Article
Clinical Neurology
Elaine M. Boland, Jennifer R. Goldschmied, Philip R. Gehrman
Summary: Rates of major depressive disorder (MDD) are increasing globally, and insomnia treatment may play a preventive role in reducing the risk of MDD onset. This systematic review evaluated the current evidence for the effects of cognitive behavioral treatment for insomnia (CBT-I) on preventing depression onset. Six studies were included, and the majority found lower rates of MDD onset in those who received CBT-I. However, methodological heterogeneity across the studies limits the ability to draw firm conclusions.
Article
Clinical Neurology
Jennifer Duffecy, Rebecca Grekin, Jeffrey D. Long, James A. Mills, Michael O'Hara
Summary: This study evaluated the effectiveness of the internet-based cognitive-behavioral intervention Sunnyside in preventing postpartum depression (PPD) in group and individual formats. The results showed no significant differences between the group and individual interventions in terms of depression and anxiety outcomes, but participants in the individual condition reported higher satisfaction. Despite limitations such as a predominantly white sample and online recruitment, the study provided evidence for the effectiveness of online preventive interventions in improving postpartum mood symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Jennifer N. Felder, Elissa S. Epel, John Neuhaus, Andrew D. Krystal, Aric A. Prather
Summary: The study examines the effects of digital cognitive behavior therapy for insomnia (dCBT-I) during pregnancy on subjective sleep outcomes, depressive symptoms, and anxiety symptoms. The findings suggest that dCBT-I can improve postpartum insomnia remission rates and reduce the incidence of insomnia. Additionally, dCBT-I shows significant improvements in depressive and anxiety symptom severity, particularly among patients with minimal depressive symptoms at baseline.
Article
Psychiatry
Jiaqi Song, Ronghuan Jiang, Nan Chen, Wei Qu, Dan Liu, Meng Zhang, Hongzhen Fan, Yanli Zhao, Shuping Tan
Summary: This study investigated the efficacy of a mobile application in addressing psychological problems related to COVID-19 among Chinese participants with depression symptoms. The results showed that mobile internet cognitive behavioral therapy sessions significantly improved depression and insomnia symptoms, compared to the wait-list group. The participants found the mobile application helpful and enjoyable in relieving depression and insomnia during the COVID-19 outbreak.
ASIAN JOURNAL OF PSYCHIATRY
(2021)
Article
Psychology, Clinical
Christian S. Chan, Christy Y. F. Wong, Branda Y. M. Yu, Victoria K. Y. Hui, Fiona Y. Y. Ho, Pim Cuijpers
Summary: This study evaluated the efficacy of a self-help smartphone-based CBT-I in alleviating major depression and insomnia. The results showed that participants in the treatment group had significantly lower levels of depression, insomnia, anxiety, and better sleep quality compared to the waitlist control group.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Clinical Neurology
Ricardo Tavares Pinheiro, Jessica Puchalski Trettim, Mariana Bonati de Matos, Karen Amaral Tavares Pinheiro, Ricardo Azevedo da Silva, Clarissa Ribeiro Martins, Gabriela Kurz da Cunha, Fernanda Teixeira Coelho, Janaina Vieira dos Santos Motta, Fabio Monteiro da Cunha Coelho, Gabriele Ghisleni, Fernanda Nedel, Ana Paula Ardais, Rafaelle Stark Stigger, Luciana de Avila Quevedo, Luciano Dias de Mattos Souza
Summary: This study evaluated the effectiveness of preventive cognitive behavioral therapy for postpartum depression (PPD). The results showed that a brief cognitive behavioral therapy conducted by mental health professionals with basic training was effective in preventing the manifestation of PPD. Education level was identified as a factor associated with both the manifestation of PPD and the effectiveness of the therapy.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Behavioral Sciences
Lampros Bisdounis, Kate E. A. Saunders, Hannah J. Farley, Charlotte K. Lee, Niall M. McGowan, Colin A. Espie, Simon D. Kyle
Summary: This review evaluates the effectiveness of psychological and behavioral interventions that target sleep and circadian rhythms in bipolar disorder (BD) and finds limited evidence and lack of consistency in protocols and outcomes for these interventions.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Clinical Neurology
Martin Kraepelien, Erik Forsell, Kerstin Blom
Summary: This study aimed to compare comorbidity and patient characteristics before and after the implementation of CBT-I for patients receiving treatment for depression. While pretreatment symptom levels were high, there were no significant changes in insomnia severity or comorbid diagnosis after CBT-I implementation. Contrary to expectations, comorbid depression levels among insomnia patients having CBT-I remained similar to previous studies.
