Natural Killer T Cells Subsets in Cancer, Functional Defects in Prostate Cancer and Implications for Immunotherapy

Developing understanding of the roles of CD1d-restricted T cell subsets in cancer: Reversing tumor-induced defects

(2011) Mark A. Exley et al.   CLINICAL IMMUNOLOGY

Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

(2011) Sandrine Aspeslagh et al.   EMBO JOURNAL

A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen–recognition properties

(2011) Adam P Uldrich et al.   NATURE IMMUNOLOGY

Immunotherapy with Cytokine-Induced Killer Cells in Metastatic Renal Cell Carcinoma

(2010) Xiaosan Su et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection

(2010) Famke L. Schneiders et al.   CLINICAL IMMUNOLOGY

Cytokine dependent and independent iNKT cell activation

(2010) Emma C. Reilly et al.   CYTOKINE

Dendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patients after surgery

(2010) Hui Li et al.   CYTOTHERAPY

Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC)

(2010) C. Hontscha et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

iNKT Cells Control Mouse Spontaneous Carcinoma Independently of Tumor-Specific Cytotoxic T Cells

(2010) Matteo Bellone et al.   PLoS One

Defective NKT Cell Activation by CD1d+ TRAMP Prostate Tumor Cells Is Corrected by Interleukin-12 with alpha-Galactosylceramide

(2010) Michael Nowak et al.   PLoS One

Combination therapy ofin vitro-expanded natural killer T cells and α-galactosylceramide-pulsed antigen-presenting cells in patients with recurrent head and neck carcinoma

(2009) Naoki Kunii et al.   CANCER SCIENCE

Cytokine-induced killer cells are terminallydifferentiated activated CD8 cytotoxic T-EMRA lymphocytes

(2009) Marta Franceschetti et al.   EXPERIMENTAL HEMATOLOGY

A Phase I-II Study of  -Galactosylceramide-Pulsed IL-2/GM-CSF-Cultured Peripheral Blood Mononuclear Cells in Patients with Advanced and Recurrent Non-Small Cell Lung Cancer

(2009) S. Motohashi et al.   JOURNAL OF IMMUNOLOGY

Regulation of multiple myeloma survival and progression by CD1d

(2008) E. Spanoudakis et al.   BLOOD

Inflammation-associated lysophospholipids as ligands for CD1d-restricted T cells in human cancer

(2008) D. H. Chang et al.   BLOOD

Type I NKT cells protect (and type II NKT cells suppress) the host's innate antitumor immune response to a B-cell lymphoma

(2008) G. J. Renukaradhya et al.   BLOOD

A novel immunoregulatory axis of NKT cell subsets regulating tumor immunity

(2008) Jay A. Berzofsky et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Characterization of the recognition and functional heterogeneity exhibited by cytokine-induced killer cell subsets against acute myeloid leukaemia target cell

(2008) Yeh C. Linn et al.   IMMUNOLOGY

Dendritic cells transduced with a PSMA-encoding adenovirus and cocultured with autologous cytokine-induced lymphocytes induce a specific and strong immune response against prostate cancer cells

(2008) Kebing Wang et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS