A neuronal function of the tumor suppressor protein merlin

In Vivo Functional Analysis of the Human NF2 Tumor Suppressor Gene in Drosophila

(2014) Heather S. Gavilan et al.   PLoS One

Neuronal merlin influences ERBB2 receptor expression on Schwann cells through neuregulin 1 type III signalling

(2013) Alexander Schulz et al.   BRAIN

Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2

(2013) Feng Yin et al.   CELL

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

(2013) A. Lavado et al.   DEVELOPMENT

Membrane domain organization of myelinated axons requires βII spectrin

(2013) Chuansheng Zhang et al.   JOURNAL OF CELL BIOLOGY

Merlin isoform 2 in neurofibromatosis type 2–associated polyneuropathy

(2013) Alexander Schulz et al.   NATURE NEUROSCIENCE

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus

(2012) Wei Li et al.   EMBO REPORTS

Distinct overlapping sequences at the carboxy-terminus of merlin regulate its tumour suppressor and morphogenic activity

(2012) Minja Laulajainen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Accumulation of non-compressive fascicular lesions underlies NF2 polyneuropathy

(2012) P. Bäumer et al.   JOURNAL OF NEUROLOGY

What Is the Site of Origin of Cochleovestibular Schwannomas?

(2011) Christof Roosli et al.   AUDIOLOGY AND NEURO-OTOLOGY

FERM Domain Phosphoinositide Binding Targets Merlin to the Membrane and Is Essential for Its Growth-Suppressive Function

(2011) T. Mani et al.   MOLECULAR AND CELLULAR BIOLOGY

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus

(2010) Wei Li et al.   CELL

Merlin Inhibits Neurite Outgrowth in the CNS

(2010) A. Schulz et al.   JOURNAL OF NEUROSCIENCE

Schwannomin/merlin promotes Schwann cell elongation and influences myelin segment length

(2010) Courtney Thaxton et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma

(2010) S. Ammoun et al.   NEURO-ONCOLOGY

Neurofibromatosis 2 with peripheral neuropathies: Electrophysiological, pathological and genetic studies of a Taiwanese family

(2010) Hung-Chou Kuo et al.   NEUROPATHOLOGY

Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancer

(2010) Y Zhan et al.   ONCOGENE

Rates of loss of heterozygosity and mitotic recombination in NF2 schwannomas, sporadic vestibular schwannomas and schwannomatosis schwannomas

(2010) K D Hadfield et al.   ONCOGENE

Consensus Recommendations to Accelerate Clinical Trials for Neurofibromatosis Type 2

(2009) D. G. Evans et al.   CLINICAL CANCER RESEARCH

Identification of Erythrocyte p55/MPP1 as a Binding Partner of NF2 Tumor Suppressor Protein/Merlin

(2009) Pil-Soo Seo et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Neurofibromatosis type 2

(2009) Ashok R Asthagiri et al.   LANCET

NF2/Merlin Is a Novel Negative Regulator of mTOR Complex 1, and Activation of mTORC1 Is Associated with Meningioma and Schwannoma Growth

(2009) M. F. James et al.   MOLECULAR AND CELLULAR BIOLOGY

Merlin and the ERM proteins – regulators of receptor distribution and signaling at the cell cortex

(2009) Andrea I. McClatchey et al.   TRENDS IN CELL BIOLOGY

The Loss of Nf1 Transiently Promotes Self-Renewal but Not Tumorigenesis by Neural Crest Stem Cells

(2008) Nancy M. Joseph et al.   CANCER CELL

Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin

(2008) Junji Yamauchi et al.   EXPERIMENTAL CELL RESEARCH

NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F

(2008) S. Parrinello et al.   GENES & DEVELOPMENT

Molecular domains of myelinated axons in the peripheral nervous system

(2008) James L. Salzer et al.   GLIA

Tumor Suppressor Schwannomin/Merlin Is Critical for the Organization of Schwann Cell Contacts in Peripheral Nerves

(2008) N. Denisenko et al.   JOURNAL OF NEUROSCIENCE

Review of the Multiple Aspects of Neurofilament Functions, and their Possible Contribution to Neurodegeneration

(2008) Rodolphe Perrot et al.   MOLECULAR NEUROBIOLOGY

Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas

(2008) D Lallemand et al.   ONCOGENE

The ErbB Inhibitors Trastuzumab and Erlotinib Inhibit Growth of Vestibular Schwannoma Xenografts in Nude Mice

(2008) J. Jason Clark et al.   OTOLOGY & NEUROTOLOGY

Magic but treatable? Tumours due to loss of Merlin

(2007) C. O. Hanemann   BRAIN