Article
Gastroenterology & Hepatology
Dan Li, Amanda R. Doherty, Menaka Raju, Liyan Liu, Nan Ye Lei, Laura B. Amsden, Jeffrey K. Lee, Theodore R. Levin, Douglas A. Corley, Lisa J. Herrinton
Summary: This community-based, case-control study found a close association between serrated polyps (SPs) and the risk of colorectal cancer (CRC), especially large proximal serrated lesions or those with dysplasia. Close endoscopic surveillance of serrated polyps can help reduce the risk of CRC. Proximal unspecified SPs are also associated with an increased risk of CRC and should be managed as serrated lesions.
Article
Gastroenterology & Hepatology
Szu-Min Peng, Wen-Feng Hsu, Ying-Wei Wang, Li-Ju Lin, Amy Ming-Fang Yen, Li-Sheng Chen, Yi-Chia Lee, Ming-Shiang Wu, Tony Hsiu-Hsi Chen, Han-Mo Chiu
Summary: A study in the Taiwanese Colorectal Cancer Screening Program found that subjects with negative colonoscopy after positive FIT who received subsequent FIT screening had a significantly lower risk of incident CRC, suggesting that scheduling subsequent FIT is important in reducing the risk of missed neoplasms and incident CRC in a national FIT screening program.
Review
Oncology
Maomao Cao, He Li, Dianqin Sun, Siyi He, Yiwen Yu, Jiang Li, Hongda Chen, Jufang Shi, Jiansong Ren, Ni Li, Wanqing Chen
Summary: Substantial progress has been made in cancer screening in China, but challenges such as low participation rates, uneven distribution of medical resources, inadequate funding, and insufficient screening quality remain. To improve the quality of cancer screening, efforts should focus on strengthening advertising, providing training, optimizing the definition of high-risk populations, integrating new technologies, and implementing appropriate management measures.
Article
Gastroenterology & Hepatology
Paulina Wieszczy, Elisabeth Waldmann, Magnus Loberg, Jaroslaw Regula, Maciej Rupinski, Marek Bugajski, Kathryn Gray, Mette Kalager, Monika Ferlitsch, Michal F. Kaminski, Michael Bretthauer
Summary: The study showed that the performance of colonoscopists may affect colorectal cancer risk after adenoma removal. Individuals with low-risk or high-risk adenomas examined by low-performing colonoscopists had significantly higher colorectal cancer incidence compared to those examined by high-performing colonoscopists.
Article
Gastroenterology & Hepatology
Yazmin San Miguel, Joshua Demb, Maria Elena Martinez, Samir Gupta, Folasade P. May
Summary: The study found that delayed colonoscopy completion after an abnormal stool-based colorectal cancer screening test is associated with higher risk of CRC incidence, death, and late-stage CRC. Therefore, interventions to improve CRC outcomes should emphasize diagnostic follow-up within 1 year of abnormal screening results.
Review
Gastroenterology & Hepatology
Hermann Brenner, Thomas Heisser, Rafael Cardoso, Michael Hoffmeister
Summary: In the era of widespread uptake of screening colonoscopy, CRC incidence rates decreased by up to 50% in older age groups in the USA, despite adverse trends in CRC risk factors and increasing CRC incidence at younger ages. However, first results from a randomized trial suggest rather modest effects of screening colonoscopy. The apparent discrepancy between real-world and trial evidence can be explained by factors such as limited screening adherence, widespread uptake of colonoscopy outside the screening offers, and the inclusion of prevalent, non-preventable CRC cases in reported numbers of incident cases. Alternative interpretations of screening endoscopy trial results accounting for prevalence bias are in line with trends in countries offering CRC screening, and should encourage more widespread implementation and uptake of effective CRC screening.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Shivan J. Mehta, Catherine Reitz, Tess Niewood, Kevin G. Volpp, David A. Asch
Summary: The study showed that financial incentives in colorectal cancer risk assessment can increase completion rates among participants, but did not significantly increase the completion rate of screening colonoscopy.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Arthur I. Kooyker, Esther Toes-Zoutendijk, Annemieke W. J. Opstal-van Winden, Maaike Buskermolen, Hanneke J. van Vuuren, Ernst J. Kuipers, Folkert J. van Kemenade, Chris Ramakers, Evelien Dekker, Iris D. Nagtegaal, Harry J. de Koning, Manon C. W. Spaander, Iris Lansdorp-Vogelaar, Monique E. van Leerdam
Summary: The colonoscopy-related mortality within the Dutch FIT-based CRC screening program was estimated to range from 0.23 to 0.91 per 10,000 FIT-positive participants undergoing colonoscopy, with 50% of likely colonoscopy-related causes of death being cardiovascular events.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Swati G. Patel, Folasade P. May, Joseph C. Anderson, Carol A. Burke, Jason A. Dominitz, Seth A. Gross, Brian C. Jacobson, Aasma Shaukat, Douglas J. Robertson
Summary: This updated recommendation suggests starting colorectal cancer screening at age 45 based on increasing disease burden and modeling studies showing benefits outweigh potential harms and costs, while recommending individualized decisions for screening in individuals aged 76 to 85.
