Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies

Rasmussen's encephalitis: clinical features, pathobiology, and treatment advances

(2014) Sophia Varadkar et al.   LANCET NEUROLOGY

mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis

(2013) Shireena A. Yasin et al.   ACTA NEUROPATHOLOGICA

TORC1-dependent epilepsy caused by acute biallelicTsc1deletion in adult mice

(2013) Elisabeth Abs et al.   ANNALS OF NEUROLOGY

International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: A Task Force report from the ILAE Commission on Diagnostic Methods

(2013) Ingmar Blümcke et al.   EPILEPSIA

Long-term effect of everolimus on epilepsy and growth in children under 3 years of age treated for subependymal giant cell astrocytoma associated with tuberous sclerosis complex

(2013) Katarzyna Kotulska et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

A critical review of mTOR inhibitors and epilepsy: from basic science to clinical trials

(2013) Michael Wong   Expert Review of Neurotherapeutics

mTOR signaling for biological control and cancer

(2013) Anya Alayev et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PI3K-Akt Signaling Activates mTOR-Mediated Epileptogenesis in Organotypic Hippocampal Culture Model of Post-Traumatic Epilepsy

(2013) Y. Berdichevsky et al.   JOURNAL OF NEUROSCIENCE

Role of the mTOR signaling pathway in epilepsy

(2013) Xiang-Fei Meng et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

De novo mutations in epileptic encephalopathies

(2013) et al.   NATURE

Focal malformations of cortical development: New vistas for molecular pathogenesis

(2013) K.-C. Lim et al.   NEUROSCIENCE

Detection of human papillomavirus in human focal cortical dysplasia type IIB

(2012) Julie Chen et al.   ANNALS OF NEUROLOGY

Neuropathology of the blood–brain barrier and pharmaco-resistance in human epilepsy

(2012) Joan Y. W. Liu et al.   BRAIN

Good interobserver and intraobserver agreement in the evaluation of the new ILAE classification of focal cortical dysplasias

(2012) Roland Coras et al.   EPILEPSIA

The mTOR pathway is activated in glial cells in mesial temporal sclerosis

(2012) Alexander A. Sosunov et al.   EPILEPSIA

Excessive Activation of mTOR in Postnatally Generated Granule Cells Is Sufficient to Cause Epilepsy

(2012) Raymund Y.K. Pun et al.   NEURON

Mapping the Spatio-Temporal Pattern of the Mammalian Target of Rapamycin (mTOR) Activation in Temporal Lobe Epilepsy

(2012) Long-Ze Sha et al.   PLoS One

GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease

(2012) Willem Kamphuis et al.   PLoS One

mTOR: on target for novel therapeutic strategies in the nervous system

(2012) Kenneth Maiese et al.   TRENDS IN MOLECULAR MEDICINE

Mammalian target of rapamycin (mTOR) activation in focal cortical dysplasia and related focal cortical malformations

(2011) Michael Wong   EXPERIMENTAL NEUROLOGY

A pulse rapamycin therapy for infantile spasms and associated cognitive decline

(2011) Emmanuel Raffo et al.   NEUROBIOLOGY OF DISEASE

Therapeutic role of mammalian target of rapamycin (mTOR) inhibition in preventing epileptogenesis

(2011) Sharon S. McDaniel et al.   NEUROSCIENCE LETTERS

mTOR: A pathogenic signaling pathway in developmental brain malformations

(2011) Peter B. Crino   TRENDS IN MOLECULAR MEDICINE

The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission1

(2010) Ingmar Blümcke et al.   EPILEPSIA

Early Progenitor Cell Marker Expression Distinguishes Type II From Type I Focal Cortical Dysplasias

(2010) Ksenia A. Orlova et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A comprehensive map of the mTOR signaling network

(2010) Etienne Caron et al.   Molecular Systems Biology

Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy

(2010) Xiaoxing Huang et al.   NEUROBIOLOGY OF DISEASE

Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR

(2010) Atsushi Sato et al.   NEUROSCIENCE LETTERS

Balloon cells in the dentate gyrus in hippocampal sclerosis associated with non-herpetic acute limbic encephalitis

(2010) Hiroaki Miyahara et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Pi3K-mTOR Signaling and AMOG Expression in Epilepsy-associated Glioneuronal Tumors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Temporal Lobe Sclerosis Associated With Hippocampal Sclerosis in Temporal Lobe Epilepsy: Neuropathological Features

(2009) Maria Thom et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Inhibition of the Mammalian Target of Rapamycin Signaling Pathway Suppresses Dentate Granule Cell Axon Sprouting in a Rodent Model of Temporal Lobe Epilepsy

(2009) P. S. Buckmaster et al.   JOURNAL OF NEUROSCIENCE

Dual pathology in Rasmussen's encephalitis: A study of seven cases and review of the literature

(2009) Hidehiro Takei et al.   NEUROPATHOLOGY

Expression patterns of glial fibrillary acidic protein (GFAP)-delta in epilepsy-associated lesional pathologies

(2009) L. Martinian et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Balloon cells associated with granule cell dispersion in the dentate gyrus in hippocampal sclerosis

(2008) M. Thom et al.   ACTA NEUROPATHOLOGICA

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex

(2008) Ling-Hui Zeng et al.   ANNALS OF NEUROLOGY

Recent advances in neurobiology of Tuberous Sclerosis Complex

(2008) Valerio Napolioni et al.   BRAIN & DEVELOPMENT

Balloon cells and dysmorphic neurons in the hippocampus associated with epileptic amnesic syndrome: A case report

(2008) Se Hoon Kim et al.   EPILEPSIA

Neurogenesis in the human hippocampus and its relevance to temporal lobe epilepsies

(2008) Florian A. Siebzehnrubl et al.   EPILEPSIA

The RSK family of kinases: emerging roles in cellular signalling

(2008) Rana Anjum et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY