Article
Cell Biology
Yu Shi, Xudong Mao, Mingcheng Cai, Shenqiang Hu, Xiulan Lai, Shiyi Chen, Xianbo Jia, Jie Wang, Songjia Lai
Summary: miR-194-5p negatively regulates the proliferation and differentiation of rabbit skeletal muscle satellite cells by targeting Mef2c.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Shuailong Zheng, Li Li, Helin Zhou, Xujia Zhang, Xiaoli Xu, Dinghui Dai, Siyuan Zhan, Jiaxue Cao, Jiazhong Guo, Tao Zhong, Linjie Wang, Hongping Zhang
Summary: This study identifies a novel circular RNA, circTCF4, which is specifically expressed during the development of the longest dorsal muscle in goats and is enriched in muscle tissue. The study demonstrates that circTCF4 inhibits the proliferation and differentiation of MuSCs and affects muscle differentiation by influencing multiple signaling pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Xiong Wang, Fan Liu, Qin An, Wenli Wang, Zhimei Cheng, Yunping Dai, Qingyong Meng, Yali Zhang
Summary: Lactoferrin (Ltf) plays a protective role in skeletal muscle by promoting the proliferation of satellite cells (SCs) and skeletal muscle regeneration. It holds promise as a novel therapeutic agent for skeletal muscle injuries.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Genetics & Heredity
Yun Zhu, Peng Li, Xingang Dan, Xiaolong Kang, Yun Ma, Yuangang Shi
Summary: miR-377 regulates the proliferation and differentiation of bovine skeletal muscle satellite cells through targeting FHL2 and attenuating the Wnt/beta-catenin signaling pathway.
Article
Physiology
Kent M. Reed, Kristelle M. Mendoza, Gale M. Strasburg, Sandra G. Velleman
Summary: Thermal stress has a significant impact on muscle development and gene expression in turkey satellite cells. Commercially selected birds show greater changes in calcium signaling and gene transcription in response to heat stress compared to slower-growing research lines.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Chengchuang Song, Xue Fang, Zhaoxin Yang, Qi Wang, Fantong Meng, Yaqi Chen, Junhao Chen, Bei Zhao, Yanhong Wang, Xingtang Fang, Lihong Gu, Chunlei Zhang
Summary: Our study shows that miR-152 inhibits proliferation of bovine myoblasts by targeting KLF6, which has certain effects on the development of bovine skeletal muscles.
Article
Biochemistry & Molecular Biology
Cecilia Romagnoli, Roberto Zonefrati, Elena Lucattelli, Marco Innocenti, Roberto Civinini, Teresa Iantomasi, Maria Luisa Brandi
Summary: This study evaluated the effects of PTH on the proliferation and differentiation of skeletal muscle satellite cells isolated from human biopsies. Results showed no significant changes in cAMP and proliferation in the isolated cells treated with PTH, but differentiated myotubes treated with PTH exhibited increased cAMP, expression of myogenic differentiation genes, and MHC protein. This study provides new insights into the effects of PTH on human skeletal muscle cells and opens new avenues for research in muscle pathophysiology.
Article
Biochemistry & Molecular Biology
Jiyuan Shen, Jiqing Wang, Huimin Zhen, Yan Liu, Lu Li, Yuzhu Luo, Jiang Hu, Xiu Liu, Shaobin Li, Zhiyun Hao, Mingna Li, Zhidong Zhao
Summary: The study revealed that miR-381 promoted myogenic differentiation of caprine skeletal muscle satellite cells and regulated cell activities by targeting JAG2 and PTEN, providing important clues for a better understanding of the molecular mechanisms underlying muscle growth.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Di Sun, Jiaqi An, Zixu Cui, Jiao Li, Ziwei You, Chang Lu, Yang Yang, Pengfei Gao, Xiaohong Guo, Bugao Li, Chunbo Cai, Guoqing Cao
Summary: This study identifies a novel circRNA, circCSDE1, that is highly expressed in skeletal muscle. Functional studies show that circCSDE1 promotes proliferation and inhibits myoblast differentiation, while miR-21-3p has opposite effects. Dual-luciferase reporter assay confirms that circCSDE1 targets miR-21-3p directly.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Huimin Zhen, Jiyuan Shen, Jiqing Wang, Yuzhu Luo, Jiang Hu, Xiu Liu, Shaobin Li, Zhiyun Hao, Mingna Li, Bingang Shi, Yuanhua Gu
Summary: circ_003628 is a highly expressed circular RNA in goat skeletal muscle tissue, and it affects muscle growth and development by promoting the proliferation and differentiation of goat skeletal muscle satellite cells.
