HEXIM1, a New Player in the p53 Pathway

Identification of HEXIM1 as a Positive Regulator of p53

(2012) Qiao Jing Lew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitination of HEXIM1 by HDM2

(2011) Joanne Lau et al.   CELL CYCLE

NPMc+ AML cell line shows differential protein expression and lower sensitivity to DNA-damaging and p53-inducing anticancer compounds

(2011) Qiao Jing Lew et al.   CELL CYCLE

Camptothecin releases P-TEFb from the inactive 7SK snRNP complex

(2010) Stefano Amente et al.   CELL CYCLE

CLP-1 associates with MyoD and HDAC to restore skeletal muscle cell regeneration

(2010) J. Galatioto et al.   JOURNAL OF CELL SCIENCE

The C terminus of p53 binds the N-terminal domain of MDM2

(2010) Masha V Poyurovsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Polo-Like Kinase 2-Dependent Phosphorylation of NPM/B23 on Serine 4 Triggers Centriole Duplication

(2010) Annekatrin Krause et al.   PLoS One

Ascochlorin activates p53 in a manner distinct from DNA damaging agents

(2009) Ji-Hak Jeong et al.   INTERNATIONAL JOURNAL OF CANCER

Specificity of Hexim1 and Hexim2 Complex Formation with Cyclin T1/T2, Importin α and 7SK snRNA

(2009) Nadine Czudnochowski et al.   JOURNAL OF MOLECULAR BIOLOGY

A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP

(2009) Y. Xue et al.   NUCLEIC ACIDS RESEARCH

Nucleophosmin Interacts with HEXIM1 and Regulates RNA Polymerase II Transcription

(2008) Meera Gurumurthy et al.   JOURNAL OF MOLECULAR BIOLOGY

LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated

(2008) B. J. Krueger et al.   NUCLEIC ACIDS RESEARCH