Accumulation of 2-hydroxyglutarate in gliomas correlates with survival: a study by 3.0-tesla magnetic resonance spectroscopy
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Title
Accumulation of 2-hydroxyglutarate in gliomas correlates with survival: a study by 3.0-tesla magnetic resonance spectroscopy
Authors
Keywords
Glioma, MRS, 2-hydroxyglutarate, IDH mutation, Prognostic marker
Journal
Acta Neuropathologica Communications
Volume 2, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-11-06
DOI
10.1186/s40478-014-0158-y
References
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Note: Only part of the references are listed.- 2-Hydroxyglutarate as a Magnetic Resonance Biomarker for Glioma Subtyping
- (2014) Morteza Esmaeili et al. Translational Oncology
- Autophagy and oxidative stress in gliomas with IDH1 mutations
- (2013) Misty R. Gilbert et al. ACTA NEUROPATHOLOGICA
- Rapid detection of IDH2 (R140Q and R172K) mutations in acute myeloid leukemia
- (2013) Saquib Ashraf et al. ANNALS OF HEMATOLOGY
- Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate
- (2013) Ovidiu C. Andronesi et al. JOURNAL OF CLINICAL INVESTIGATION
- MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
- (2013) Atsushi Terunuma et al. JOURNAL OF CLINICAL INVESTIGATION
- cMYC expression in infiltrating gliomas: associations with IDH1 mutations, clinicopathologic features and outcome
- (2013) Yazmin Odia et al. JOURNAL OF NEURO-ONCOLOGY
- IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection
- (2013) Jason Beiko et al. NEURO-ONCOLOGY
- An IDH1 mutation inhibits growth of glioma cells via GSH depletion and ROS generation
- (2013) Jinlong Shi et al. NEUROLOGICAL SCIENCES
- A comparative study of short- and long-TE1H MRS at 3 T forin vivodetection of 2-hydroxyglutarate in brain tumors
- (2013) Changho Choi et al. NMR IN BIOMEDICINE
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- The Emerging Role of D-2-Hydroxyglutarate as an Oncometabolite in Hematolymphoid and Central Nervous System Neoplasms
- (2013) Dinesh Rakheja et al. Frontiers in Oncology
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
- (2012) Peppi Koivunen et al. NATURE
- 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas
- (2012) Changho Choi et al. NATURE MEDICINE
- Detection of 2-hydroxyglutaric acid in vivo by proton magnetic resonance spectroscopy in U87 glioma cells overexpressing isocitrate dehydrogenase-1 mutation
- (2012) J. Lazovic et al. NEURO-ONCOLOGY
- Detection of 2-Hydroxyglutarate in IDH-Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy
- (2012) O. C. Andronesi et al. Science Translational Medicine
- Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas
- (2012) A. Elkhaled et al. Science Translational Medicine
- Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo
- (2012) Janeta Popovici-Muller et al. ACS Medicinal Chemistry Letters
- Detection of 2-Hydroxyglutarate in Formalin-Fixed Paraffin-Embedded Glioma Specimens by Gas Chromatography/Mass Spectrometry
- (2011) Felix Sahm et al. BRAIN PATHOLOGY
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
- (2011) Rasheduzzaman Chowdhury et al. EMBO REPORTS
- Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy
- (2011) Whitney B. Pope et al. JOURNAL OF NEURO-ONCOLOGY
- Isocitrate dehydrogenase mutations may be a protective mechanism in glioma patients
- (2011) Jian Zhu et al. MEDICAL HYPOTHESES
- Brainstem metabolites in multiple system atrophy of cerebellar type: 3.0-T magnetic resonance spectroscopy study
- (2011) Yuhei Takado et al. MOVEMENT DISORDERS
- Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
- (2011) Z. J. Reitman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1
- (2010) M. J. Seltzer et al. CANCER RESEARCH
- Monoclonal antibody specific for IDH1 R132H mutation
- (2009) David Capper et al. ACTA NEUROPATHOLOGICA
- A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation
- (2009) Yukinari Kato et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
- (2009) Ping Gao et al. NATURE
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
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