Strategies for osteochondral repair: Focus on scaffolds

Medium-Term Outcome of Mosaicplasty for Grade III-IV Cartilage Defects of the Knee

(2016) Maria Mercedes Reverte-Vinaixa et al.   Journal of Orthopaedic Surgery

In vitro chondrogenesis and in vivo repair of osteochondral defect with human induced pluripotent stem cells

(2014) Ji-Yun Ko et al.   BIOMATERIALS

Bi-layer collagen/microporous electrospun nanofiber scaffold improves the osteochondral regeneration

(2013) Shufang Zhang et al.   Acta Biomaterialia

No Effect of Hole Geometry in Microfracture for Talar Osteochondral Defects

(2013) Aimee Claire Kok et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

A cell-free nanofiber composite scaffold regenerated osteochondral defects in miniature pigs

(2013) Eva Filová et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Cartilage repair by local delivery of transforming growth factor-β1 or bone morphogenetic protein-2 from a novel, segmented polyurethane/polylactic-co -glycolic bilayered scaffold

(2013) Ricardo Reyes et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Osteochondral tissue regeneration using a bilayered composite hydrogel with modulating dual growth factor release kinetics in a rabbit model

(2013) Kyobum Kim et al.   JOURNAL OF CONTROLLED RELEASE

Cartilage repair of experimentally 11 induced osteochondral defects in New Zealand White rabbits

(2013) C Aulin et al.   LABORATORY ANIMALS

Repair of Large Osteochondral Defects With Mix-Mosaicplasty in a Goat Model

(2013) Ping Leng et al.   ORTHOPEDICS

Bone Marrow Aspiration Concentrate and Platelet Rich Plasma for Osteochondral Repair in a Porcine Osteochondral Defect Model

(2013) Marcel Betsch et al.   PLoS One

Evaluation of cartilage, synovium and adipose tissue as cellular sources for osteochondral repair

(2013) J.F. Innes et al.   VETERINARY JOURNAL

Effect of IGF-1 and Uncultured Autologous Bone-Marrow-Derived Mononuclear Cells on Repair of Osteochondral Defect in Rabbits

(2013) Ramesh Tiwary et al.   Cartilage

Chondrogenic potential of bone marrow–derived mesenchymal stem cells on a novel, auricular-shaped, nanocomposite scaffold

(2013) Kavi H Patel et al.   Journal of Tissue Engineering

Bilayered constructs aimed at osteochondral strategies: The influence of medium supplements in the osteogenic and chondrogenic differentiation of amniotic fluid-derived stem cells

(2012) Márcia T. Rodrigues et al.   Acta Biomaterialia

Biomaterial delivery of morphogens to mimic the natural healing cascade in bone

(2012) Manav Mehta et al.   ADVANCED DRUG DELIVERY REVIEWS

Naturally and synthetic smart composite biomaterials for tissue regeneration

(2012) Román A. Pérez et al.   ADVANCED DRUG DELIVERY REVIEWS

Osteochondral tissue engineering: Current strategies and challenges

(2012) Syam P. Nukavarapu et al.   BIOTECHNOLOGY ADVANCES

Effect of environmental tobacco smoke on atopic dermatitis among children in Korea

(2012) Okhee Yi et al.   ENVIRONMENTAL RESEARCH

Influence of patellofemoral articular geometry and material on mechanics of the unresurfaced patella

(2012) Clare K. Fitzpatrick et al.   JOURNAL OF BIOMECHANICS

Autologous chondrocyte implantation for osteochondral lesions in the knee using a bilayer collagen membrane and bone graft

(2012) S. Vijayan et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

Local BMP-7 release from a PLGA scaffolding-matrix for the repair of osteochondral defects in rabbits

(2012) Mi Ra Jung et al.   JOURNAL OF CONTROLLED RELEASE

Repair of an osteochondral defect by sustained delivery of BMP-2 or TGFβ1 from a bilayered alginate-PLGA scaffold

(2012) R. Reyes et al.   Journal of Tissue Engineering and Regenerative Medicine

Reconstruct large osteochondral defects of the knee with hIGF-1 gene enhanced Mosaicplasty

(2012) Ping Leng et al.   KNEE

Microfracture combined with osteochondral paste implantation was more effective than microfracture alone for full-thickness cartilage repair

(2012) Linzi Xing et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Fabrication of a bio‐inspired beta‐Tricalcium phosphate/collagen scaffold based on ceramic stereolithography and gel casting for osteochondral tissue engineering

(2012) Weiguo Bian et al.   RAPID PROTOTYPING JOURNAL

Interplay Between Local Versus Soluble Transforming Growth Factor-Beta and Fibrin Scaffolds: Role of Cells and Impact on Human Mesenchymal Stem Cell Chondrogenesis

(2012) Solvig Diederichs et al.   TISSUE ENGINEERING PART A

Dynamic Culturing of Cartilage Tissue: The Significance of Hydrostatic Pressure

(2012) Cristina Correia et al.   TISSUE ENGINEERING PART A

Microstructure and friction properties of PVA/PVP hydrogels for articular cartilage repair as function of polymerization degree and polymer concentration

(2012) Yan Shi et al.   WEAR

Hydrogel-Based Platforms for the Regeneration of Osteochondral Tissue and Intervertebral Disc

(2012) Vincenzo Guarino et al.   Polymers

In vitro chondrogenic differentiation of human adipose-derived stem cells with silk scaffolds

