Auranofin, an Anti-Rheumatic Gold Compound, Modulates Apoptosis by Elevating the Intracellular Calcium Concentration ([Ca2+]i) in MCF-7 Breast Cancer Cells

Cisplatin (CDDP) triggers cell death of MCF-7 cells following disruption of intracellular calcium ([Ca2+]i) homeostasis

(2014) Nawaf Al-Taweel et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Cytosolic Ca2+ shifts as early markers of cytotoxicity

(2013) Philippe Wyrsch et al.   Cell Communication and Signaling

Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase

(2013) Chaoran Liu et al.   PLoS One

Stimulation of human TRPA1 channels by clinical concentrations of the antirheumatic drug auranofin

(2012) Noriyuki Hatano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Modulation of doxorubicin cytotoxicity by resveratrol in a human breast cancer cell line

(2012) Abdel-Moneim M Osman et al.   Cancer Cell International

A new target for gold(I) compounds: Glutathione-S-transferase inhibition by auranofin

(2012) Anastasia De Luca et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Proteomic analysis of ovarian cancer cell responses to cytotoxic gold compounds

(2012) Francesca Guidi et al.   Metallomics

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

(2011) Ana-Maria Florea et al.   Cancers

Novel Metals and Metal Complexes as Platforms for Cancer Therapy

(2010) Michael Frezza et al.   CURRENT PHARMACEUTICAL DESIGN

Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study

(2010) Francesca Magherini et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity

(2010) Aya Nakaya et al.   LEUKEMIA RESEARCH

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

(2009) Valentina Gandin et al.   BIOCHEMICAL PHARMACOLOGY

Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study

(2009) Angela Casini et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Anti-cancer drugs interfere with intracellular calcium signaling

(2009) Ana-Maria Florea et al.   NEUROTOXICOLOGY

Co-application of arsenic trioxide (As2O3) and cisplatin (CDDP) on human SY-5Y neuroblastoma cells has differential effects on the intracellular calcium concentration ([Ca2+]i) and cytotoxicity

(2008) Dennis Alexander Günes et al.   NEUROTOXICOLOGY

IP3 receptor antagonist, 2-APB, attenuates cisplatin induced Ca2+-influx in HeLa-S3 cells and prevents activation of calpain and induction of apoptosis

(2007) F Splettstoesser et al.   BRITISH JOURNAL OF PHARMACOLOGY