-Dried Cakes in Vials

(2016) Ellen V. Hackl et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Lyophilized protein powders: A review of analytical tools for root cause analysis of lot-to-lot variability

(2016) Verena Wahl et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Solidification of liposomes by freeze-drying: The importance of incorporating gelatin as interior support on enhanced physical stability

(2015) Peipei Guan et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Enhanced stability of liposomes against solidification stress during freeze-drying and spray-drying by coating with calcium alginate

(2015) Lijuan Wang et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Thermotropic Phase Behavior of Hydrogenated Soybean Phosphatidylcholine–Cholesterol Binary Liposome Membrane

(2014) Hiroki Kitayama et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Effect of sucrose as a lyoprotectant on the integrity of paclitaxel-loaded liposomes during lyophilization

(2014) Vinayagam Kannan et al.   JOURNAL OF LIPOSOME RESEARCH

QbD approach to investigate product and process variabilities for brain targeting liposomes

(2014) Nahid Kamal et al.   JOURNAL OF LIPOSOME RESEARCH

Long-Term Storage of Lyophilized Liposomal Formulations

(2014) Nicole M. Payton et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Enhanced hydration stability ofBombyx morisilk fibroin/PEG 600 composite scaffolds for tissue engineering

(2014) Francesca Selmin et al.   POLYMERS FOR ADVANCED TECHNOLOGIES

FTIR spectroscopy study of the pressure-dependent behaviour of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1-palmitoyl-2-oleolyl-sn-glycero-3-phosphocholine (POPC) at low degrees of hydration

(2013) H. Pfeiffer et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Hyaluronic acid-coated liposomes for active targeting of gemcitabine

(2013) Silvia Arpicco et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Accurate Prediction of Collapse Temperature using Optical Coherence Tomography-Based Freeze-Drying Microscopy

(2013) Kristyn Greco et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Morphological and Compressional Mechanical Properties of Freeze-Dried Mannitol, Sucrose, and Trehalose Cakes

(2013) Sharmila Devi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Review on Freeze Drying of Drugs withtert-Butanol (TBA) + Water Systems: Characteristics, Advantages, Drawbacks

(2012) Séverine Vessot et al.   DRYING TECHNOLOGY

Cyclodextrin as membrane protectant in spray-drying and freeze-drying of PEGylated liposomes

(2012) Jolanda M. van den Hoven et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Physico-chemical characterisation of cationic DOTAP liposomes as drug delivery system for a hydrophilic decapeptide before and after freeze-drying

(2011) Alena Wieber et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Stabilization of liposomes during drying

(2011) Pall Thor Ingvarsson et al.   Expert Opinion on Drug Delivery

Characterization of a liposome-based formulation of oxaliplatin using capillary electrophoresis: Encapsulation and leakage

(2011) Ulrik Franzen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Investigation of PEG Crystallization in Frozen and Freeze‐Dried PEGylated Recombinant Human Growth Hormone–Sucrose Systems: Implications on Storage Stability

(2011) Bakul S. Bhatnagar et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Stabilization of Liposomes in Frozen Solutions Through Control of Osmotic Flow and Internal Solution Freezing by Trehalose

(2011) Ken-Ichi Izutsu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Freeze-drying of ATP entrapped in cationic, low lipid liposomes

(2010) Véronique Vincourt et al.   CRYOBIOLOGY

Long-term stability of sterically stabilized liposomes by freezing and freeze-drying: Effects of cryoprotectants on structure

(2010) Brigitte Stark et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Preparation of liposomes containing zedoary turmeric oil using freeze-drying of liposomes via TBA/water cosolvent systems and evaluation of the bioavailability of the oil

(2010) Zhiwen Yang et al.   JOURNAL OF DRUG TARGETING

Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates

(2010) Vasco Filipe et al.   PHARMACEUTICAL RESEARCH

Recent advances in liposomal dry powder formulations: preparation and evaluation

(2009) Ambikanandan Misra et al.   Expert Opinion on Drug Delivery

An overview of liposome lyophilization and its future potential

(2009) Chengjun Chen et al.   JOURNAL OF CONTROLLED RELEASE

Structural effects caused by spray‐ and freeze‐drying of liposomes and bilayer disks

(2009) Per Wessman et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The inverse hexagonal – inverse ribbon – lamellar gel phase transition sequence in low hydration DOPC:DOPE phospholipid mixtures

(2008) Ben Kent et al.   CHEMISTRY AND PHYSICS OF LIPIDS