Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age

Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

(2013) Amanda Boyd et al.   ACTA NEUROPATHOLOGICA

Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo

(2013) Tim Czopka et al.   DEVELOPMENTAL CELL

Promoting Remyelination in Multiple Sclerosis—Recent Advances

(2013) E. Jolanda Münzel et al.   DRUGS

Increased radial glia quiescence, decreased reactivation upon injury and unaltered neuroblast behavior underlie decreased neurogenesis in the aging zebrafish telencephalon

(2013) Kathrin Edelmann et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Signaling through ERK1/2 Controls Myelin Thickness during Myelin Repair in the Adult Central Nervous System

(2013) S. L. Fyffe-Maricich et al.   JOURNAL OF NEUROSCIENCE

Generation of demyelination models by targeted ablation of oligodendrocytes in the zebrafish CNS

(2013) Ah-Young Chung et al.   MOLECULES AND CELLS

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Remyelination reporter reveals prolonged refinement of spontaneously regenerated myelin

(2013) B. E. Powers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rejuvenation of Regeneration in the Aging Central Nervous System

(2012) Julia M. Ruckh et al.   Cell Stem Cell

Increasing Internodal Distance in Myelinated Nerves Accelerates Nerve Conduction to a Flat Maximum

(2012) Lai Man N. Wu et al.   CURRENT BIOLOGY

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

A culture system to study oligodendrocyte myelination processes using engineered nanofibers

(2012) Seonok Lee et al.   NATURE METHODS

Late motor decline after accomplished remyelination: Impact for progressive multiple sclerosis

(2011) Natalia Manrique-Hoyos et al.   ANNALS OF NEUROLOGY

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis

(2011) Jessica L. Zambonin et al.   BRAIN

Individual axons regulate the myelinating potential of single oligodendrocytes in vivo

(2011) R. G. Almeida et al.   DEVELOPMENT

Adult neurogenesis and brain regeneration in zebrafish

(2011) Caghan Kizil et al.   Developmental Neurobiology

Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish

(2011) Eva Jolanda Münzel et al.   GLIA

Axonally Derived Neuregulin-1 Is Required for Remyelination and Regeneration after Nerve Injury in Adulthood

(2011) F. R. Fricker et al.   JOURNAL OF NEUROSCIENCE

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

(2010) Emily P. Harrington et al.   ANNALS OF NEUROLOGY

Retinoid X receptor gamma signaling accelerates CNS remyelination

(2010) Jeffrey K Huang et al.   NATURE NEUROSCIENCE

Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

(2010) Clare E. Buckley et al.   NEUROPHARMACOLOGY

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression ofCnp1

(2009) Julia M. Edgar et al.   GLIA

Remyelination capacity of the MS brain decreases with disease chronicity

(2009) T. Goldschmidt et al.   NEUROLOGY

nkx2.2a promotes specification and differentiation of a myelinating subset of oligodendrocyte lineage cells in zebrafish

(2009) Sarah Kucenas et al.   Neuron Glia Biology

Extensive remyelination of the CNS leads to functional recovery

(2009) I. D. Duncan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutively Active Akt Induces Enhanced Myelination in the CNS

(2008) A. I. Flores et al.   JOURNAL OF NEUROSCIENCE

Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System

(2008) Bastian G. Brinkmann et al.   NEURON