WAVE2 Protein Complex Coupled to Membrane and Microtubules

WAVE2, N-WASP, and mena facilitate cell invasion via phosphatidylinositol 3-kinase-dependent local accumulation of actin filaments

(2011) Kazuhide Takahashi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nonmuscle myosin IIA is required for lamellipodia formation through binding to WAVE2 and phosphatidylinositol 3,4,5-triphosphate

(2010) Shigeru Morimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

WAVE2 targeting to phosphatidylinositol 3,4,5-triphosphate mediated by insulin receptor substrate p53 through a complex with WAVE2

(2010) Kazuhide Takahashi et al.   CELLULAR SIGNALLING

Localization of Myosin 1b to Actin Protrusions Requires Phosphoinositide Binding

(2010) Shigeru Komaba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PtdIns(3,4,5)P3 is a regulator of myosin-X localization and filopodia formation

(2010) L. Plantard et al.   JOURNAL OF CELL SCIENCE

Electron tomography reveals unbranched networks of actin filaments in lamellipodia

(2010) Edit Urban et al.   NATURE CELL BIOLOGY

βPIX and GIT1 regulate HGF-induced lamellipodia formation and WAVE2 transport

(2009) Shigeru Morimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Membrane transport of WAVE2 and lamellipodia formation require Pak1 that mediates phosphorylation and recruitment of stathmin/Op18 to Pak1–WAVE2–kinesin complex

(2009) Kazuhide Takahashi et al.   CELLULAR SIGNALLING

Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3,4,5-triphosphate

(2009) Kazuhide Takahashi et al.   CELLULAR SIGNALLING

Mammalian end binding proteins control persistent microtubule growth

(2009) Yulia Komarova et al.   JOURNAL OF CELL BIOLOGY

Regulation of lamellipodia formation and cell invasion by CLIP-170 in invasive human breast cancer cells

(2008) Katsuo Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

WAVE2- and microtubule-dependent formation of long protrusions and invasion of cancer cells cultured on three-dimensional extracellular matrices

(2008) Keiji Kikuchi et al.   CANCER SCIENCE

Requirement of kinesin-mediated membrane transport of WAVE2 along microtubules for lamellipodia formation promoted by hepatocyte growth factor

(2008) Kazuhide Takahashi et al.   EXPERIMENTAL CELL RESEARCH

CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites

(2008) Peter Bieling et al.   JOURNAL OF CELL BIOLOGY

Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2

(2008) W. Abou-Kheir et al.   JOURNAL OF CELL SCIENCE

Comprehensive Identification of PIP3-Regulated PH Domains from C. elegans to H. sapiens by Model Prediction and Live Imaging

(2008) Wei Sun Park et al.   MOLECULAR CELL

Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front

(2008) Stefan A. Koestler et al.   NATURE CELL BIOLOGY

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

(2008) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Correlated waves of actin filaments and PIP3inDictyosteliumcells

(2008) Yukako Asano et al.   CELL MOTILITY AND THE CYTOSKELETON