(2012) Hyeon Joo Kim et al.   Journal of Tissue Engineering

A short review: Recent advances in electrospinning for bone tissue regeneration

(2012) Song-Hee Shin et al.   Journal of Tissue Engineering

Autologous Osteochondral Transplantation of the Talus Partially Restores Contact Mechanics of the Ankle Joint

(2011) Ashraf M. Fansa et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffolds

(2011) Jiangning Chen et al.   BIOMATERIALS

Stratified scaffolds for osteochondral tissue engineering applications: Electrospun PDLLA nanofibre coated Bioglass®-derived foams

(2011) DM Yunos et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Electrospun nanofiber-based regeneration of cartilage enhanced by mesenchymal stem cells

(2011) Abbas Shafiee et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Osteochondral interface regeneration of the rabbit knee with macroscopic gradients of bioactive signals

(2011) Nathan H. Dormer et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Maintenance of cartilaginous gene expression on extracellular matrix derived from serially passaged chondrocytes during in vitro chondrocyte expansion

(2011) Takashi Hoshiba et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Coupling of gelatin to inner surfaces of pore walls in spongy alginate-based scaffolds facilitates the adhesion, growth and differentiation of human bone marrow mesenchymal stromal cells

(2011) Yu. A. Petrenko et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Localization of vascular endothelial growth factor during the early stages of osteochondral regeneration using a bioabsorbable synthetic polymer scaffold

(2011) Ryosuke Sakata et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Transplanted articular chondrocytes co-overexpressing IGF-I and FGF-2 stimulate cartilage repair in vivo

(2011) Patrick Orth et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

A Hydrogel-Mineral Composite Scaffold for Osteochondral Interface Tissue Engineering

(2011) Nora T. Khanarian et al.   TISSUE ENGINEERING PART A

Engineering Lubrication in Articular Cartilage

(2011) Sean M. McNary et al.   TISSUE ENGINEERING PART B-REVIEWS

Development of novel hybrid poly(l-lactide)/chitosan scaffolds using the rapid freeze prototyping technique

(2011) N Zhu et al.   Biofabrication

Bioactive Stratified Polymer Ceramic-Hydrogel Scaffold for Integrative Osteochondral Repair

(2010) Jie Jiang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation

(2010) Esther Rebollar et al.   APPLIED SURFACE SCIENCE

The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells

(2010) Chin-Yu Lin et al.   BIOMATERIALS

Toward delivery of multiple growth factors in tissue engineering

(2010) Fa-Ming Chen et al.   BIOMATERIALS

Inorganic-organic hybrid scaffolds for osteochondral regeneration

(2010) Dany J. Munoz-Pinto et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Human umbilical cord mesenchymal stromal cells in a sandwich approach for osteochondral tissue engineering

(2010) Limin Wang et al.   Journal of Tissue Engineering and Regenerative Medicine

Hybrid fixation: evaluation of a novel technique in adult osteochondritis dissecans of the knee

(2010) Francois Lintz et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: a 2-year randomised study

(2010) Erhan Basad et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Spatial regulation of human mesenchymal stem cell differentiation in engineered osteochondral constructs: effects of pre-differentiation, soluble factors and medium perfusion

(2010) W.L. Grayson et al.   OSTEOARTHRITIS AND CARTILAGE

Microscale Versus Nanoscale Scaffold Architecture for Mesenchymal Stem Cell Chondrogenesis

(2010) Shobana Shanmugasundaram et al.   TISSUE ENGINEERING PART A

Stereolithographic Bone Scaffold Design Parameters: Osteogenic Differentiation and Signal Expression

(2010) Kyobum Kim et al.   TISSUE ENGINEERING PART B-REVIEWS

The influence of structural design of PLGA/collagen hybrid scaffolds in cartilage tissue engineering

(2009) Wenda Dai et al.   BIOMATERIALS

Rapid prototyping of anatomically shaped, tissue-engineered implants for restoring congruent articulating surfaces in small joints

(2009) T. B. F. Woodfield et al.   CELL PROLIFERATION

Osteochondral autografting (mosaicplasty) in articular cartilage defects in the knee: Results at 5 to 9 years

(2009) Eirik Solheim et al.   KNEE

Osteochondral angiogenesis and increased protease inhibitor expression in OA

(2009) R.E. Fransès et al.   OSTEOARTHRITIS AND CARTILAGE

Chondroitinase ABC Treatment Results in Greater Tensile Properties of Self-Assembled Tissue-Engineered Articular Cartilage

(2009) Roman M. Natoli et al.   TISSUE ENGINEERING PART A

Engineering Orthopedic Tissue Interfaces

(2009) Peter J. Yang et al.   TISSUE ENGINEERING PART B-REVIEWS

Characteristic Complications after Autologous Chondrocyte Implantation for Cartilage Defects of the Knee Joint

(2008) Philipp Niemeyer et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

The repair of osteochondral defects using baculovirus-mediated gene transfer with de-differentiated chondrocytes in bioreactor culture

(2008) Huang-Chi Chen et al.   BIOMATERIALS

Enhancing Osteochondral Allograft Viability: Effects of Storage Media Composition

(2008) Margie S. Teng et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering

(2008) Xiaoqin Wang et al.   JOURNAL OF CONTROLLED RELEASE

Synergistic and Additive Effects of Hydrostatic Pressure and Growth Factors on Tissue Formation

(2008) Benjamin D. Elder et al.   PLoS One

Bilayered Scaffolds for Osteochondral Tissue Engineering

(2008) Timothy M. O'Shea et al.   TISSUE ENGINEERING PART B-REVIEWS