Inhibitory Effect of a γ-Tocopherol-Rich Mixture of Tocopherols on the Formation and Growth of LNCaP Prostate Tumors in Immunodeficient Mice

Summary: Gamma- and delta-tocopherols in vitamin E have been shown to inhibit carcinogenesis in animal models, but their effects in humans remain uncertain. This pilot study found that supplementation with gamma-T-rich vitamin E increased levels of gamma-T and delta-T in prostate tissue, suggesting potential benefits for cancer prevention.

Summary: This study investigates the stability and antioxidant potential of α-tocopherol and γ-oryzanol at different concentrations. The results show that the addition of minor constituents increases the particle size and decreases lipolysis extent. Oxygen radical absorption capacity exhibits good antioxidant activity in the small intestine and micelles, while the cellular antioxidant activity results indicate unsatisfactory antioxidant activity in cells.

Summary: The study found that a bioactive peptide-rich salmon protein hydrolysate can enhance the anti-proliferative effect of bicalutamide on prostate cancer cells, potentially through modulating iron homeostasis mechanisms.