PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo

The Endocannabinoid Metabolite Prostaglandin E2(PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2and EP Receptors

(2017) Caroline Turcotte et al.   JOURNAL OF IMMUNOLOGY

Visualizing the function and fate of neutrophils in sterile injury and repair

(2017) Jing Wang et al.   SCIENCE

The lipoxygenase pathway in zebrafish. Expression and characterization of zebrafish ALOX5 and comparison with its human ortholog

(2016) Susan Adel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Glucocorticoid-Induced Attenuation of the Inflammatory Response in Zebrafish

(2016) Antonia Chatzopoulou et al.   ENDOCRINOLOGY

Reverse Migration of Neutrophils: Where, When, How, and Why?

(2016) Sussan Nourshargh et al.   TRENDS IN IMMUNOLOGY

The Anti-Inflammatory Effects of Prostaglandins

(2016) Jose U. Scher et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Dose-dependent effects of prostaglandin E2 in macrophage adhesion and migration

(2015) Inés C. Osma-Garcia et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Defining the phenotype of neutrophils following reverse migration in zebrafish

(2015) Felix Ellett et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Redox and Src family kinase signaling control leukocyte wound attraction and neutrophil reverse migration

(2014) Sebastien Tauzin et al.   JOURNAL OF CELL BIOLOGY

Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport

(2014) Daqing Jin et al.   NATURE CELL BIOLOGY

A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

(2014) A. L. Robertson et al.   Science Translational Medicine

The role of prostaglandins in allergic lung inflammation and asthma

(2014) Dru Claar et al.   Expert Review of Respiratory Medicine

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular and pharmacological characterization of zebrafish ‘relaxant’ prostanoid receptors

(2013) Kyoshiro Tsuge et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular and pharmacological characterization of zebrafish ‘contractile’ and ‘inhibitory’ prostanoid receptors

(2013) Ryo Iwasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Zebrafish as a Novel Vertebrate Model To Dissect Enterococcal Pathogenesis

(2013) Tomasz K. Prajsnar et al.   INFECTION AND IMMUNITY

Retrotaxis of human neutrophils during mechanical confinement inside microfluidic channels

(2013) Bashar Hamza et al.   Integrative Biology

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipoxin A4 Regulates Natural Killer Cell and Type 2 Innate Lymphoid Cell Activation in Asthma

(2013) C. Barnig et al.   Science Translational Medicine

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Live Imaging of Tumor Initiation in Zebrafish Larvae Reveals a Trophic Role for Leukocyte-Derived PGE2

(2012) Yi Feng et al.   CURRENT BIOLOGY

Live Imaging Reveals Differing Roles of Macrophages and Neutrophils during Zebrafish Tail Fin Regeneration

(2012) Li Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multifaceted roles of PGE2 in inflammation and cancer

(2012) Masako Nakanishi et al.   Seminars in Immunopathology

Activation of hypoxia-inducible factor-1  (Hif-1 ) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

(2011) P. M. Elks et al.   BLOOD

COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps

(2011) Y. Nakanishi et al.   CARCINOGENESIS

Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

(2011) Abigail Woodfin et al.   NATURE IMMUNOLOGY

Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development

(2011) U. Haas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Neutrophil Apoptosis in the Resolution of Inflammation

(2011) Driss El Kebir et al.   TheScientificWorldJOURNAL

Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish

(2011) Caroline Gray et al.   THROMBOSIS AND HAEMOSTASIS

Neutrophil clearance: when the party is over, clean-up begins

(2011) Donna L. Bratton et al.   TRENDS IN IMMUNOLOGY

Interleukin-13 Signaling and Its Role in Asthma

(2011) Efren L. Rael et al.   World Allergy Organization Journal

Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation

(2010) Charles N. Serhan   AMERICAN JOURNAL OF PATHOLOGY

The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

(2010) David M. Tobin et al.   CELL

Neutrophil Apoptosis: Relevance to the Innate Immune Response and Inflammatory Disease

(2010) Sarah Fox et al.   Journal of Innate Immunity

Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice

(2010) Savita Khanna et al.   PLoS One

A Transgenic Mouse Model of Inducible Macrophage Depletion

(2009) Itamar Goren et al.   AMERICAN JOURNAL OF PATHOLOGY

Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish

(2009) Catherine A. Loynes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-α

(2008) Sylwia Michlewska et al.   FASEB JOURNAL