Nuclear Receptors and Endocrine Disruptors in Fetal and Neonatal Testes: A Gapped Landscape

Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men

(2015) Laura O’Hara et al.   FASEB JOURNAL

A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound

(2015) Soria Eladak et al.   FERTILITY AND STERILITY

Estrogen-related receptor γ is an in vivo receptor of bisphenol A

(2014) Marie Tohmé et al.   FASEB JOURNAL

Levels of liver X receptors in testicular biopsies of patients with azoospermia

(2014) Christine Rondanino et al.   FERTILITY AND STERILITY

Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells

(2014) K. R. Kilcoyne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors

(2014) René Habert et al.   REPRODUCTION

The regulation of spermatogenesis by androgens

(2014) Lee B. Smith et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Is bisphenol S a safe substitute for bisphenol A in terms of metabolic function? An in vitro study

(2014) Cécile Héliès-Toussaint et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Insulin-Like Factor 3 and the HPG Axis in the Male

(2014) Richard Ivell et al.   Frontiers in Endocrinology

Bisphenol A: An endocrine and metabolic disruptor

(2013) Patrick Fenichel et al.   ANNALES D ENDOCRINOLOGIE

Liver X receptors interfere with the deleterious effect of diethylstilbestrol on testicular physiology

(2013) Abdelkader Oumeddour et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Non-Monotonic Dose Responses in Studies of Endocrine Disrupting Chemicals: Bisphenol a as a Case Study

(2013) Laura N. Vandenberg   Dose-Response

Excess Androgens in Utero Alters Fetal Testis Development

(2013) Fiona Connolly et al.   ENDOCRINOLOGY

The association between some endocrine disruptors and hypospadias in biological samples

(2013) Haemin Choi et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING

Activation of PPAR α and PPAR β/δ regulates Sertoli cell metabolism

(2013) M. Regueira et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Diethylstilboestrol Exposure Does Not Reduce Testosterone Production in Human Fetal Testis Xenografts

(2013) Rod T. Mitchell et al.   PLoS One

Evaluation of a Screening System for Obesogenic Compounds: Screening of Endocrine Disrupting Compounds and Evaluation of the PPAR Dependency of the Effect

(2013) Anna Pereira-Fernandes et al.   PLoS One

Bisphenol A and human health: A review of the literature

(2013) Johanna R. Rochester   REPRODUCTIVE TOXICOLOGY

Differential Response to Abiraterone Acetate and Di-n-butyl Phthalate in an Androgen-Sensitive Human Fetal Testis Xenograft Bioassay

(2013) Daniel J. Spade et al.   TOXICOLOGICAL SCIENCES

In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors

(2013) José-Manuel Molina-Molina et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses

(2012) Laura N. Vandenberg et al.   ENDOCRINE REVIEWS

Human Fetal Testis Xenografts Are Resistant to Phthalate-Induced Endocrine Disruption

(2012) Nicholas E Heger et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Unconjugated bisphenol A cord blood levels in boys with descended or undescended testes

(2012) P. Fenichel et al.   HUMAN REPRODUCTION

Do Phthalates Affect Steroidogenesis by the Human Fetal Testis? Exposure of Human Fetal Testis Xenografts to Di-n-Butyl Phthalate

(2012) R. T. Mitchell et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cholesterol and male fertility: What about orphans and adopted?

(2012) Salwan Maqdasy et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

GPR30, the Non-Classical Membrane G Protein Related Estrogen Receptor, Is Overexpressed in Human Seminoma and Promotes Seminoma Cell Proliferation

(2012) Nicolas Chevalier et al.   PLoS One

Cellular and Molecular Effect of MEHP Involving LXRα in Human Fetal Testis and Ovary

(2012) Vincent Muczynski et al.   PLoS One

Differential Effects of Bisphenol A and Diethylstilbestrol on Human, Rat and Mouse Fetal Leydig Cell Function

(2012) Thierry N’Tumba-Byn et al.   PLoS One

Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiol

(2012) Gary R Klinefelter et al.   REPRODUCTION

Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: In vitro and in vivo approaches

(2012) V. Muczynski et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Liver X receptors, lipids and their reproductive secrets in the male

(2011) Fatim-Zorah El-Hajjaji et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

In utero exposure to bisphenol-A and anogenital distance of male offspring

(2011) Maohua Miao et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system

(2011) Jessica LaRocca et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Peroxisome Proliferator-Activated Receptor γ Is a Target for Halogenated Analogs of Bisphenol A

