Saturation mutagenesis of selected residues of the α-peptide of the lantibiotic lacticin 3147 yields a derivative with enhanced antimicrobial activity

Bioengineered Nisin A Derivatives with Enhanced Activity against Both Gram Positive and Gram Negative Pathogens

(2012) Des Field et al.   PLoS One

Bioengineered nisin derivatives with enhanced activity in complex matrices

(2012) Susan Rouse et al.   Microbial Biotechnology

Homologues and Bioengineered Derivatives of LtnJ Vary in Ability to Form D-Alanine in the Lantibiotic Lacticin 3147

(2011) S. Suda et al.   JOURNAL OF BACTERIOLOGY

Haloduracin α Binds the Peptidoglycan Precursor Lipid II with 2:1 Stoichiometry

(2011) Trent J. Oman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Production of a Class II Two-Component Lantibiotic of Streptococcus pneumoniae Using the Class I Nisin Synthetic Machinery and Leader Sequence

(2010) J. A. Majchrzykiewicz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparison of the activities of the lantibiotics nisin and lacticin 3147 against clinically significant mycobacteria

(2010) James Carroll et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The dawning of a ‘Golden era’ in lantibiotic bioengineering

(2010) Des Field et al.   MOLECULAR MICROBIOLOGY

Studies with bioengineered Nisin peptides highlight the broad-spectrum potency of Nisin V

(2010) Des Field et al.   Microbial Biotechnology

Identification of a Novel Two-Peptide Lantibiotic, Lichenicidin, following Rational Genome Mining for LanM Proteins

(2009) M. Begley et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Dissecting Structural and Functional Diversity of the Lantibiotic Mersacidin

(2009) Antony N. Appleyard et al.   CHEMISTRY & BIOLOGY

Lantibiotics: Mode of Action, Biosynthesis and Bioengineering

(2009) G. Bierbaum et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

A comparison of the activities of lacticin 3147 and nisin against drug-resistant Staphylococcus aureus and Enterococcus species

(2009) C. Piper et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of essential and variable residues of nukacin ISK-1 by NNK scanning

(2009) Mohammad R. Islam et al.   MOLECULAR MICROBIOLOGY

Organization of the genes encoding the biosynthesis of actagardine and engineering of a variant generation system

(2009) Steven Boakes et al.   MOLECULAR MICROBIOLOGY

Production of the Novel Two-Peptide Lantibiotic Lichenicidin by Bacillus licheniformis DSM 13

(2009) Jasmin Dischinger et al.   PLoS One

Manipulation of charged residues within the two-peptide lantibiotic lacticin 3147

(2009) Lucy H. Deegan et al.   Microbial Biotechnology

Structure-Activity Relationship Studies of the Two-Component Lantibiotic Haloduracin

(2008) Lisa E. Cooper et al.   CHEMISTRY & BIOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

The generation of nisin variants with enhanced activity against specific Gram-positive pathogens

(2008) Des Field et al.   MOLECULAR MICROBIOLOGY