Article
Biotechnology & Applied Microbiology
Rebecca Wuest, Lisanne Terrie, Thomas Muentefering, Tobias Ruck, Lieven Thorrez
Summary: Vascularization is a challenge in skeletal muscle tissue engineering. This study introduces a novel method for co-isolation of human skeletal muscle microvascular endothelial cells and satellite cell-derived myoblasts, enabling further studies on cell communication and the engineering of physiologically relevant functional tissue.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Health Care Sciences & Services
Karyn G. Robinson, Adam G. Marsh, Stephanie K. Lee, Jonathan Hicks, Brigette Romero, Mona Batish, Erin L. Crowgey, M. Wade Shrader, Robert E. Akins
Summary: This study examined the DNA methylation differences in myoblasts and myotubes derived from satellite cells in patients with spastic cerebral palsy (CP). The results showed significant DNA methylation differences in these cells, suggesting potential new targets for studying the mechanisms contributing to muscle dysregulation in spastic CP.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Cell & Tissue Engineering
Congshan Sun, Suraj Kannan, In Young Choi, HoTae Lim, Hao Zhang, Grace S. Chen, Nancy Zhang, Seong-Hyun Park, Carlo Serra, Shama R. Iyer, Thomas E. Lloyd, Richard M. Lovering, Su Bin Lim, Peter Andersen, Kathryn R. Wagner, Gabsang Lee, Chulan Kwon
Summary: Human pluripotent stem cell (hPSC)-derived myogenic progenitor cell (MPC) transplantation can contribute to muscle fiber regeneration in mice, providing a proof of principle for future hPSC-based cell therapy for muscle disorders.
Article
Agriculture, Dairy & Animal Science
Shan Wang, Xiukai Cao, Ling Ge, Yifei Gu, Xiaoyang Lv, Tesfaye Getachew, Joram M. Mwacharo, Aynalem Haile, Wei Sun
Summary: This study conducted functional verification of miRNA in Hu sheep skeletal muscle cells and found that miR-22-3p plays a role in the proliferation and differentiation of Hu sheep skeletal muscle cells by targeting IGFBP3.
Article
Veterinary Sciences
Jie Song, Linlin Hao, Xiangfang Zeng, Rui Yang, Shiyan Qiao, Chunli Wang, Hao Yu, Siyao Wang, Yingying Jiao, Hongyao Jia, Songcai Liu, Ying Zhang
Summary: This study aimed to investigate the effects of novel miRNA Y-56 on porcine skeletal muscle satellite cells (PSCs) and found that Y-56 inhibited cell proliferation and cell cycle by targeting the IGF-1R-mediated AKT and ERK pathways.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Cell Biology
WeiWei Zhang, HuiLi Tong, ZiHeng Zhang, ShuLi Shao, Dan Liu, ShuFeng Li, YunQin Yan
JOURNAL OF CELLULAR PHYSIOLOGY
(2018)
Article
Cell Biology
Jiahui Xu, Dan Liu, Hongyan Yin, Huili Tong, Shufeng Li, Yunqin Yan
CELL AND TISSUE RESEARCH
(2018)
Article
Cell Biology
Chang Liu, Huili Tong, Shufeng Li, Yunqin Yan
CELL BIOLOGY INTERNATIONAL
(2018)
Article
Genetics & Heredity
HuiLi Tong, RunYing Jiang, TingTing Liu, Yao Wei, ShuFeng Li, YunQin Yan
Article
Cell Biology
Shuang Zhou, Shuang Li, Weiwei Zhang, Huili Tong, Shufeng Li, Yunqin Yan
JOURNAL OF CELLULAR PHYSIOLOGY
(2019)
Article
Multidisciplinary Sciences
Hui Li Tong, Run Ying Jiang, Wei Wei Zhang, Yun Qin Yan
SCIENTIFIC REPORTS
(2017)
Article
Cell Biology
Yao Ge, Shuang Li, Xiao-Yang Hu, Hui-Li Tong, Shu-Feng Li, Yun-Qin Yan
JOURNAL OF CELLULAR PHYSIOLOGY
(2019)
Article
Cell Biology
Dan Liu, Shuang Li, Yafeng Cui, Huili Tong, Shufeng Li, Yunqin Yan
JOURNAL OF CELLULAR PHYSIOLOGY
(2019)
Article
Cell Biology
Yuying Fu, Shuang Li, Huili Tong, Shufeng Li, Yunqin Yan
CELL BIOLOGY INTERNATIONAL
(2019)
Article
Cell Biology
Shuang Li, Yuying Fu, Yusheng Pang, Huili Tong, Shufeng Li, Yunqin Yan
JOURNAL OF CELLULAR PHYSIOLOGY
(2019)
Article
Physiology
Shuang Li, Dan Liu, Yuying Fu, Chunyu Zhang, Huili Tong, Shufeng Li, Yunqin Yan
FRONTIERS IN PHYSIOLOGY
(2019)
Article
Cell Biology
Shuang Li, Zhiqi Wang, Huili Tong, Shufeng Li, Yunqin Yan
JOURNAL OF CELLULAR PHYSIOLOGY
(2020)
Article
Cell Biology
Chunyu Zhang, Yuhan Zhang, Wenyu Zhang, Huili Tong, Shufeng Li, Yunqin Yan
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2020)
Article
Biochemistry & Molecular Biology
Dan Liu, Jia-Hui Xu, Hui-Li Tong, Shu-Feng Li, Yun-Qin Yan
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2017)
Article
Biochemistry & Molecular Biology
Yue Zhu, Hui-Li Tong, Shu-Feng Li, Yun-Qin Yan
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2017)
Article
Biochemistry & Molecular Biology
Soojung Hahn, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim
Summary: This study utilized three-dimensional intestinal organoids to investigate the effects of metformin on inflammatory bowel disease (IBD) and found that metformin can enhance intestinal barrier function and reduce levels of inflammatory cytokines.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
V. V. Sudarev, M. S. Gette, S. V. Bazhenov, O. M. Tilinova, E. V. Zinovev, I. V. Manukhov, A. I. Kuklin, Yu. L. Ryzhykau, A. V. Vlasov
Summary: This study investigated the self-assembly processes of ferritin-based protein complexes and obtained structurally characterized oligomeric states. These results provide new potential and opportunities for the application of ferritin in various fields.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Yalda Sabaghi, Farnaz Pourfarzad, Leila Zolghadr, Azita Bahrami, Tahereh Shojazadeh, Alireza Farasat, Nematollah Gheibi
Summary: p-Coumaric acid (p-CA) is a plant compound with anti-cancer activities. This study designed a nano-liposomal carrier containing p-CA to enhance its effectiveness against melanoma cells. The findings showed that the liposomal form of p-CA had a greater impact on the cells. Kinetic modeling indicated that the best fitting model was zero-order.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
M. D. Nazmul Hasan, Md Mahfuzur Rahman, Al Asmaul Husna, Nobuhiro Nozaki, Osamu Yamato, Naoki Miura
Summary: This study investigated the expression of ncRNAs other than miRNAs in different histologic subtypes of canine mammary gland tumors (MGT). Three aberrantly expressed ncRNAs were identified as potential biomarkers for differentiating MGT subtypes. YRNA and tRFs expression levels were found to be decreased in metastatic compared to primary MGT cell lines.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Seine A. Shintani
Summary: In this study, the researchers used signal analysis to study the instantaneous amplitude and phase of sarcomeric oscillations in skeletal muscle. They identified two types of oscillations, sarcomeric oscillations and sarcosynced oscillations, and visualized their behavior during propagating waves. The researchers discovered the presence of sarcomeric defect holes and sarcomeric collision holes, which are important indicators for understanding the oscillation properties of sarcomeres. This finding has important implications for improving our understanding of muscle function and its regulatory mechanisms.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Shuanglin Zhang, Yuzhong Jia, Guolan Ma, Yanyan Yang, Zhenzhen Cao, Antao Luo, Zefu Zhang, Shihan Li, Jie Wen, Hanfeng Liu, Jihua Ma
Summary: Bupleurum is an antiarrhythmic agent that may exert its effects by inhibiting L-type calcium channels.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Tomotaka Ohkubo, Yasuhiko Matsumoto, Hiroaki Sasaki, Kaoru Kinoshita, Yuki Ogasawara, Takashi Sugita
Summary: This study found that Citrobacter koseri inhibits the growth of Staphylococcus epidermidis, disrupting the balance between S. epidermidis and Staphylococcus aureus, and exacerbating inflammation in atopic dermatitis.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Toshifumi Asano, Philipp Sasse, Takao Nakata
