Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis (cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

Title
Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis (cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action
Authors
Keywords
Cysteine targeting, Keap1, NQO1, Nrf2, Reversible covalent drug
Journal
Publisher
Elsevier BV
Online
2015-08-09
DOI
10.1016/j.bbrc.2015.08.016

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