Cell Migration and Invasion Assays as Tools for Drug Discovery

Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis

(2010) Pamela Zengel et al.   BMC CANCER

Expression of neuregulin 4 splice variants in normal human tissues and prostate cancer and their effects on cell motility

(2010) N. V. L. Hayes et al.   ENDOCRINE-RELATED CANCER

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells

(2010) Samir Attoub et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma

(2010) Seung-Oe Lim et al.   FEBS LETTERS

Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma

(2010) Lu Jiang et al.   INTERNATIONAL JOURNAL OF CANCER

A critical analysis of current in vitro and in vivo angiogenesis assays

(2010) Carolyn A. Staton et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

(2010) Rebecca W. Scott et al.   JOURNAL OF CELL BIOLOGY

PAI-1 Mediates the TGF-β1+EGF-Induced “Scatter” Response in Transformed Human Keratinocytes

(2010) Jennifer Freytag et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A novel asymmetric 3D in-vitro assay for the study of tumor cell invasion

(2009) Vera Brekhman et al.   BMC CANCER

Applications of High Content Screening in Life Science Research

(2009) Joseph Zock   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Anthocyanins from black soybean seed coats stimulate wound healing in fibroblasts and keratinocytes and prevent inflammation in endothelial cells

(2009) Irina Tsoy Nizamutdinova et al.   FOOD AND CHEMICAL TOXICOLOGY

The third type III module of human fibronectin mediates cell adhesion and migration

(2009) M. Obara et al.   JOURNAL OF BIOCHEMISTRY

Cell Culture Models in Microfluidic Systems

(2008) Ivar Meyvantsson et al.   Annual Review of Analytical Chemistry

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL

A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro

(2008) Yoonseok Kam et al.   BMC CANCER

Profiling distinct mechanisms of tumour invasion for drug discovery: imaging adhesion, signalling and matrix turnover

(2008) Neil O. Carragher   CLINICAL & EXPERIMENTAL METASTASIS

3D cell culture opens new dimensions in cell-based assays

(2008) Bradley A. Justice et al.   DRUG DISCOVERY TODAY

Protein Kinase C-ϵ Regulates Sphingosine 1-Phosphate-mediated Migration of Human Lung Endothelial Cells through Activation of Phospholipase D2, Protein Kinase C-ζ, and Rac1

(2008) Irina Gorshkova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

Identification of genes that regulate epithelial cell migration using an siRNA screening approach

(2008) Kaylene J. Simpson et al.   NATURE CELL BIOLOGY

PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing

(2008) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION

Evaluating Drug Efficacy and Toxicology in Three Dimensions: Using Synthetic Extracellular Matrices in Drug Discovery

(2007) Glenn D. Prestwich   ACCOUNTS OF CHEMICAL RESEARCH