Summary: A Cre recombination-based fluorescent reporter system was developed to monitor cell-cell fusion. The system successfully detected the formation of multinuclear myotubes and placental syncytiotrophoblast. This tool could facilitate the study of cell-to-cell fusion.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Ke Shi, Yunlong Shan, Xiao Sun, Kuida Chen, Qiong Luo, Qiang Xu
Summary: This study found that low expression of TP53INP2 is associated with poor survival in colorectal cancer (CRC) patients. As the malignancy of CRC progresses, TP53INP2 expression gradually decreases. Knockdown of TP53INP2 promotes CRC cell proliferation and tumor growth. Mechanistically, TP53INP2 deficiency decreases phosphorylation of beta-catenin, leading to increased accumulation and enhanced nuclear translocation and transcriptional activity. Additionally, TP53INP2 sequesters TIM50, inhibiting its activation of beta-catenin. In conclusion, downregulation of TP53INP2 promotes CRC progression by activating beta-catenin.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Martina Rossi, Fabio Tomaselli, Alejandro Hochkoeppler
Summary: Oligomeric enzymes are known for their higher catalytic rates compared to monomeric enzymes, but the extent of additivity in their activity is still not well understood. This study used tetrameric rabbit lactate dehydrogenase as a model to examine the kinetics of its catalytic action. Surprisingly, when the concentration of the limiting reactant exceeded that of a single subunit, there was a significant slowdown in the enzyme's conformational rearrangements.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Amin Sahraei, Mohammad Javad Shamsoddini, Fakhrossadat Mohammadi, Leila Hassani
Summary: This study explored the inhibitory effects of gallium curcumin, indium curcumin, and vanadyl curcumin on the amyloid fibrillation of hen egg white lysozyme, as well as the binding interactions of these metal complexes with the enzyme. The results showed that indium curcumin and vanadyl curcumin exhibited higher binding affinities and stronger inhibitory effects on amyloid fibrillation compared to gallium curcumin.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Takahiro Sasaki, Yoshiki Kuse, Shinsuke Nakamura, Masamitsu Shimazawa
Summary: PGRN deficiency plays a significant role in cardiac remodeling and arrhythmias post-myocardial infarction (MI), potentially by promoting metabolic abnormalities in macrophages.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Hongwei Zhao, Yiqiang Li, Yibo Zhang, Chi Zhang
Summary: Electrical brain stimulation technology is commonly used to treat brain neurological disorders, but it can cause side effects. This study investigated the impact of electric fields on nerve fibers and revealed the possible origin of side effects. The findings provide guidance for selecting electrical parameters in clinical stimulation therapy.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Julia S. Scott, Lake-Ee Quek, Andrew J. Hoy, Johannes V. Swinnen, Zeyad D. Nassar, Lisa M. Butler
Summary: The fatty acid elongation enzyme ELOVL5 plays a critical role in promoting metastasis in prostate cancer. Knocking down ELOVL5 leads to the accumulation of malonyl-CoA, which inhibits fatty acid oxidation in mitochondria. This study highlights the importance of fatty acid elongation in regulating cell viability and provides a potential target for prostate cancer treatment.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Zan Zhou, Wen-jun Jiang, Li Li, Jun-qiang Si
Summary: This study investigates the effect of noise exposure on cognitive function in mice and explores the underlying molecular mechanisms. The findings suggest that noise exposure leads to increased inflammation, increased phosphorylation of Tau protein, and decreased levels of postsynaptic density protein, resulting in cognitive impairment.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2024)