Alzheimer’s disease: diagnostics, prognostics and the road to prevention

Multiple SNPs Within and Surrounding the Apolipoprotein E Gene Influence Cerebrospinal Fluid Apolipoprotein E Protein Levels

(2017) Lynn M. Bekris et al.   JOURNAL OF ALZHEIMERS DISEASE

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Genome-wide Association Study Implicates a Chromosome 12 Risk Locus for Late-Onset Alzheimer Disease

(2009) Gary W. Beecham et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

(2009)   AMERICAN JOURNAL OF PSYCHIATRY

Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age

(2009) Eloise Kok et al.   ANNALS OF NEUROLOGY

Genetic Testing in Israel: An Overview

(2009) Guy Rosner et al.   Annual Review of Genomics and Human Genetics

Genome-wide association studies in type 2 diabetes

(2009) Mark I. McCarthy et al.   Current Diabetes Reports

Genome-wide association study for type 2 diabetes: clinical applications

(2009) Valeriya Lyssenko et al.   CURRENT OPINION IN LIPIDOLOGY

Pipeline Pharmacogenetics: A Novel Approach to Integrating Pharmacogenetics into Drug Development

(2009) P. Akkari et al.   CURRENT PHARMACEUTICAL DESIGN

The Butyrylcholinesterase K Variant Confers Structurally Derived Risks for Alzheimer Pathology♦

(2009) Erez Podoly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

(2009) Minerva M Carrasquillo et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

The comparative effectiveness challenge

(2009) Bethan Hughes   NATURE REVIEWS DRUG DISCOVERY

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

Validating, augmenting and refining genome-wide association signals

(2009) John P. A. Ioannidis et al.   NATURE REVIEWS GENETICS

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

APOE  4 and bapineuzumab: Infusing pharmacogenomics into Alzheimer disease therapeutics

(2009) D. Kaufer et al.   NEUROLOGY

Relationships between biomarkers in aging and dementia

(2009) W. J. Jagust et al.   NEUROLOGY

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

Common Genetic Variation and Human Traits

(2009) David B. Goldstein   NEW ENGLAND JOURNAL OF MEDICINE

Newborn Screening for Genetic Disorders

(2009) Paul M. Fernhoff   PEDIATRIC CLINICS OF NORTH AMERICA

Hippocampal Atrophy as a Quantitative Trait in a Genome-Wide Association Study Identifying Novel Susceptibility Genes for Alzheimer's Disease

(2009) Steven G. Potkin et al.   PLoS One

Genomic and personalized medicine: foundations and applications

(2009) Geoffrey S. Ginsburg et al.   Translational Research

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

(2008) Lars Bertram et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-Wide Association Studies in Alzheimer Disease

(2008) Stephen C. Waring et al.   ARCHIVES OF NEUROLOGY

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

(2008) Richard Abraham et al.   BMC Medical Genomics

Hypometabolism as a therapeutic target in Alzheimer's disease

(2008) Lauren C Costantini et al.   BMC NEUROSCIENCE

Effect of ApoE Genotype on Response to Donepezil in Patients with Alzheimer’s Disease

(2008) Seong Hye Choi et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

(2008) Lars Bertram et al.   NATURE REVIEWS NEUROSCIENCE

The Medical and Economic Roles of Pipeline Pharmacogenetics: Alzheimer's Disease as a Model of Efficacy and HLA-B*5701 as a Model of Safety

(2008) Allen D Roses   NEUROPSYCHOPHARMACOLOGY

Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons

(2008) J. Brodbeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The amyloid  -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

(2008) C. A. Hansson Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE

Candidate Single-Nucleotide Polymorphisms From a Genomewide Association Study of Alzheimer Disease

(2007) Hao Li et al.   ARCHIVES OF NEUROLOGY