Flotillins in Receptor Tyrosine Kinase Signaling and Cancer

Phosphatidylinositol 3-Kinase dependent upregulation of the epidermal growth factor receptor upon Flotillin-1 depletion in breast cancer cells

(2013) Nina Kurrle et al.   BMC CANCER

Increased activity of mitogen activated protein kinase pathway in flotillin-2 knockout mouse model

(2013) Antje Banning et al.   CELLULAR SIGNALLING

Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount

(2013) Melanie Meister et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Flotillin-2 is associated with breast cancer progression and poor survival outcomes

(2013) Xi Wang et al.   Journal of Translational Medicine

Microrna-124 targets flotillin-1 to regulate proliferation and migration in breast cancer

(2013) Laisheng Li et al.   Molecular Cancer

Flotillin2 Expression Correlates with HER2 Levels and Poor Prognosis in Gastric Cancer

(2013) Zhi Zhu et al.   PLoS One

High Expression of FLOT1 Is Associated with Progression and Poor Prognosis in Hepatocellular Carcinoma

(2013) Shi-Hong Zhang et al.   PLoS One

Ezrin/Radixin/Moesin Proteins and Flotillins Cooperate to Promote Uropod Formation in T Cells

(2013) Sibylla Martinelli et al.   Frontiers in Immunology

Flotillin-1 Promotes Tumor Necrosis Factor-α Receptor Signaling and Activation of NF-κB in Esophageal Squamous Cell Carcinoma Cells

(2012) Libing Song et al.   GASTROENTEROLOGY

Flotillin-1/Reggie-2 Protein Plays Dual Role in Activation of Receptor-tyrosine Kinase/Mitogen-activated Protein Kinase Signaling

(2012) Monia Amaddii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reggies/flotillins regulate E-cadherin–mediated cell contact formation by affecting EGFR trafficking

(2012) Gonzalo P. Solis et al.   MOLECULAR BIOLOGY OF THE CELL

Flotillins as regulators of ErbB2 levels in breast cancer

(2012) S Pust et al.   ONCOGENE

Flotillin-2 deficiency leads to reduced lung metastases in a mouse breast cancer model

(2012) T Berger et al.   ONCOGENE

Molecular Networks in FGF Signaling: Flotillin-1 and Cbl-Associated Protein Compete for the Binding to Fibroblast Growth Factor Receptor Substrate 2

(2012) Ana Tomasovic et al.   PLoS One

Transcriptional Regulation of Flotillins by the Extracellularly Regulated Kinases and Retinoid X Receptor Complexes

(2012) Antje Banning et al.   PLoS One

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes

(2011) Sarah Affentranger et al.   BMC CELL BIOLOGY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Knockdown of FLOT1 Impairs Cell Proliferation and Tumorigenicity in Breast Cancer through Upregulation of FOXO3a

(2011) C. Lin et al.   CLINICAL CANCER RESEARCH

Functional Aspects of Membrane Association of Reggie/Flotillin Proteins

(2011) Antje Banning et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Exosome Secretion Ameliorates Lysosomal Storage of Cholesterol in Niemann-Pick Type C Disease

(2010) Katrin Strauss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment

(2010) Alexander Ludwig et al.   JOURNAL OF CELL BIOLOGY

Revitalizing membrane rafts: new tools and insights

(2010) Kai Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hetero-oligomerization of reggie-1/flotillin-2 and reggie-2/flotillin-1 is required for their endocytosis

(2009) Tanja Babuke et al.   CELLULAR SIGNALLING

Endocytosis of flotillin-1 and flotillin-2 is regulated by Fyn kinase

(2009) K. Riento et al.   JOURNAL OF CELL SCIENCE

Flotillins Interact with PSGL-1 in Neutrophils and, upon Stimulation, Rapidly Organize into Membrane Domains Subsequently Accumulating in the Uropod

(2009) Jérémie Rossy et al.   PLoS One

Flotillins Are Involved in the Polarization of Primitive and Mature Hematopoietic Cells

(2009) Lawrence Rajendran et al.   PLoS One

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins

(2008) Noriko Gotoh   CANCER SCIENCE

The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells

(2008) Joe W. Ramos   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY