Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) in transgenic mouse models of frontotemporal lobar degeneration and Alzheimer’s disease

Highly Stabilized Curcumin Nanoparticles Tested in an In Vitro Blood–Brain Barrier Model and in Alzheimer’s Disease Tg2576 Mice

(2012) Kwok Kin Cheng et al.   AAPS Journal

Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer's disease

(2011) Qin Nie et al.   ACTA PHARMACOLOGICA SINICA

Anti-tau oligomers passive vaccination for the treatment of Alzheimer disease

(2011) Rakez Kayed   Human vaccines & immunotherapeutics

Heart complications in familial transthyretin amyloidosis: impact of age and gender

(2010) Rolf Hörnsten et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

The Hsp40 J-domain Stimulates Hsp70 When Tethered by the Client to the ATPase Domain

(2010) B. Erin Horne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells

(2010) Chu Peng Hoi et al.   PHYTOTHERAPY RESEARCH

Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

(2010) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

The Molecular Chaperone Hsp90 Modulates Intermediate Steps of Amyloid Assembly of the Parkinson-related Protein α-Synuclein

(2009) S. Fabio Falsone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

(2009) John Hardy   JOURNAL OF NEUROCHEMISTRY

Chemical Manipulation of Hsp70 ATPase Activity Regulates Tau Stability

(2009) U. K. Jinwal et al.   JOURNAL OF NEUROSCIENCE

Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

(2009) Kurt R. Brunden et al.   NATURE REVIEWS DRUG DISCOVERY

Gender-related risk of myocardial involvement in systemic amyloidosis

(2008) Claudio Rapezzi et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line

(2008) Yuanming Lu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Heat Shock Transcription Factor 1-activating Compounds Suppress Polyglutamine-induced Neurodegeneration through Induction of Multiple Molecular Chaperones

(2008) Nobuhiro Fujikake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system

(2008) Jennifer L. Hanslick et al.   NEUROBIOLOGY OF DISEASE

Higher Islet Amyloid Load in Men Than in Women With Type 2 Diabetes Mellitus

(2008) Hai-Lu Zhao et al.   PANCREAS

Amyloid oligomers in diabetic and nondiabetic human pancreas

(2008) Hai-Lu Zhao et al.   Translational Research

Extracellular heat shock protein 70 inhibits tumour necrosis factor-α induced proinflammatory mediator production in fibroblast-like synoviocytes

(2008) Xinjing Luo et al.   ARTHRITIS RESEARCH & THERAPY

Development and application of Hsp90 inhibitors

(2007) D SOLIT   DRUG DISCOVERY TODAY