Mapping asthma-associated variants in admixed populations

The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States

(2015) Katarzyna Bryc et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ALDsuite: Dense marker MALD using principal components of ancestral linkage disequilibrium

(2015) Randall C Johnson et al.   BMC GENETICS

Admixture mapping of coronary artery calcification in African Americans from the NHLBI family heart study

(2015) Felicia Gomez et al.   BMC GENETICS

African ancestry, lung function and the effect of genetics

(2015) Ana Maria B. Menezes et al.   EUROPEAN RESPIRATORY JOURNAL

Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos

(2015) Maria Pino-Yanes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Neighborhood poverty, urban residence, race/ethnicity, and asthma: Rethinking the inner-city asthma epidemic

(2015) Corinne A. Keet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

(2015) Catherine Igartua et al.   Nature Communications

Unravelling the hidden ancestry of American admixed populations

(2015) Francesco Montinaro et al.   Nature Communications

Admixture Mapping Identifies a Quantitative Trait Locus Associated with FEV1/FVC in the COPDGene Study

(2014) Margaret M. Parker et al.   GENETIC EPIDEMIOLOGY

Trends in racial disparities for asthma outcomes among children 0 to 17 years, 2001-2010

(2014) Lara J. Akinbami et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: The Genes-environments & Admixture in Latino Americans study

(2014) Joshua M. Galanter et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Genetic Atlas of Human Admixture History

(2014) G. Hellenthal et al.   SCIENCE

Accurate Local-Ancestry Inference in Exome-Sequenced Admixed Individuals via Off-Target Sequence Reads

(2013) Youna Hu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation

(2013) Bogdan Pasaniuc et al.   BIOINFORMATICS

Distribution of ancestral chromosomal segments in admixed genomes and its implications for inferring population history and admixture mapping

(2013) Wenfei Jin et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

GeneOnEarth: Fitting Genetic PC Plots on the Globe

(2013) Sergio Torres-Sanchez et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Differences in asthma genetics between Chinese and other populations

(2013) Ting F. Leung et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A genome-wide association study of bronchodilator response in Latinos implicates rare variants

(2013) Katherine A. Drake et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pharmacogenetics: Implications of race and ethnicity on defining genetic profiles for personalized medicine

(2013) Victor E. Ortega et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Methacholine PC20 in African Americans and whites with asthma with homozygous genotypes at ADRB2 codon 16

(2013) Kathryn Blake et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Generalization and Dilution of Association Results from European GWAS in Populations of Non-European Ancestry: The PAGE Study

(2013) Christopher S. Carlson et al.   PLOS BIOLOGY

The PSEN1, p.E318G Variant Increases the Risk of Alzheimer's Disease in APOE-ε4 Carriers

(2013) Bruno A. Benitez et al.   PLoS Genetics

Visualizing genomic information across chromosomes with PhenoGram

(2013) Daniel Wolfe et al.   BioData Mining

Environmental exposures: an underrecognized contribution to noncommunicable diseases

(2013) Rosana E. Norman et al.   REVIEWS ON ENVIRONMENTAL HEALTH

African Ancestry and Genetic Risk for Uterine Leiomyomata

(2012) L. A. Wise et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Education, Genetic Ancestry, and Blood Pressure in African Americans and Whites

(2012) Amy L. Non et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Fast and accurate inference of local ancestry in Latino populations

(2012) Yael Baran et al.   BIOINFORMATICS

Whole-exome sequencing of a pedigree segregating asthma

(2012) Andrew T DeWan et al.   BMC Medical Genetics

Asthma in African Americans: What can we do about the higher rates of disease?

