Comprehensive Analysis of Germline Variants in Mexican Patients with Hereditary Breast and Ovarian Cancer Susceptibility

Variants of cancer susceptibility genes in Korean BRCA1/2 mutation-negative patients with high risk for hereditary breast cancer

(2018) Ji Soo Park et al.   BMC CANCER

A multi-gene panel study in hereditary breast and ovarian cancer in Colombia

(2017) A. M. Cock-Rada et al.   Familial Cancer

Genomic analysis of inherited breast cancer among Palestinian women: Genetic heterogeneity and a founder mutation in TP53

(2017) Suhair Lolas Hamameh et al.   INTERNATIONAL JOURNAL OF CANCER

Genome-wide two-locus interaction analysis identifies multiple epistatic SNP pairs that confer risk of prostate cancer: A cross-population study

(2017) Jiawei Shen et al.   INTERNATIONAL JOURNAL OF CANCER

Germline mutations predisposing to diffuse large B-cell lymphoma

(2017) O C Leeksma et al.   Blood Cancer Journal

Multiple-gene panel analysis in a case series of 255 women with hereditary breast and ovarian cancer

(2017) Gianluca Tedaldi et al.   Oncotarget

Aryl Hydrocarbon Receptor–Interacting Protein (AIP) N-Terminus Gene Mutations Identified in Pituitary Adenoma Patients Alter Protein Stability and Function

(2017) Robert Formosa et al.   Hormones & Cancer

Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer

(2017) Fergus J. Couch et al.   JAMA Oncology

Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer

(2016) Kara N. Maxwell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Modifiers of breast and ovarian cancer risks forBRCA1andBRCA2mutation carriers

(2016) Roger L Milne et al.   ENDOCRINE-RELATED CANCER

Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics

(2016) Sarah S. Kalia et al.   GENETICS IN MEDICINE

Prioritizing Variants in Complete Hereditary Breast and Ovarian Cancer Genes in Patients Lacking Known BRCA Mutations

(2016) Natasha G. Caminsky et al.   HUMAN MUTATION

Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2

(2016) Cornelia Kraus et al.   INTERNATIONAL JOURNAL OF CANCER

Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India

(2016) Ashraf U Mannan et al.   JOURNAL OF HUMAN GENETICS

Prevalence ofBRCA1/2germline mutations in 21 401 families with breast and ovarian cancer

(2016) Karin Kast et al.   JOURNAL OF MEDICAL GENETICS

Detection of Germline Mutation in Hereditary Breast and/or Ovarian Cancers by Next-Generation Sequencing on a Four-Gene Panel

(2016) Ava Kwong et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The Fanconi anaemia pathway: new players and new functions

(2016) Raphael Ceccaldi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

(2016) S. P. Kar et al.   Cancer Discovery

Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer

(2016) Po-Han Lin et al.   Oncotarget

HBOC multi-gene panel testing: comparison of two sequencing centers

(2015) Christopher Schroeder et al.   BREAST CANCER RESEARCH AND TREATMENT

The spectrum of BRCA1 and BRCA2 alleles in Latin America and the Caribbean: a clinical perspective

(2015) Julie Dutil et al.   BREAST CANCER RESEARCH AND TREATMENT

Exploring the landscape of pathogenic genetic variation in the ExAC population database: insights of relevance to variant classification

(2015) Wei Song et al.   GENETICS IN MEDICINE

Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing

(2015) Lisa R. Susswein et al.   GENETICS IN MEDICINE

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families

(2015) Jun Li et al.   JOURNAL OF MEDICAL GENETICS

A Systematic Comparison of Traditional and Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Genes in More Than 1000 Patients

(2015) Stephen E. Lincoln et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

(2015) Kyriaki Michailidou et al.   NATURE GENETICS

Patterns and functional implications of rare germline variants across 12 cancer types

(2015) Charles Lu et al.   Nature Communications

Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment

(2015) Andrea Desmond et al.   JAMA Oncology

Multigene panel analysis identified germline mutations of DNA repair genes in breast and ovarian cancer

(2015) Yosuke Hirotsu et al.   Molecular Genetics & Genomic Medicine

Frequency of mutations in individuals with breast cancer referred forBRCA1andBRCA2testing using next-generation sequencing with a 25-gene panel

(2014) Nadine Tung et al.   CANCER

Recurrent BRCA1 and BRCA2 Mutations in Mexican Women with Breast Cancer

(2014) G. Torres-Mejia et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Modifiers of Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A Systematic Review and Meta-Analysis

(2014) Tara M. Friebel et al.   JNCI-Journal of the National Cancer Institute

C-terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin

(2013) Sicheng Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Large Numbers of Genetic Variants Considered to be Pathogenic are Common in Asymptomatic Individuals

(2013) Christopher A. Cassa et al.   HUMAN MUTATION

Epistatic interaction of Arg72Pro TP53 and −710 C/T VEGFR1 polymorphisms in breast cancer: predisposition and survival

(2013) Patricia Rodrigues et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Assessing SNP-SNP Interactions among DNA Repair, Modification and Metabolism Related Pathway Genes in Breast Cancer Susceptibility

(2013) Yadav Sapkota et al.   PLoS One

Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk

(2013) Mia M. Gaudet et al.   PLoS Genetics

Three novel functional polymorphisms in the promoter of FGFR2 gene and breast cancer risk: a HuGE review and meta-analysis

(2012) Liping Zhou et al.   BREAST CANCER RESEARCH AND TREATMENT

Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

(2012) N. Mavaddat et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

(2012) D. G. MacArthur et al.   SCIENCE

Large-scale Exploration of Gene-Gene Interactions in Prostate Cancer Using a Multistage Genome-wide Association Study

(2011) J. Ciampa et al.   CANCER RESEARCH

Crosstalk Between the FGFR2 and TP53 Genes in Breast Cancer: Data from an Association Study and Epistatic Interaction Analysis

(2011) Nadezhda V. Cherdyntseva et al.   DNA AND CELL BIOLOGY

Germline Mutations in MSR1, ASCC1, and CTHRC1 in Patients With Barrett Esophagus and Esophageal Adenocarcinoma

(2011) Mohammed Orloff et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Phosphodiesterase 11A (PDE11A) Genetic Variants May Increase Susceptibility to Prostatic Cancer

(2010) Fabio Rueda Faucz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Epistatic interactions between loci of one-carbon metabolism modulate susceptibility to breast cancer

(2010) Shaik Mohammad Naushad et al.   MOLECULAR BIOLOGY REPORTS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

First Breast Cancer Mammography Screening Program in Mexico: Initial Results 2005-2006

(2009) Sergio Rodríguez-Cuevas et al.   Breast Journal

Functional Phosphodiesterase 11A Mutations May Modify the Risk of Familial and Bilateral Testicular Germ Cell Tumors

(2009) Anelia Horvath et al.   CANCER RESEARCH

Mutational analysis of FANCL , FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer predisposition

(2009) María J. García et al.   CARCINOGENESIS

Genomic rearrangements in BRCA1 and BRCA2: a literature review

(2009) Ingrid Petroni Ewald et al.   GENETICS AND MOLECULAR BIOLOGY