Tregs in infection and vaccinology: heroes or traitors?

T Regulatory Cells Contribute to the Attenuated Primary CD8+ and CD4+ T Cell Responses to Herpes Simplex Virus Type 2 in Neonatal Mice

(2014) M. A. Fernandez et al.   JOURNAL OF IMMUNOLOGY

IL-10 and Natural Regulatory T Cells: Two Independent Anti-Inflammatory Mechanisms in Herpes Simplex Virus-Induced Ocular Immunopathology

(2014) Pranita P. Sarangi et al.   JOURNAL OF IMMUNOLOGY

The adjuvant effect of TLR agonists on CD4+ effector T cells is under the indirect control of regulatory T cells

(2011) Aurélie Olivier et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Treatment with the TLR7 agonist R848 induces regulatory T-cell-mediated suppression of established asthma symptoms

(2011) Linh Pham Van et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice

(2011) Rafael Prados-Rosales et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulatory T Cells Selectively Control CD8+ T Cell Effector Pool Size via IL-2 Restriction

(2011) W. Kastenmuller et al.   JOURNAL OF IMMUNOLOGY

Initiation and regulation of T-cell responses in tuberculosis

(2011) K B Urdahl et al.   Mucosal Immunology

Dominant TNF-α+ Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease

(2011) Alexandre Harari et al.   NATURE MEDICINE

Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points

(2011) K. K. Dietze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

(2011) A. McNally et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

Immunomodulatory effects of cyclophosphamide and implementations for vaccine design

(2011) Antonella Sistigu et al.   Seminars in Immunopathology

Selective Depletion of Foxp3+ Regulatory T Cells Improves Effective Therapeutic Vaccination against Established Melanoma

(2010) K. Klages et al.   CANCER RESEARCH

Conditional Regulatory T-Cell Depletion Releases Adaptive Immunity Preventing Carcinogenesis and Suppressing Established Tumor Growth

(2010) M. W. L. Teng et al.   CANCER RESEARCH

Two Distinct Mechanisms of Augmented Antitumor Activity by Modulation of Immunostimulatory/Inhibitory Signals

(2010) J. Mitsui et al.   CLINICAL CANCER RESEARCH

Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function

(2010) Yan Xiao et al.   CURRENT OPINION IN IMMUNOLOGY

Regulatory T cells in human geohelminth infection suppress immune responses to BCG andPlasmodium falciparum

(2010) Linda J. Wammes et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Selective depletion of Foxp3+ Treg during sensitization phase aggravates experimental allergic airway inflammation

(2010) Abdul Mannan Baru et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tolerance Rather Than Immunity Protects From Helicobacter pylori–Induced Gastric Preneoplasia

(2010) Isabelle C. Arnold et al.   GASTROENTEROLOGY

Extracellular NAD+shapes the Foxp3+regulatory T cell compartment through the ART2–P2X7 pathway

(2010) Sandra Hubert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis

(2010) Shahin Shafiani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

(2010) John R. Grainger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice

(2010) N. Casares et al.   JOURNAL OF IMMUNOLOGY

Foxp3+ CD4 Regulatory T Cells Limit Pulmonary Immunopathology by Modulating the CD8 T Cell Response during Respiratory Syncytial Virus Infection

(2010) R. B. Fulton et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells Support Homeostatic Expansion of Foxp3 + Regulatory T Cells in Foxp3.LuciDTR Mice

(2010) Janine Suffner et al.   JOURNAL OF IMMUNOLOGY

Combining T-cell Vaccination and Application of Agonistic Anti-GITR mAb (DTA-1) Induces Complete Eradication of HPV Oncogene Expressing Tumors in Mice

(2010) Corinna Hoffmann et al.   JOURNAL OF IMMUNOTHERAPY

Effect of CD4+CD25+ regulatory T cells on the immune evasion of Schistosoma japonicum

(2010) Chun-lian Tang et al.   PARASITOLOGY RESEARCH

Plasmodium vivax: Induction of CD4+CD25+FoxP3+ Regulatory T Cells during Infection Are Directly Associated with Level of Circulating Parasites

(2010) Lilian Lacerda Bueno et al.   PLoS One

CD4+ Natural Regulatory T Cells Prevent Experimental Cerebral Malaria via CTLA-4 When Expanded In Vivo

(2010) Ashraful Haque et al.   PLoS Pathogens

Clinical Use of Anti-CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells

(2009) Andrew J. Rech et al.   Annals of the New York Academy of Sciences

Regulatory T Cells in the Control of Host-Microorganism Interactions

(2009) Yasmine Belkaid et al.   Annual Review of Immunology

Establishment of nematode infection despite increased Th2 responses and immunopathology after selective depletion of Foxp3+cells

(2009) Sebastian Rausch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Helicobacter pylori Immune Escape Is Mediated by Dendritic Cell–Induced Treg Skewing and Th17 Suppression in Mice

(2009) John Y. Kao et al.   GASTROENTEROLOGY

Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection

(2009) Guillaume Oldenhove et al.   IMMUNITY

Limited Role of CD4+Foxp3+ Regulatory T Cells in the Control of Experimental Cerebral Malaria

(2009) C. Steeg et al.   JOURNAL OF IMMUNOLOGY

Engagement of TLR2 Does not Reverse the Suppressor Function of Mouse Regulatory T Cells, but Promotes Their Survival

(2009) Q. Chen et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Suppress Antiviral Immune Responses and Increase Viral Loads during Acute Infection with a Lymphotropic Retrovirus

(2009) Gennadiy Zelinskyy et al.   PLoS Pathogens

Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines

(2008) M. A. Morse et al.   BLOOD

Paradoxical Roles of Foxp3+ T Cells during Infection: From Regulators to Regulators

(2008) Yasmine Belkaid   Cell Host & Microbe

Circumvention of regulatory CD4+ T cell activity during cross-priming strongly enhances T cell-mediated immunity

(2008) Antje Heit et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Helicobacter pylori Gastritis in Children Is Associated With a Regulatory T-Cell Response

(2008) Paul R. Harris et al.   GASTROENTEROLOGY

Role of Endogenous and Induced Regulatory T Cells During Infections

(2008) Elizabeth Wohlfert et al.   JOURNAL OF CLINICAL IMMUNOLOGY

HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase–dependent mechanism

(2008) Olivier Manches et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria

(2008) M. G. Torcia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells

(2008) J. M. Lund et al.   SCIENCE

Poor immunogenicity of BCG in helminth infected population is associated with increased in vitro TGF-β production

(2008) Daniel Elias et al.   VACCINE

Co-Immunization of Mice with a Retroviral DNA Vaccine and GITRL-Encoding Plasmid Augments Vaccine-Induced Protection Against Retrovirus Infection

(2008) Ulf Dittmer et al.   VIRAL IMMUNOLOGY

IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection

(2008) Kevin N. Couper et al.   PLoS Pathogens