Common gamma chain (γc) cytokines differentially potentiate TNFR family signaling in antigen-activated CD8+ T cells

Combined Stimulation of IL-2 and 4-1BB Receptors Augments the Antitumor Activity of E7 DNA Vaccines by Increasing Ag-Specific CTL Responses

(2014) Ha Kim et al.   PLoS One

Agonist Antibodies to TNFR Molecules That Costimulate T and NK Cells

(2013) I. Melero et al.   CLINICAL CANCER RESEARCH

Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy

(2013) Wei Liao et al.   IMMUNITY

IL-21 promotes the expansion of CD27+CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells

(2013) Saskia JAM Santegoets et al.   Journal of Translational Medicine

Dynamic regulatory network controlling TH17 cell differentiation

(2013) Nir Yosef et al.   NATURE

Effects of Recombinant Human Interleukin 7 on T-Cell Recovery and Thymic Output in HIV-Infected Patients Receiving Antiretroviral Therapy: Results of a Phase I/IIa Randomized, Placebo-Controlled, Multicenter Study

(2012) Y. Lévy et al.   CLINICAL INFECTIOUS DISEASES

GATA-3 Regulates the Homeostasis and Activation of CD8+ T Cells

(2012) T.-S. Tai et al.   JOURNAL OF IMMUNOLOGY

IL-15-Dependent Upregulation of GITR on CD8 Memory Phenotype T Cells in the Bone Marrow Relative to Spleen and Lymph Node Suggests the Bone Marrow as a Site of Superior Bioavailability of IL-15

(2012) L. M. Snell et al.   JOURNAL OF IMMUNOLOGY

Dual Anti-OX40/IL-2 Therapy Augments Tumor Immunotherapy via IL-2R-Mediated Regulation of OX40 Expression

(2012) William L. Redmond et al.   PLoS One

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

(2011) T. A. Waldmann et al.   BLOOD

IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation

(2011) Wei Liao et al.   CURRENT OPINION IN IMMUNOLOGY

Role of Common-Gamma Chain Cytokines in NK Cell Development and Function: Perspectives for Immunotherapy

(2011) Raffaella Meazza et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Rapid and Transient Activation of    T Cells to IFN-  Production, NK Cell-Like Killing, and Antigen Processing during Acute Virus Infection

(2011) F. N. Toka et al.   JOURNAL OF IMMUNOLOGY

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Autocrine IL-2 is required for secondary population expansion of CD8+ memory T cells

(2011) Sonia Feau et al.   NATURE IMMUNOLOGY

Common Gamma Chain Cytokines Promote Rapid In Vitro Expansion of Allo-Specific Human CD8+ Suppressor T Cells

(2011) Yuming Yu et al.   PLoS One

Monocyte trafficking in acute and chronic inflammation

(2011) Molly A. Ingersoll et al.   TRENDS IN IMMUNOLOGY

Cytokines and the inception of CD8 T cell responses

(2011) Maureen A. Cox et al.   TRENDS IN IMMUNOLOGY

Immobilized MHC class I chain-related protein A synergizes with IL-15 and soluble 4-1BB ligand to expand NK cells with high cytotoxicity ex vivo

(2010) Weijuan Gong et al.   Cellular & Molecular Immunology

IL-15 induces CD8+ T cells to acquire functional NK receptors capable of modulating cytotoxicity and cytokine secretion

(2010) Margareta P. Correia et al.   IMMUNOBIOLOGY

IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

(2008) C. S. Hinrichs et al.   BLOOD

High‐dose interleukin‐2 for the treatment of metastatic renal cell carcinoma

(2008) Jacob A. Klapper et al.   CANCER

IL-21 induces in vivo immune activation of NK cells and CD8+ T cells in patients with metastatic melanoma and renal cell carcinoma

(2008) Klaus Stensgaard Frederiksen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Distinct regulation of effector and memory T-cell differentiation

(2008) Axel Kallies   IMMUNOLOGY AND CELL BIOLOGY