Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons

DNA Damage Triggers Golgi Dispersal via DNA-PK and GOLPH3

(2014) Suzette E. Farber-Katz et al.   CELL

Human Diseases Associated with Form and Function of the Golgi Complex

(2013) Mariana Bexiga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

(2013) Myrrhe van Spronsen et al.   NEURON

Increased neuronal activity fragments the Golgi complex

(2013) Desiree A. Thayer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TRK-Fused Gene Is Mutated in Hereditary Motor and Sensory Neuropathy with Proximal Dominant Involvement

(2012) Hiroyuki Ishiura et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis

(2012) Manal A. Farg et al.   HUMAN MOLECULAR GENETICS

Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats

(2012) Cao Huang et al.   HUMAN MOLECULAR GENETICS

XBP1 depletion precedes ubiquitin aggregation and Golgi fragmentation in TDP-43 transgenic rats

(2012) Jianbin Tong et al.   JOURNAL OF NEUROCHEMISTRY

BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures

(2012) Daniël Splinter et al.   MOLECULAR BIOLOGY OF THE CELL

Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation

(2011) Hidefumi Ito et al.   ACTA NEUROPATHOLOGICA

Control of Organelle Size: The Golgi Complex

(2011) Debrup Sengupta et al.   Annual Review of Cell and Developmental Biology

New components of the Golgi matrix

(2011) Yi Xiang et al.   CELL AND TISSUE RESEARCH

A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

(2011) A. Acevedo-Arozena et al.   Disease Models & Mechanisms

Spinal Inhibitory Interneuron Pathology Follows Motor Neuron Degeneration Independent of Glial Mutant Superoxide Dismutase 1 Expression in SOD1-ALS Mice

(2011) Mehdi Hossaini et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states

(2011) Mercedes Prudencio et al.   Molecular Neurodegeneration

Mitochondria: The Next (Neurode)Generation

(2011) Eric A. Schon et al.   NEURON

Selective Neuronal Vulnerability in Neurodegenerative Diseases: from Stressor Thresholds to Degeneration

(2011) Smita Saxena et al.   NEURON

Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice

(2010) Monique C. de Waard et al.   ACTA NEUROPATHOLOGICA

Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form

(2010) Aaron Kerman et al.   ACTA NEUROPATHOLOGICA

Amyotrophic Lateral Sclerosis Pathogenesis: A Journey Through the Secretory Pathway

(2010) Melissa Nassif et al.   ANTIOXIDANTS & REDOX SIGNALING

Should the word ‘dementia’ be forgotten?

(2010) Kurt A. Jellinger   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis

(2010) Nichole A. Reyes et al.   JOURNAL OF CLINICAL INVESTIGATION

TGN golgins, Rabs and cytoskeleton: regulating the Golgi trafficking highways

(2010) Bruno Goud et al.   TRENDS IN CELL BIOLOGY

Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes

(2010) Casper C. Hoogenraad et al.   PLOS BIOLOGY

Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

(2009) Hristelina Ilieva et al.   JOURNAL OF CELL BIOLOGY

Oxysterol Binding Protein–related Protein 9 (ORP9) Is a Cholesterol Transfer Protein That Regulates Golgi Structure and Function

(2009) Mike Ngo et al.   MOLECULAR BIOLOGY OF THE CELL

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

(2009) Smita Saxena et al.   NATURE NEUROSCIENCE

Golgins and GRASPs: Holding the Golgi together

(2009) Irene Barinaga-Rementeria Ramirez et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Death by Committee: Organellar Trafficking and Communication in Apoptosis

(2009) Joseph E. Aslan et al.   TRAFFIC

A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice

(2008) Eva Teuling et al.   HUMAN MOLECULAR GENETICS

Golgi apparatus and neurodegenerative diseases

(2008) Jie Fan et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Preferential motor unit loss in the SOD1G93Atransgenic mouse model of amyotrophic lateral sclerosis

(2008) J. Hegedus et al.   JOURNAL OF PHYSIOLOGY-LONDON

Anterior horn cells with abnormal TDP-43 immunoreactivities show fragmentation of the Golgi apparatus in ALS

(2008) Yukio Fujita et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A Golgi fragmentation pathway in neurodegeneration

(2007) Saya Nakagomi et al.   NEUROBIOLOGY OF DISEASE