Epigenetics of Estrogen Receptor Signaling: Role in Hormonal Cancer Progression and Therapy

Functional Activation of the Estrogen Receptor-  and Aromatase by the HDAC Inhibitor Entinostat Sensitizes ER-Negative Tumors to Letrozole

(2011) G. J. Sabnis et al.   CANCER RESEARCH

Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer

(2010) E. A. Reijm et al.   BREAST CANCER RESEARCH AND TREATMENT

Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo

(2010) Sha Hu et al.   CANCER BIOLOGY & THERAPY

Regulation of Tumor Angiogenesis by EZH2

(2010) Chunhua Lu et al.   CANCER CELL

Potential Role of Pargyline in Overcoming Adaptive Resistance in Breast Cancer Cells.

(2010) V. Cortez et al.   CANCER RESEARCH

Extranuclear Functions of ER Impact Invasive Migration and Metastasis by Breast Cancer Cells

(2010) D. Chakravarty et al.   CANCER RESEARCH

The Histone Demethylase JMJD2B Is Regulated by Estrogen Receptor   and Hypoxia, and Is a Key Mediator of Estrogen Induced Growth

(2010) J. Yang et al.   CANCER RESEARCH

Protein arginine deiminase 4: a target for an epigenetic cancer therapy

(2010) Jessica L. Slack et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-α target gene activation by regulating lysine demethylase 1 specificity

(2010) Sujit S Nair et al.   EMBO REPORTS

Histone arginine methylation

(2010) Alessandra Di Lorenzo et al.   FEBS LETTERS

Epigenetic Regulation in Estrogen Receptor Positive Breast Cancer—Role in Treatment Response

(2010) Thushangi N. Pathiraja et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Genomic Collaboration of Estrogen Receptor   and Extracellular Signal-Regulated Kinase 2 in Regulating Gene and Proliferation Programs

(2010) Z. Madak-Erdogan et al.   MOLECULAR AND CELLULAR BIOLOGY

Enhancer of Zeste Homolog 2 Promotes the Proliferation and Invasion of Epithelial Ovarian Cancer Cells

(2010) H. Li et al.   MOLECULAR CANCER RESEARCH

TDRD3 Is an Effector Molecule for Arginine-Methylated Histone Marks

(2010) Yanzhong Yang et al.   MOLECULAR CELL

Minireview: Role of Kinases and Chromatin Remodeling in Progesterone Signaling to Chromatin

(2010) Guillermo P. Vicent et al.   MOLECULAR ENDOCRINOLOGY

Xenoestrogen-Induced Regulation of EZH2 and Histone Methylation via Estrogen Receptor Signaling to PI3K/AKT

(2010) Tiffany G. Bredfeldt et al.   MOLECULAR ENDOCRINOLOGY

Epigenetic modifications as therapeutic targets

(2010) Theresa K Kelly et al.   NATURE BIOTECHNOLOGY

The HDAC inhibitor LBH589 (panobinostat) is an inhibitory modulator of aromatase gene expression

(2010) S. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells

(2009) Madhavi Billam et al.   BREAST CANCER RESEARCH AND TREATMENT

The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype

(2009) Hany Onsy Habashy et al.   BREAST CANCER RESEARCH AND TREATMENT

Histone deacetylase inhibitor induced modulation of anti-estrogen therapy

(2009) Scott Thomas et al.   CANCER LETTERS

Inhibition of SIRT1 deacetylase suppresses estrogen receptor signaling

(2009) Y. Yao et al.   CARCINOGENESIS

Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13

(2009) Khairul I. Ansari et al.   FEBS Journal

Function of Histone Deacetylase 6 as a Cofactor of Nuclear Receptor Coregulator LCoR

(2009) Ana Palijan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirement of Histone Methyltransferase SMYD3 for Estrogen Receptor-mediated Transcription

(2009) Hyunjung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Deacetylase 7 and FoxA1 in Estrogen-Mediated Repression of RPRM

(2009) S. Malik et al.   MOLECULAR AND CELLULAR BIOLOGY

Functional Connection between Deimination and Deacetylation of Histones

(2009) H. Denis et al.   MOLECULAR AND CELLULAR BIOLOGY

Estrogen Receptor α (ERα) Mediates Stimulatory Effects of Estrogen onAromatase(CYP19) Gene Expression in Human Placenta

(2009) Premlata Kumar et al.   MOLECULAR ENDOCRINOLOGY

Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing

(2009) Celia J. Webby et al.   SCIENCE

Protein arginine methylation in estrogen signaling and estrogen-related cancers

(2009) Catherine Teyssier et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells

(2008) Hideo Watanabe et al.   Cancer Cell International

CARM1 Regulates Estrogen-Stimulated Breast Cancer Growth through Up-regulation of E2F1

(2008) S. Frietze et al.   CANCER RESEARCH

Protein Phosphatase 1, Protein Phosphatase 2A, and Calcineurin Play a Role in Estrogen-Mediated Neuroprotection

(2008) Kun Don Yi et al.   ENDOCRINOLOGY

ERα negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor

(2008) Jiang Fan et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Essential Phosphatases and a Phospho-Degron Are Critical for Regulation of SRC-3/AIB1 Coactivator Function and Turnover

(2008) Chao Li et al.   MOLECULAR CELL

Nuclear and Extranuclear Pathway Inputs in the Regulation of Global Gene Expression by Estrogen Receptors

(2008) Zeynep Madak-Erdogan et al.   MOLECULAR ENDOCRINOLOGY

Downregulation of Histone H3 Lysine 9 Methyltransferase G9a Induces Centrosome Disruption and Chromosome Instability in Cancer Cells

(2008) Yutaka Kondo et al.   PLoS One

DNA Oxidation as Triggered by H3K9me2 Demethylation Drives Estrogen-Induced Gene Expression

(2008) B. Perillo et al.   SCIENCE

Histone deacetylase inhibitor SAHA induces ERα degradation in breast cancer MCF-7 cells by CHIP-mediated ubiquitin pathway and inhibits survival signaling

(2007) Xin Yi et al.   BIOCHEMICAL PHARMACOLOGY