Article
Gastroenterology & Hepatology
M. Maida, B. Annibale, A. Benedetti, P. Burra, L. Frulloni, G. Ianiro, F. Luzza, A. Repici, E. Savarino, E. Sinagra, M. Vecchi, L. Ricciardiello
Summary: The quality of endoscopic screening for colorectal cancer (CRC) in Italy is generally high, but there are also significant deficiencies and discrepancies in procedural attitudes between different centers. Urgent action is needed to address these shortcomings, improve the behavior of all screening centers, and enhance outcomes.
DIGESTIVE AND LIVER DISEASE
(2022)
Article
Gastroenterology & Hepatology
Ansgar Deibel, Lu Deng, Chih-Yuan Cheng, Michael Schlander, Tao Ran, Brian Lang, Niklas Krupka, Niko Beerenwinkel, Gerhard Rogler, Reiner Wiest, Amnon Sonnenberg, Jan Poleszczuk, Benjamin Misselwitz
Summary: The study aimed to identify the characteristics of highly efficient theoretical screening tests and evaluate the effectiveness and cost-effectiveness of available screening tests for colorectal cancer. The findings indicated that highly efficient theoretical screening tests have high sensitivity and patient adherence, while all available screening tests were effective and cost-efficient at expected adherence rates.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Public, Environmental & Occupational Health
Gretel Jianlin Wong, Jerrald Lau, Emily Chew, Wen-Min Chow, Julia Choo, Ker-Kan Tan
Summary: This study aimed to understand CRC patients' views and receptiveness of having their surveillance consultations conducted in a community setting. Results showed that most participants still preferred to be managed by their primary surgeon and were hesitant towards having their follow-up surveillance consultations in community and primary care settings.
Article
Gastroenterology & Hepatology
Jasmin Zessner-Spitzenberg, Lena Jiricka, Elisabeth Waldmann, Lisa -Maria Rockenbauer, Jeremy Cook, Anna Hinterberger, Barbara Majcher, Aleksandra Szymanska, Arno Asaturi, Michael Trauner, Monika Ferlitsch
Summary: A retrospective study with 316,001 individuals revealed that polyps sized 10-20mm and high-grade dysplasia are significantly associated with post-colonoscopy colorectal cancer (PCCRC) mortality. Patients with polyps <10mm and without high-grade dysplasia have significantly lower PCCRC mortality compared to the general population, while those with polyps >10mm or with high-grade dysplasia do not have this advantage.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Multidisciplinary Sciences
Muhammad Imran, Mukhtiar Baig, Razan Obaidallah Alshuaibi, Thikra Abdullah Almohammadi, Samah Abdulsalam Albeladi, Faysal Turki Matuq Zaafarani
Summary: This study investigated the knowledge, awareness, and barriers to colorectal cancer screening in the general population of Saudi Arabia. The results showed insufficient knowledge, poor awareness, and various barriers among the participants. There is a need to bridge the knowledge gap and provide comprehensive information, utilizing social media for promotion.
Review
Oncology
Marta Maes-Carballo, Manuel Garcia-Garcia, Manuel Martin-Diaz, Carlos Roberto Estrada-Lopez, Andres Iglesias-Alvarez, Carmen Milagros Filigrana-Valle, Khalid Saeed Khan, Aurora Bueno-Cavanillas
Summary: This study evaluated the quality and reporting of colorectal cancer screening clinical practice guidelines and consensus statements. The findings showed low quality and reporting in these guidelines, highlighting the need for revision and improvement. Guidelines that utilized systematic reviews demonstrated better quality and reporting.
BRITISH JOURNAL OF CANCER
(2023)