(2011) Anne Riu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Low doses of bisphenol a induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver

(2011) Alice Marmugi et al.   HEPATOLOGY

Fetal exposure to bisphenol A affects the primordial follicle formation by inhibiting the meiotic progression of oocytes

(2011) Han-Qiong Zhang et al.   MOLECULAR BIOLOGY REPORTS

Testicular descent: INSL3, testosterone, genes and the intrauterine milieu

(2011) Katrine Bay et al.   Nature Reviews Urology

Genomic Biomarkers of Phthalate-Induced Male Reproductive Developmental Toxicity: A Targeted RT-PCR Array Approach for Defining Relative Potency

(2011) Bethany R. Hannas et al.   TOXICOLOGICAL SCIENCES

Characterization of Novel Ligands of ERα, Erβ, and PPARγ: The Case of Halogenated Bisphenol A and Their Conjugated Metabolites

(2011) Anne Riu et al.   TOXICOLOGICAL SCIENCES

Use of genomic data in risk assessment case study: II. Evaluation of the dibutyl phthalate toxicogenomic data set

(2011) Susan Y. Euling et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genital anomalies in boys and the environment

(2010) Katharina M. Main et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Viable skin efficiently absorbs and metabolizes bisphenol A

(2010) Daniel Zalko et al.   CHEMOSPHERE

Adverse effects of endocrine disruptors on the foetal testis development: focus on the phthalates.

(2010) RenĂŠ Habert et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Minireview: Extranuclear Steroid Receptors: Roles in Modulation of Cell Functions

(2010) Ellis R. Levin   MOLECULAR ENDOCRINOLOGY

Aromatase, oestrogens and human male reproduction

(2010) S. Carreau et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Steroidogenesis in the Fetal Testis and Its Susceptibility to Disruption by Exogenous Compounds

(2009) Hayley M. Scott et al.   ENDOCRINE REVIEWS

In UteroExposure to Di-(2-Ethylhexyl) Phthalate Decreases Mineralocorticoid Receptor Expression in the Adult Testis

(2009) D. B. Martinez-Arguelles et al.   ENDOCRINOLOGY

Low Doses of Bisphenol A Promote Human Seminoma Cell Proliferation by Activating PKA and PKG via a Membrane G-Protein–Coupled Estrogen Receptor

(2009) Adil Bouskine et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Perinatal Exposure to Bisphenol A Alters Early Adipogenesis in the Rat

(2009) Emmanuel Somm et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Di (n-butyl) Phthalate Inhibits Testosterone Synthesis Through a Glucocorticoid-Mediated Pathway in Rats

(2009) Zhang Xiao-feng et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Lack of Androgen Receptor Expression in Sertoli Cells Accounts for the Absence of Anti-Mullerian Hormone Repression during Early Human Testis Development

(2009) Kahina Boukari et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice

(2009) David H. Volle et al.   JOURNAL OF CLINICAL INVESTIGATION

Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring

(2009) Smita Salian et al.   LIFE SCIENCES

Phthalates Impair Germ Cell Number in the Mouse Fetal Testis by an Androgen- and Estrogen-Independent Mechanism

(2009) Abdelali Lehraiki et al.   TOXICOLOGICAL SCIENCES

Association between prenatal exposure to phthalates and the health of newborns☆

(2008) P HUANG et al.   ENVIRONMENT INTERNATIONAL

Time- and Dose-Related Effects of Di-(2-ethylhexyl) Phthalate and Its Main Metabolites on the Function of the Rat Fetal Testis in Vitro

(2008) François Chauvigné et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Phthalates Impair Germ Cell Development in the Human Fetal Testis in Vitro without Change in Testosterone Production

(2008) Romain Lambrot et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

(2008) Richard M. Sharpe et al.   FERTILITY AND STERILITY

Exposure of the mouse perinatal testis to radiation leads to hypospermia at sexual maturity

(2008) A Forand et al.   REPRODUCTION

Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats

(2008) Julie Boberg et al.   TOXICOLOGY

Direct Evidence Revealing Structural Elements Essential for the High Binding Ability of Bisphenol A to Human Estrogen-Related Receptor-γ

(2007) Hiroyuki Okada et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Peroxisome Proliferator-Activated Receptors as Mediators of Phthalate-Induced Effects in the Male and Female Reproductive Tract: Epidemiological and Experimental Evidence

(2007) Giuseppe Latini et al.   PPAR Research