Colon Cancer Stem Cells: Bench-to-Bedside—New Therapeutical Approaches in Clinical Oncology for Disease Breakdown

Notch: Implications of endogenous inhibitors for therapy

(2010) Ivan Dikic et al.   BIOESSAYS

Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized

(2010) Elsa Quintana et al.   CANCER CELL

The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation

(2010) K. Kemper et al.   CANCER RESEARCH

Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer

(2010) Hiroshi Uchida et al.   CANCER SCIENCE

Current progress in γδ T-cell biology

(2010) Jianlei Hao et al.   Cellular & Molecular Immunology

Bone Morphogenetic Protein 4 Induces Differentiation of Colorectal Cancer Stem Cells and Increases Their Response to Chemotherapy in Mice

(2010) Ylenia Lombardo et al.   GASTROENTEROLOGY

Cancer stem cells: problems for therapy?

(2010) Malcolm R Alison et al.   JOURNAL OF PATHOLOGY

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Cancer stem cells at the crossroads of current cancer therapy failures—Radiation oncology perspective

(2010) Ulrike Koch et al.   SEMINARS IN CANCER BIOLOGY

Prognostic Significance of the Cancer Stem Cell Markers CD133, CD44, and CD166 in Colorectal Cancer

(2009) David Horst et al.   CANCER INVESTIGATION

Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis

(2009) E. H. Huang et al.   CANCER RESEARCH

DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency

(2009) Timothy Hoey et al.   Cell Stem Cell

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

(2009) Frédéric Varnat et al.   EMBO Molecular Medicine

CD133 and nuclear β-catenin: The marker combination to detect high risk cases of low stage colorectal cancer

(2009) David Horst et al.   EUROPEAN JOURNAL OF CANCER

Efficient Killing of Human Colon Cancer Stem Cells by    T Lymphocytes

(2009) M. Todaro et al.   JOURNAL OF IMMUNOLOGY

Colon cancer stem cells

(2009) Lucia Ricci-Vitiani et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Polycomb group protein Bmi1 expression in colon cancers predicts the survival

(2009) Jianjun Du et al.   MEDICAL ONCOLOGY

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

(2009) Chen Zhao et al.   NATURE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

(2009) Eric Van Cutsem et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of Mammary Stem/Progenitor Cells by PTEN/Akt/β-Catenin Signaling

(2009) Hasan Korkaya et al.   PLOS BIOLOGY

CD133 expression is an independent prognostic marker for low survival in colorectal cancer

(2008) D Horst et al.   BRITISH JOURNAL OF CANCER

Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

(2008) Christine Dierks et al.   CANCER CELL

Significance of CD90+ Cancer Stem Cells in Human Liver Cancer

(2008) Zhen Fan Yang et al.   CANCER CELL

Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells

(2008) M. G. Francipane et al.   CANCER RESEARCH

First-line combination treatment of colorectal cancer with hepatic metastases: Choosing a targeted agent

(2008) Heinz-Josef Lenz   CANCER TREATMENT REVIEWS

Cancer stem cells – old concepts, new insights

(2008) L Vermeulen et al.   CELL DEATH AND DIFFERENTIATION

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

(2008) L. Du et al.   CLINICAL CANCER RESEARCH

Human Colon Cancer Stem Cells: A New Paradigm in Gastrointestinal Oncology

(2008) Bruce M. Boman et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma

(2008) Ganapati V. Hegde et al.   MOLECULAR CANCER THERAPEUTICS

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE

Bmi1 is expressed in vivo in intestinal stem cells

(2008) Eugenio Sangiorgi et al.   NATURE GENETICS