Nitric Oxide Deficiency in Pulmonary Hypertension: Pathobiology and Implications for Therapy

A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of Oral Sildenafil Citrate in Treatment-Naive Children With Pulmonary Arterial Hypertension

(2011) Robyn J. Barst et al.   CIRCULATION

Riociguat for the treatment of pulmonary hypertension

(2011) Ralph T Schermuly et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Bone Morphogenetic Protein Receptor II Is a Novel Mediator of Endothelial Nitric-oxide Synthase Activation

(2011) Archana Gangopahyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Response to Inhaled Nitric Oxide Predicts Survival in Patients With Pulmonary Hypertension

(2011) Richard A. Krasuski et al.   JOURNAL OF CARDIAC FAILURE

Mechanisms of disease: pulmonary arterial hypertension

(2011) Ralph T. Schermuly et al.   Nature Reviews Cardiology

Pulmonary hypertension, nitric oxide and nitric oxide-releasing compounds

(2011) Guy Hagan et al.   Expert Review of Respiratory Medicine

l-Arginine restores endothelial nitric oxide synthase-coupled activity and attenuates monocrotaline-induced pulmonary artery hypertension in rats

(2010) Zhi-Jun Ou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exhaled Nitric Oxide in Pulmonary Diseases

(2010) Peter J. Barnes et al.   CHEST

Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study

(2010) H. A. Ghofrani et al.   EUROPEAN RESPIRATORY JOURNAL

Safety of sapropterin dihydrochloride (6r–bh4) in patients with pulmonary hypertension

(2010) Ivan M. Robbins et al.   EXPERIMENTAL LUNG RESEARCH

Inhaled nitric oxide for prevention of bronchopulmonary dysplasia in premature babies (EUNO): a randomised controlled trial

(2010) Jean-Christophe Mercier et al.   LANCET

Low-dose sodium nitrite vasodilates hypoxic human pulmonary vasculature by a means that is not dependent on a simultaneous elevation in plasma nitrite

(2009) Thomas E. Ingram et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

l-Arginine promotes angiogenesis in the chronically hypoxic lung: a novel mechanism ameliorating pulmonary hypertension

(2009) K. Howell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

l-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets

(2009) Madhumita Ananthakrishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pulmonary Vascular Reactivity and Prognosis in Patients With Chronic Thromboembolic Pulmonary Hypertension

(2009) Nika Skoro-Sajer et al.   CIRCULATION

Tadalafil Therapy for Pulmonary Arterial Hypertension

(2009) Nazzareno Galiè et al.   CIRCULATION

Development and Pathology of Pulmonary Hypertension

(2009) Rubin M. Tuder et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Updated Evidence-Based Treatment Algorithm in Pulmonary Arterial Hypertension

(2009) Robyn J. Barst et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pulmonary vasodilator testing and use of calcium channel blockers in pulmonary arterial hypertension

(2009) Adriano R. Tonelli et al.   RESPIRATORY MEDICINE

Bringing down the ROS: a new therapeutic approach for PPHN

(2008) Amy L. Firth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension

(2008) Kathryn N. Farrow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The functional nitrite reductase activity of the heme-globins

(2008) M. T. Gladwin et al.   BLOOD

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension

(2008) R. T. Schermuly et al.   EUROPEAN RESPIRATORY JOURNAL

Long-term Inhaled Nitric Oxide Plus Phosphodiesterase 5 Inhibitors for Severe Pulmonary Hypertension

(2008) Gregorio Miguel Pérez-Peñate et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

(2008) Jon O. Lundberg et al.   NATURE REVIEWS DRUG DISCOVERY