JOURNAL OF SLEEP RESEARCH
(2022)
Review
Multidisciplinary Sciences
Wenyao Lin, Na Li, Lili Yang, Yuqing Zhang
Summary: This meta-analysis found that digitally-delivered cognitive behavioral therapy for insomnia (dCBT-I) seems to be effective in alleviating insomnia and depression.
Article
Dermatology
Melissa Butt, Andrea Rigby, Douglas L. Leslie, Galen T. Foulke, Alexandra Flamm, Joslyn S. Kirby, Vernon M. Chinchilli
Summary: This cross-sectional study found that internalized skin bias was associated with adverse psychopathology and impaired health-related quality of life in patients with hidradenitis suppurativa. Furthermore, internalized skin bias appears to mediate the associations of depression and anxiety with health-related quality of life.
Article
Clinical Neurology
Philipp Hurlimann, Guy Bodenmann, Dieter Riemann, Katharina Weitkamp
Summary: This study aimed to assess the effectiveness of two cognitive behavioural therapy-based online courses, stressfit for stress management and SweetDreams for insomnia, through a randomized trial. The courses provided psychoeducation and strategies for stress, sleep, and insomnia, as well as exercises and evidence-based methods to increase self-efficacy. The results showed significant positive effects of both courses compared to the wait list condition, including improvements in insomnia symptoms, wellbeing, life satisfaction, general health, and coping with stress and sleep disorders at both 4 weeks and 3 months after the treatment.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Geriatrics & Gerontology
Yun-Jo Lo, Viraj Krishna Mishra, Hung-Yao Lo, Navneet Kumar Dubey, Wen-Cheng Lo
Summary: The incidence of insomnia in adults is increasing, negatively impacting quality of life. Insomnia is associated with various disorders and complications, such as cardiovascular diseases, oncologic complications, and asthma. Cognitive behavioral therapy and drug-based therapies are commonly used, but drug-related adverse events limit their long-term application. Traditional Chinese medicine, acupressure, and cryotherapy may provide therapeutic relief.
Article
Geriatrics & Gerontology
Yun-Jo Lo, Viraj Krishna Mishra, Hung-Yao Lo, Navneet Kumar Dubey, Wen-Cheng Lo
Summary: The increasing incidence of insomnia in adults is negatively impacting their quality of life. Insomnia is associated with various disorders and complications, including neurological, cardiovascular, and oncological conditions. Current treatments include cognitive behavioral therapy and drugs, but the adverse effects of drugs limit their long-term use. Traditional Chinese medicine, acupressure, pulsed magnetic field therapy, and cryotherapy offer potential therapeutic relief for insomnia.
Article
Psychology, Clinical
Roz Shafran, Sarah J. Egan, Tracey D. Wade
Summary: This article reviews the controversy surrounding the cognitive behavioural model of clinical perfectionism and cognitive behaviour therapy (CBT) for perfectionism, which has been published for 21 years. Despite 15 randomized controlled trials showing the efficacy of CBT in reducing perfectionism and associated symptoms, there are still strong disagreements in the literature. Future research should focus on independent evaluations, comparing CBT to other treatments, dismantling trials to identify effective components, and studying the causal processes of perfectionism.
BEHAVIOUR RESEARCH AND THERAPY
(2023)
Article
Public, Environmental & Occupational Health
Samantha Conley, Sangchoon Jeon, Laura K. Andrews, Stephen Breazeale, Youri Hwang, Meghan O. ' Connell, Sarah Linsky, Nancy S. Redeker
Summary: This study aimed to analyze the impact of self-care trajectories on adults with heart failure and insomnia, as well as the differences between cognitive behavioral therapy and HF self-care intervention. The results revealed four different self-care trajectories, with no significant influence of the interventions on these trajectories. The low self-care group exhibited the most severe baseline fatigue, anxiety, and perceived stress, as well as the lowest cognitive abilities.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Clinical Neurology
Adrian Meule, Dieter Riemann, Ulrich Voderholzer
Summary: This study examined the changes in sleep quality during inpatient treatment for mental disorders. The results showed that sleep quality was impaired in all diagnostic groups, with trauma-related disorders having the lowest sleep quality and obsessive-compulsive disorder having the highest sleep quality. While sleep quality improved in all groups, the magnitude of improvement varied, with trauma-related disorders showing the smallest improvement and eating disorders showing the largest improvement.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Nausicaa Christodoulou, Lea Bertrand, Laura Palagini, Justine Frija-Masson, Marie-Pia d'Ortho, Michel L. Lejoyeux, Dieter Riennann, Julia Maruani, Pierre A. Geoffroy
Summary: Insomnia symptoms during a fully restrictive lockdown period of Covid-19 are associated with various factors including age, gender, home size, environmental noises, anxiety symptoms, depressive symptoms, regularity of sleep-wake schedules, exposure to screen during the morning, and LED light during the evening. Lifestyle and exposure to natural synchronizers play a crucial role in the development, prevention, and treatment of insomnia, as well as mental health status.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Clinical Neurology
Ellemarije Altena, Chiara Baglioni, Ernesto Sanz-Arigita, Christian Cajochen, Dieter Riemann
Summary: This review examines the impact of heatwaves on night-time temperatures, body temperature, and sleep quality. It discusses the effects of temperature changes on vulnerable populations, such as older adults, children, pregnant women, and individuals with psychiatric conditions. The review suggests various methods, adapted from cognitive behavioural therapy for insomnia, for managing sleep problems during heatwaves. The sparse literature on sleep problems affected by temperature changes highlights the need for further research in this area.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Fee Benz, Dieter Riemann, Katharina Domschke, Kai Spiegelhalder, Anna F. Johann, Nathaniel S. Marshall, Bernd Feige
Summary: The objective of this study was to assess the agreement and linear relationships amongst multiple measures of sleep duration in patients with insomnia disorder and good sleeper controls. The results suggest that subjective and objective measures capture different aspects of sleep, even when addressing the same value. It is important to consider the population being studied and the assessment method when interpreting results.
JOURNAL OF SLEEP RESEARCH
(2023)
Editorial Material
Clinical Neurology
Dieter Riemann
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Florian Holub, Roxana Petri, Julian Schiel, Bernd Feige, Martin K. Rutter, Sandra Tamm, Dieter Riemann, Simon D. Kyle, Kai Spiegelhalder
Summary: This study investigates the associations between insomnia symptoms and resting-state functional connectivity at the whole-brain level using a large sample size. The results suggest that frequent insomnia symptoms are associated with altered functional connectivity between brain networks, which may contribute to dysfunctional affective and cognitive processing and impaired sleep.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Raphael J. J. Dressle, Dieter Riemann, Kai Spiegelhalder, Lukas Frase, Michael L. L. Perlis, Bernd Feige
Summary: According to the hyperarousal model, insomnia is characterized by increased arousal in the cortical, cognitive, and physiological domains. However, the interaction between these arousal domains is poorly understood. This observational case-control study investigated cortical arousal during the night, pre-sleep cognitive arousal, and their relationship in patients with insomnia disorder (ID). The study found that patients with ID exhibited increased cortical and cognitive arousal, particularly in the gamma power of EEG spectral analysis. The findings suggest a potential association between pre-sleep worry and rumination and the elicitation of cortical arousal during the night.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Clinical Neurology
Raphael J. Dressle, Dieter Riemann
Summary: Insomnia disorder is a common mental disorder, and understanding its causes and mechanisms is crucial. Hyperarousal, characterized by increased arousal in physiological, cortical, and cognitive-emotional domains, plays a significant role in insomnia. There is evidence supporting the involvement of neuroendocrine variables and high-frequency brain activity in cortical arousal. Furthermore, the presence of microarousals during sleep and cognitive-emotional hyperarousal, such as insomnia-related thoughts and worries, contribute to the development of insomnia and comorbid mental disorders.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Johanna Ell, Julian E. Schiel, Bernd Feige, Dieter Riemann, Casandra C. Nyhuis, Julio Fernandez-Mendoza, Celine Vetter, Martin K. Rutter, Simon D. Kyle, Kai Spiegelhalder
Summary: This study examined the long-term effects of sleep health and shift work on cognitive performance in middle-aged and older adults using data from the UK Biobank. The results indicated that poor sleep health and shift work significantly predicted lower cognitive performance in this population.
