Review
Medicine, Research & Experimental
Min-Rui Ding, Yan-Jie Qu, Bing Hu, Hong-Mei An
Summary: Traditional Chinese medicine can modulate multiple signal pathways related to the pathological progression of Alzheimer's disease, thereby improving cognitive impairment. In-depth research on the prevention and treatment of Alzheimer's disease with traditional Chinese medicine can provide new ideas for exploring the pathogenesis of Alzheimer's disease and developing new anti-AD drugs.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Review
Pharmacology & Pharmacy
Lei Li, Man Wang, Jikuai Chen, Juelin Chen, Yawei Wang, Minghao Zhao, Qing Song, Shuogui Xu
Summary: As global warming continues, heat waves are becoming more frequent and intense, leading to an increase in the incidence of heat stroke. Heat stroke is associated with significant morbidity and mortality, and further research is urgently needed to address this issue. Traditional Chinese medicine offers potential treatment methods, including herbal therapies and external treatments, which may provide clinical benefits and research directions for heat stroke.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Wanying Tan, Lingjun Qi, Xiaoyu Hu, Zhenghuai Tan
Summary: Alzheimer's disease is the leading cause of dementia worldwide, posing a significant economic burden on nations and families. Despite the unknown etiology and lack of effective treatments, traditional Chinese medicine has made important contributions in the battle against Alzheimer's disease. This study reviews the treatment strategies and new discoveries in traditional Chinese medicine research, which may be beneficial in the development of new drugs.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Chemistry, Medicinal
Xianfeng Liu, Xinmei Xu, Tao Zhang, Lei Xu, Honglin Tao, Yue Liu, Yi Zhang, Xianli Meng
Summary: Cardiovascular diseases are the leading cause of death worldwide, and abnormalities in cardiac fatty acid metabolism play a crucial role in their development. Traditional Chinese medicines have been found to regulate the expression of key proteins involved in fatty acid metabolism, providing a cardioprotective effect. This study systematically reviews the relationship between fatty acid metabolism disorders and four types of cardiovascular diseases, and identifies potential cardioprotective agents targeting fatty acid metabolism from traditional Chinese medicines extracts and components.
PHYTOTHERAPY RESEARCH
(2023)
Review
Medicine, Research & Experimental
Hai-Yu Zhang, Jia-Xing Tian, Feng-Mei Lian, Min Li, Wen-Ke Liu, Zhong Zhen, Jiang-Quan Liao, Xiao-Lin Tong
Summary: Traditional Chinese medicines have shown considerable effects in treating metabolic disorders by regulating gut microbiota, particularly by affecting glucose and lipid metabolism through modulating specific types of bacteria. The potential mechanisms include protection of the intestinal barrier function, modulation of metabolic endotoxemia and inflammatory responses, regulation of SCFAs, modulation of the gut-brain axis, and regulation of bile acid and tryptophan metabolism.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Review
Pharmacology & Pharmacy
Weifan Xu, Yiping Jiang, Nani Wang, Huanhuan Bai, Shengyan Xu, Tianshuang Xia, Hailiang Xin
Summary: Alzheimer's disease and osteoporosis are progressive degenerative diseases that place a significant burden on the world. They are linked to each other through a pathophysiological connection rather than one causing the other. Traditional Chinese medicine offers valuable therapies that can ameliorate symptoms and provide alternative options for treatment.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Chemistry, Medicinal
Huimei Liu, Li Zhu, Linxi Chen, Lanfang Li
Summary: Traditional Chinese medicine has therapeutic effects on atherosclerosis, with pharmacological roles involving endothelial function, cell proliferation and migration, platelet aggregation, and more. However, some traditional Chinese medicines may have toxic effects, requiring further research on their clinical safety and efficacy.
PHYTOTHERAPY RESEARCH
(2022)
Article
Integrative & Complementary Medicine
Jillian L. Capodice, Barbara M. Chubak
Summary: Traditional Chinese Medicine (TCM) is a comprehensive medical system that has been developed over thousands of years and is utilized in the treatment of COVID-19. This paper highlights the use of TCM in treating COVID-19, discussing concepts and challenges of integrating TCM into medical settings.
