The Nrf1 and Nrf2 Balance in Oxidative Stress Regulation and Androgen Signaling in Prostate Cancer Cells

The radiation response of androgen-refractory prostate cancer cell line C4-2 derived from androgen-sensitive cell line LNCaP

(2010) Bang-Xiang Xie et al.   ASIAN JOURNAL OF ANDROLOGY

Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species

(2010) Padma Sandeep Koka et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth

(2010) P. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells

(2010) Senthil K. Radhakrishnan et al.   MOLECULAR CELL

Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails

(2010) Y Niu et al.   ONCOGENE

Key targets of hormonal treatment of prostate cancer. Part 1: the androgen receptor and steroidogenic pathways

(2009) André N. Vis et al.   BJU INTERNATIONAL

Oxidative stress in prostate cancer

(2009) Lakshmipathi Khandrika et al.   CANCER LETTERS

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice

(2009) Melinda S. Yates et al.   CARCINOGENESIS

Molecular biology of androgen-independent prostate cancer: the role of the androgen receptor pathway

(2009) Begoña Mellado et al.   Clinical & Translational Oncology

Androgen Receptor Roles in Spermatogenesis and Fertility: Lessons from Testicular Cell-Specific Androgen Receptor Knockout Mice

(2009) Ruey-Sheng Wang et al.   ENDOCRINE REVIEWS

Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of testosterone and dihydrotestosterone from dehydroepiandrosterone

(2009) Atsushi Mizokami et al.   ENDOCRINE-RELATED CANCER

Upregulation of manganese superoxide dismutase (SOD2) is a common pathway for neuroendocrine differentiation in prostate cancer cells

(2009) Isabel Quirós et al.   INTERNATIONAL JOURNAL OF CANCER

The 26 S Proteasome: From Basic Mechanisms to Drug Targeting

(2009) Ami Navon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin and thioredoxin reductase influence estrogen receptor α-mediated gene expression in human breast cancer cells

(2009) Abhi K Rao et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Prx1 Enhances Androgen Receptor Function in Prostate Cancer Cells by Increasing Receptor Affinity to Dihydrotestosterone

(2009) R. R. Chhipa et al.   MOLECULAR CANCER RESEARCH

Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1α levels contribute to emergence of an aggressive phenotype in prostate cancer

(2009) L Khandrika et al.   ONCOGENE

Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

(2009) Madhurima Biswas et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Castration-resistant prostate cancer: Targeting androgen metabolic pathways in recurrent disease

(2009) Elahe A. Mostaghel et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

The Dual Functions of Thiol-Based Peroxidases in H2O2 Scavenging and Signaling

(2008) Simon Fourquet et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

(2008) Masuko Ushio-Fukai et al.   CANCER LETTERS

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

The Nuclear Factor- B Pathway Controls the Progression of Prostate Cancer to Androgen-Independent Growth

(2008) R. J. Jin et al.   CANCER RESEARCH

Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer

(2008) J. A. Locke et al.   CANCER RESEARCH

Hypoxia in prostate cancer: A powerful shield against tumour destruction?

(2008) L. Marignol et al.   CANCER TREATMENT REVIEWS

Increased expression of Nrf2/ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells

(2008) Sang Kyum Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCɛ signaling axis in pulmonary artery smooth muscle cells

(2008) R RATHORE et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival

(2008) Tadahisa Shono et al.   INTERNATIONAL JOURNAL OF CANCER

Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes

(2008) Makiko Ohtsuji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Irreversible Oxidation of the Active-site Cysteine of Peroxiredoxin to Cysteine Sulfonic Acid for Enhanced Molecular Chaperone Activity

(2008) Jung Chae Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of Nrf2 in increased reactive oxygen species and DNA damage in prostate tumorigenesis

(2008) D A Frohlich et al.   ONCOGENE

Dual roles of Nrf2 in cancer

(2008) A LAU et al.   PHARMACOLOGICAL RESEARCH

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA

The role of metallothionein in oncogenesis and cancer prognosis

(2008) Mie Ø. Pedersen et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Agents used for chemoprevention of prostate cancer may influence PSA secretion independently of cell growth in the LNCaP model of human prostate cancer progression

(2008) Daniel Peternac et al.   PROSTATE

JunD mediates androgen-induced oxidative stress in androgen dependent LNCaP human prostate cancer cells

(2008) Farideh Mehraein-Ghomi et al.   PROSTATE

Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults

(2007) W OSBURN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH