Role of the Axonal Initial Segment in Psychiatric Disorders: Function, Dysfunction, and Intervention
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of the Axonal Initial Segment in Psychiatric Disorders: Function, Dysfunction, and Intervention
Authors
Keywords
-
Journal
Frontiers in Psychiatry
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-08-21
DOI
10.3389/fpsyt.2014.00109
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The NIMH Research Domain Criteria (RDoC) Project: Precision Medicine for Psychiatry
- (2014) Thomas R. Insel AMERICAN JOURNAL OF PSYCHIATRY
- Ankyrin-G Directly Binds to Kinesin-1 to Transport Voltage-Gated Na+ Channels into Axons
- (2014) Joshua Barry et al. DEVELOPMENTAL CELL
- Drug Design Targeting Protein–Protein Interactions (PPIs) Using Multiple Ligand Simultaneous Docking (MLSD) and Drug Repositioning: Discovery of Raloxifene and Bazedoxifene as Novel Inhibitors of IL-6/GP130 Interface
- (2014) Huameng Li et al. JOURNAL OF MEDICINAL CHEMISTRY
- Activity-Dependent and Activity-Independent Development of the Axon Initial Segment
- (2014) H. Kuba et al. JOURNAL OF NEUROSCIENCE
- Tailoring Peptidomimetics for Targeting Protein–Protein Interactions
- (2014) Omar N. Akram et al. MOLECULAR CANCER RESEARCH
- Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy
- (2014) M.K. Oliva et al. NEUROBIOLOGY OF DISEASE
- GABAB receptor trafficking and interacting proteins: Targets for the development of highly specific therapeutic strategies to treat neurological disorders?
- (2013) Dietmar Benke BIOCHEMICAL PHARMACOLOGY
- Toward the future of psychiatric diagnosis: the seven pillars of RDoC
- (2013) Bruce N Cuthbert et al. BMC Medicine
- Potential Mechanisms of Action of Lithium in Bipolar Disorder
- (2013) Gin S. Malhi et al. CNS DRUGS
- Divergent effects of the T1174SSCN1Amutation associated with seizures and hemiplegic migraine
- (2013) Sandrine Cestèle et al. EPILEPSIA
- SCN1Atesting for epilepsy: Application in clinical practice
- (2013) Shinichi Hirose et al. EPILEPSIA
- Whole genome sequencing identifiesSCN2Amutation in monozygotic twins with Ohtahara syndrome and unique neuropathologic findings
- (2013) Marlin Touma et al. EPILEPSIA
- Axon initial segment structural plasticity in animal models of genetic and acquired epilepsy
- (2013) Rosemary C. Harty et al. EPILEPSY RESEARCH
- The Fibroblast Growth Factor 14·Voltage-gated Sodium Channel Complex Is a New Target of Glycogen Synthase Kinase 3 (GSK3)
- (2013) Alexander S. Shavkunov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Latest developments in molecular docking: 2010-2011 in review
- (2013) Elizabeth Yuriev et al. JOURNAL OF MOLECULAR RECOGNITION
- NaV1.1 Channels in Axon Initial Segments of Bipolar Cells Augment Input to Magnocellular Visual Pathways in the Primate Retina
- (2013) T. Puthussery et al. JOURNAL OF NEUROSCIENCE
- FGF14 localization and organization of the axon initial segment
- (2013) Maolei Xiao et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Anti-neurofascin antibody in patients with combined central and peripheral demyelination
- (2013) N. Kawamura et al. NEUROLOGY
- Twenty-Five Years of Progress: The View from NIMH and NINDS
- (2013) Thomas R. Insel et al. NEURON
- Integrative Biological Analysis For Neuropsychopharmacology
- (2013) Mark R Emmett et al. NEUROPSYCHOPHARMACOLOGY
- Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology
- (2013) Mohammadreza Shariatgorji et al. NEUROPSYCHOPHARMACOLOGY
- Innovative solutions to novel drug development in mental health
- (2013) T.R. Insel et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Possible Role of the Glycogen Synthase Kinase-3 Signaling Pathway in Trimethyltin-Induced Hippocampal Neurodegeneration in Mice
- (2013) Juhwan Kim et al. PLoS One
- The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity
- (2013) Mark W. Logue et al. PSYCHONEUROENDOCRINOLOGY
- The NIH BRAIN Initiative
- (2013) T. R. Insel et al. SCIENCE
- Evidence for single nucleotide polymorphisms and their association with bipolar disorder
- (2013) Aleksandra Szczepankiewicz Neuropsychiatric Disease and Treatment
- Cerebrospinal fluid biomarkers for Alzheimer disease and subcortical axonal damage in 5,542 clinical samples
- (2013) Tobias Skillbäck et al. Alzheimers Research & Therapy
- FGF14 Regulates Presynaptic Ca2+ Channels and Synaptic Transmission
- (2013) Haidun Yan et al. Cell Reports
- Comprehensive Peptidomimetic Libraries Targeting Protein–Protein Interactions
- (2012) Landon R. Whitby et al. ACCOUNTS OF CHEMICAL RESEARCH
- ANK3as a risk gene for schizophrenia: New data in han Chinese and meta analysis
- (2012) Aihua Yuan et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Sequencing of the ANKYRIN 3 gene (ANK3) encoding ankyrin G in bipolar disorder reveals a non-conservative amino acid change in a short isoform of ankyrin G
- (2012) Alexandra Dedman et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- The science and practice of lithium therapy
- (2012) Gin S Malhi et al. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
- The ANK3 Bipolar Disorder Gene Regulates Psychiatric-Related Behaviors That Are Modulated by Lithium and Stress
- (2012) Melanie P. Leussis et al. BIOLOGICAL PSYCHIATRY
- Small-molecule modulators of 14-3-3 protein–protein interactions
- (2012) Christian Ottmann BIOORGANIC & MEDICINAL CHEMISTRY
- A Family with Spinocerebellar Ataxia Type 5 Found to Have a Novel Missense Mutation within a SPTBN2 Spectrin Repeat
- (2012) Ellen Cho et al. CEREBELLUM
- Neurofascin: A switch between neuronal plasticity and stability
- (2012) Martin Kriebel et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Mesial Temporal Sclerosis in a Cohort of Children With SCN1A Gene Mutation
- (2012) Katherine Van Poppel et al. JOURNAL OF CHILD NEUROLOGY
- A novel ARC gene polymorphism is associated with reduced risk of Alzheimer’s disease
- (2012) Sara Landgren et al. JOURNAL OF NEURAL TRANSMISSION
- Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice
- (2012) A C Santuccione et al. MOLECULAR PSYCHIATRY
- Structure-based prediction of protein–protein interactions on a genome-wide scale
- (2012) Qiangfeng Cliff Zhang et al. NATURE
- De novo mutations revealed by whole-exome sequencing are strongly associated with autism
- (2012) Stephan J. Sanders et al. NATURE
- Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
- (2012) Brian J. O’Roak et al. NATURE
- Alterations in the expression of PSA-NCAM and synaptic proteins in the dorsolateral prefrontal cortex of psychiatric disorder patients
- (2012) Javier Gilabert-Juan et al. NEUROSCIENCE LETTERS
- A Fine-Mapping Study of 7 Top Scoring Genes from a GWAS for Major Depressive Disorder
- (2012) Eva C. Verbeek et al. PLoS One
- Next-Generation Treatments for Mental Disorders
- (2012) T. R. Insel Science Translational Medicine
- Recessive Mutations in SPTBN2 Implicate β-III Spectrin in Both Cognitive and Motor Development
- (2012) Stefano Lise et al. PLoS Genetics
- Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase
- (2012) Norelle C. Wildburger et al. Frontiers in Molecular Neuroscience
- The NIMH-CATIE Schizophrenia Study: What Did We Learn?
- (2011) Jeffrey A. Lieberman et al. AMERICAN JOURNAL OF PSYCHIATRY
- Molecular and Genetic Evidence for Abnormalities in the Nodes of Ranvier in Schizophrenia
- (2011) Panos Roussos ARCHIVES OF GENERAL PSYCHIATRY
- A de novo 1.5 Mb microdeletion on chromosome 14q23.2-23.3 in a patient with autism and spherocytosis
- (2011) Anthony J. Griswold et al. Autism Research
- Is Ankyrin a genetic risk factor for psychiatric phenotypes?
- (2011) Alejandro Gella et al. BMC Psychiatry
- Nav1.1 dysfunction in genetic epilepsy with febrile seizures-plus or Dravet syndrome
- (2011) Linda Volkers et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Mechanistic involvement of the calpain-calpastatin system in Alzheimer neuropathology
- (2011) Makoto Higuchi et al. FASEB JOURNAL
- The Cell Adhesion Molecule Neurofascin Stabilizes Axo-axonic GABAergic Terminals at the Axon Initial Segment
- (2011) Martin Kriebel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Novel Interaction Sites that Determine Specificity between Fibroblast Growth Factor Homologous Factors and Voltage-gated Sodium Channels
- (2011) Chaojian Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting
- (2011) Hélène Vacher et al. JOURNAL OF CELL BIOLOGY
- Short- and Long-Term Plasticity at the Axon Initial Segment
- (2011) M. S. Grubb et al. JOURNAL OF NEUROSCIENCE
- Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice
- (2011) Josiane Budni et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Large-scaleDe NovoPrediction of Physical Protein-Protein Association
- (2011) Antigoni Elefsinioti et al. MOLECULAR & CELLULAR PROTEOMICS
- Glycogen Synthase Kinase-3 Is a Functional Modulator of Serotonin-1B Receptors
- (2011) L. Chen et al. MOLECULAR PHARMACOLOGY
- A Critical Role for Neurofascin in Regulating Action Potential Initiation through Maintenance of the Axon Initial Segment
- (2011) Barbara Zonta et al. NEURON
- Review of Pharmacological Treatment in Mood Disorders and Future Directions for Drug Development
- (2011) Xiaohua Li et al. NEUROPSYCHOPHARMACOLOGY
- AKT Kinase Activity Is Required for Lithium to Modulate Mood-Related Behaviors in Mice
- (2011) Jen Q Pan et al. NEUROPSYCHOPHARMACOLOGY
- Phase I Dose Finding Studies of Obatoclax (GX15-070), a Small Molecule Pan-BCL-2 Family Antagonist, in Patients with Advanced Solid Tumors or Lymphoma
- (2010) J. J. Hwang et al. CLINICAL CANCER RESEARCH
- Homophilic Adhesion Mechanism of Neurofascin, a Member of the L1 Family of Neural Cell Adhesion Molecules
- (2010) Heli Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A βIV-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
- (2010) Thomas J. Hund et al. JOURNAL OF CLINICAL INVESTIGATION
- Activated Microglia Mediate Axoglial Disruption That Contributes to Axonal Injury in Multiple Sclerosis
- (2010) Owain W. Howell et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Phase I/II Study of AT-101 with Topotecan in Relapsed and Refractory Small Cell Lung Cancer
- (2010) Rebecca Suk Heist et al. Journal of Thoracic Oncology
- Casein kinase 2 and microtubules control axon initial segment formation
- (2010) Diana Sanchez-Ponce et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Rethinking schizophrenia
- (2010) Thomas R. Insel NATURE
- Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability
- (2010) Matthew S. Grubb et al. NATURE
- The axon initial segment and the maintenance of neuronal polarity
- (2010) Matthew N. Rasband NATURE REVIEWS NEUROSCIENCE
- Electrophysiology and beyond: Multiple roles of Na+ channel β subunits in development and disease
- (2010) Gustavo A. Patino et al. NEUROSCIENCE LETTERS
- Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders
- (2010) Chi-Tso Chiu et al. PHARMACOLOGY & THERAPEUTICS
- Efficacy and Effectiveness of Antidepressants: Current Status of Research
- (2010) H. Edmund Pigott et al. PSYCHOTHERAPY AND PSYCHOSOMATICS
- Mass spectrometry-based phosphoproteomics reveals multisite phosphorylation on mammalian brain voltage-gated sodium and potassium channels
- (2010) Je-Hyun Baek et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Dravet syndrome or genetic (generalized) epilepsy with febrile seizures plus?
- (2009) Ingrid E. Scheffer et al. BRAIN & DEVELOPMENT
- A Selective Filter for Cytoplasmic Transport at the Axon Initial Segment
- (2009) Ai-hong Song et al. CELL
- Cell-Type-Dependent Molecular Composition of the Axon Initial Segment
- (2009) A. Lorincz et al. JOURNAL OF NEUROSCIENCE
- Genome-wide association study of bipolar disorder in European American and African American individuals
- (2009) E N Smith et al. MOLECULAR PSYCHIATRY
- Distinct contributions of Nav1.6 and Nav1.2 in action potential initiation and backpropagation
- (2009) Wenqin Hu et al. NATURE NEUROSCIENCE
- Tubulin tyrosination navigates the kinesin-1 motor domain to axons
- (2009) Yoshiyuki Konishi et al. NATURE NEUROSCIENCE
- Axon Initial Segment Ca2+ Channels Influence Action Potential Generation and Timing
- (2009) Kevin J. Bender et al. NEURON
- Ischaemia differentially regulates GABAB receptor subunits in organotypic hippocampal slice cultures
- (2009) Helena Cimarosti et al. NEUROPHARMACOLOGY
- Selective Alterations in Postsynaptic Markers of Chandelier Cell Inputs to Cortical Pyramidal Neurons in Subjects with Schizophrenia
- (2009) Dianne A Cruz et al. NEUROPSYCHOPHARMACOLOGY
- Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G
- (2008) Aline Bréchet et al. JOURNAL OF CELL BIOLOGY
- Role of Axonal NaV1.6 Sodium Channels in Action Potential Initiation of CA1 Pyramidal Neurons
- (2008) Michel Royeck et al. JOURNAL OF NEUROPHYSIOLOGY
- Postsynaptic Density-93 Clusters Kv1 Channels at Axon Initial Segments Independently of Caspr2
- (2008) Y. Ogawa et al. JOURNAL OF NEUROSCIENCE
- PICK1 uncoupling from mGluR7a causes absence-like seizures
- (2008) Federica Bertaso et al. NATURE NEUROSCIENCE
- Action potential generation requires a high sodium channel density in the axon initial segment
- (2008) Maarten H P Kole et al. NATURE NEUROSCIENCE
- Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice
- (2008) Angelo O. Rosa et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Core candidate neurochemical and imaging biomarkers of Alzheimer’s disease
- (2007) Harald Hampel et al. Alzheimers & Dementia
- The fibroblast growth factor system is downregulated following social defeat
- (2007) Cortney A. Turner et al. NEUROSCIENCE LETTERS
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started