Review
Medicine, Research & Experimental
Qi Jin, Tongtong Liu, Fang Ma, Liping Yang, Huimin Mao, Yuyang Wang, Ping Li, Liang Peng, Yongli Zhan
Summary: Sirtuins are a family of protein deacetylases that regulate signaling pathways and are involved in kidney disease processes. Traditional Chinese medicine has made advancements in the treatment of kidney diseases, and this review explores the relationship between Sirtuins and common kidney diseases, as well as the role of traditional Chinese medicine in regulating these diseases.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Integrative & Complementary Medicine
Changning Liu, Lijuan Zhang, Ying Li, Mingxiang Li, Huan Han, Kangfeng Wang
Summary: The study compared the efficacy and safety of Chinese patent medicine with western medicine for the treatment of Alzheimer's disease using Network Meta-analysis. After analyzing 47 studies involving 11 Chinese patent medicines, the results showed that Chinese patent medicine intervention was more effective in improving patient condition and did not significantly increase the risk of adverse reactions. Chinese patent medicine combined with western medicine had statistically significant differences in various assessments compared to western medicine alone and Chinese patent medicine alone. More high-quality studies are needed for further verification.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2023)
Article
Integrative & Complementary Medicine
Tung Yan Lo, Anthony Siu Lung Chan, Suet Ting Cheung, Lisa Ying Yung, Manton Man Hon Leung, Yung Hou Wong
Summary: Yang Xin Tang (YXT), a traditional Chinese herbal preparation, has been reported to improve cognitive function and memory in patients with dementia. This study found that YXT and its major herbal components can regulate gene transcription and molecular targets related to Alzheimer's disease (AD). The neuroprotective and neurogenic actions of YXT suggest its potential as an alternative medicine for treating AD.
Review
Integrative & Complementary Medicine
Sun Ying-xin, Jiang Xi-juan, Lu Bin, Gao Qing, Chen Ye-fei, Wu Dan-bin, Zeng Wen-yun, Yang Lin, Li Hu-hu, Yu Bin
Summary: This review examines the role of gut microbiota in the pathogenesis of Alzheimer's disease, as well as the potential therapeutic effects of traditional Chinese medicine in modulating the gut microbiota to improve cognitive impairment in AD patients.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2022)
Review
Pharmacology & Pharmacy
Qiongyao He, Hui Dong, Minmin Gong, Yujin Guo, Qingsong Xia, Jing Gong, Fuer Lu
Summary: Graves' disease is an autoimmune disease characterized by goiter and hyperthyroidism, with some patients also developing eye proptosis. Traditional treatment options have remained largely unchanged for the past 70 years and often result in high recurrence rates or lifelong hypothyroidism. New therapeutic ideas, including biologics, small molecule peptides, and immunomodulators, as well as the effective components of traditional Chinese medicine, have opened up new possibilities for treating Graves' disease.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Medicine, Research & Experimental
Lina Ma, Xuefan Jiang, Qiaoyi Huang, Wenxuan Chen, Huiqin Zhang, Hui Pei, Yu Cao, Huichan Wang, Hao Li
Summary: Alzheimer's disease is a neurodegenerative disorder characterized by cognitive decline and the formation of amyloid beta plaques and neurofibrillary tangles. Gut microbiota, a complex community of microorganisms in the gastrointestinal system, can impact cognitive function through the gut-brain axis. Imbalance in gut microbiota can lead to immune dysregulation and inflammation, potentially contributing to the onset and progression of Alzheimer's disease. Traditional Chinese medicine shows promise in treating Alzheimer's disease by regulating gut microbiota. This review provides insights and strategies for future Alzheimer's disease research and treatment.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Pharmacology & Pharmacy
Baoyue Zhang, Jun Zhao, Zhe Wang, Pengfei Guo, Ailin Liu, Guanhua Du
Summary: AD is a neurodegenerative disease with no cure currently available. A multi-target approach using Chinese herbal compounds was used to predict and validate potential anti-AD drugs, leading to the discovery of 12 compounds with promising activity against AD.
FRONTIERS IN PHARMACOLOGY
(2021)