Article
Biology
Janine Traut, Jose Prius Mengual, Elise J. Meijer, Laura E. McKillop, Hannah Alfonsa, Anna Hoerder-Suabedissen, Seo Ho Song, Kristoffer D. Feher, Dieter Riemann, Zoltan Molnar, Colin J. Akerman, Vladyslav V. Vyazovskiy, Lukas B. Krone
Summary: Designer receptors exclusively activated by designer drugs (DREADDs) are chemogenetic tools for remote control of targeted cell populations using chemical actuators that bind to modified receptors. In this study, we demonstrated that the commonly used DREADD actuator, clozapine-N-oxide (CNO), as well as a novel actuator, compound 21 (C21), can modulate sleep in mice not expressing DREADD receptors. Our findings suggest that back-metabolism to clozapine is not the sole mechanism underlying the sleep effects of chemogenetic actuators.
Review
Clinical Neurology
Laura Palagini, Enrico Cipriani, Mario Miniati, Alessandra Bramante, Angelo Gemignani, Pierre A. Geoffroy, Dieter Riemann
Summary: Suicidal risk in mothers is a public health priority, and sleep disturbances are identified as one of the biological factors contributing to increased suicidal risk during the peripartum period. A systematic review revealed that poor sleep quality and insomnia symptoms increase the odds of suicidal risk in pregnant women by more than threefold. Therefore, assessing and addressing sleep disturbances during the peripartum period are crucial in mitigating the adverse effects of peripartum psychopathology and suicidal risk.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Clinical Neurology
Lukas Frase, Christoph Nissen, Kai Spiegelhalder, Bernd Feige
Summary: The importance of polysomnography (PSG) in the diagnosis and treatment of insomnia disorder (ID) is a highly debated topic. This review provides a summary of the current scientific knowledge on PSG indications and findings in ID, and the guidelines for conducting PSG in ID. It also discusses important questions regarding ID subtyping to guide personalized pharmacological and psychotherapeutic treatment approaches.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Clinical Neurology
Carlotta L. Schneider, Elisabeth Hertenstein, Christoph Nissen
Summary: Insomnia is common among psychiatric patients, and cognitive behavioural therapy for insomnia (CBT-I) is the recommended treatment. While CBT-I has been shown to improve insomnia and other health outcomes in outpatient settings, its potential in inpatient psychiatry is unclear. This systematic review identified 10 studies, which reported feasibility and potential efficacy of CBT-I in inpatient settings. However, there is a lack of research on CBT-I in inpatient psychiatry, and adapting CBT-I for severely ill patients in hospital settings could improve mental health care.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Clinical Neurology
Chiara Baglioni, Colin A. Espie, Ellemarije Altena, Dimitri Gavriloff, Susanna Jerneloev, Brigitte Holzinger, Angelika Schlarb, Dieter Riemann
Summary: Although cognitive behavior therapy for insomnia (CBT-I) is the recommended treatment, it is not readily available to those in need. The stepped care model (SCM) offers a solution by providing a pyramid of therapeutics, gradually increasing in intensity, to bridge the treatment gap and distribute resources more effectively. However, high-quality care and training for clinicians, as well as consideration of different interpretations across European countries, are important for successful implementation of the SCM.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Clinical Neurology
Janet M. Y. Cheung, Hannah Scott, Alexandria Muench, Ronald R. Grunstein, Andrew D. Krystal, Dieter Riemann, Michael Perlis
Summary: This article aims to provide guidance for the treatment of insomnia by integrating the analysis of medication safety and efficacy. The study found that histamine antagonists have the best safety and risk-benefit profiles, making them the optimal first-line therapy for insomnia.
JOURNAL OF SLEEP RESEARCH
(2023)