(2012) S. K. SILVERS et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Multiway Admixture Deconvolution Using Phased or Unphased Ancestral Panels

(2012) Claire Churchhouse et al.   GENETIC EPIDEMIOLOGY

Detecting Rare Variant Effects Using Extreme Phenotype Sampling in Sequencing Association Studies

(2012) Ian J. Barnett et al.   GENETIC EPIDEMIOLOGY

AncestrySNPminer: A bioinformatics tool to retrieve and develop ancestry informative SNP panels

(2012) Sushil Amirisetty et al.   GENOMICS

African ancestry and lung function in Puerto Rican children

(2012) John M. Brehm et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Case-control admixture mapping in Latino populations enriches for known asthma-associated genes

(2012) Dara G. Torgerson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer

(2012) Julius Gudmundsson et al.   NATURE GENETICS

Rare and common variants: twenty arguments

(2012) Greg Gibson   NATURE REVIEWS GENETICS

Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA

(2012) Adaikalavan Ramasamy et al.   PLoS One

The Greater Cincinnati Pediatric Clinic Repository: A Novel Framework for Childhood Asthma and Allergy Research

(2012) Melinda Butsch Kovacic et al.   Pediatric Allergy Immunology and Pulmonology

Inference of Population Structure using Dense Haplotype Data

(2012) Daniel John Lawson et al.   PLoS Genetics

Invited Commentary: GE-Whiz! Ratcheting Gene-Environment Studies up to the Whole Genome and the Whole Exposome

(2011) D. C. Thomas et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Enhancements to the ADMIXTURE algorithm for individual ancestry estimation

(2011) David H Alexander et al.   BMC BIOINFORMATICS

Comparison of measures of marker informativeness for ancestry and admixture mapping

(2011) Lili Ding et al.   BMC GENOMICS

Controversies regarding long-acting β2-agonists

(2011) Reena Khianey et al.   Current Opinion in Allergy and Clinical Immunology

Genetic and genomic approaches to asthma

(2011) Youming Zhang et al.   CURRENT OPINION IN PULMONARY MEDICINE

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

(2011) Lin T. Guey et al.   GENETIC EPIDEMIOLOGY

Using extreme phenotype sampling to identify the rare causal variants of quantitative traits in association studies

(2011) Dalin Li et al.   GENETIC EPIDEMIOLOGY

Low-coverage sequencing: Implications for design of complex trait association studies

(2011) Y. Li et al.   GENOME RESEARCH

Costs of asthma in the United States: 2002-2007

(2011) Sarah Beth L. Barnett et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Admixture provides new insights into recombination

(2011) Paul F O'Reilly et al.   NATURE GENETICS

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

(2011) Carole Ober et al.   NATURE GENETICS

New approaches to disease mapping in admixed populations

(2011) Michael F. Seldin et al.   NATURE REVIEWS GENETICS

Differences in Candidate Gene Association between European Ancestry and African American Asthmatic Children

(2011) Tesfaye M. Baye et al.   PLoS One

Identification of KIF3A as a Novel Candidate Gene for Childhood Asthma Using RNA Expression and Population Allelic Frequencies Differences

(2011) Melinda Butsch Kovacic et al.   PLoS One

Demographic history and rare allele sharing among human populations

(2011) S. Gravel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Joint Ancestry and Association Testing in Admixed Individuals

(2011) Daniel Shriner et al.   PLoS Computational Biology

Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project

(2011) Guillaume Lettre et al.   PLoS Genetics

Questioning the importance of genetic ancestry as a contributor to preterm delivery and related traits in African American women

(2010) Amy L. Non et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Admixture Mapping Comes of Age

(2010) Cheryl A. Winkler et al.   Annual Review of Genomics and Human Genetics

Extremes of Unexplained Variation as a Phenotype

(2010) Matthew B. Lanktree et al.   Circulation-Cardiovascular Genetics

Joint testing of genotype and ancestry association in admixed families

(2010) Hua Tang et al.   GENETIC EPIDEMIOLOGY

Molecular basis of a linkage peak: exome sequencing and family-based analysis identify a rare genetic variant in the ADIPOQ gene in the IRAS Family Study

(2010) Donald W. Bowden et al.   HUMAN MOLECULAR GENETICS

Variation across the allele frequency spectrum

(2010) Anna L Gloyn et al.   NATURE GENETICS

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

(2010) Christopher T Johansen et al.   NATURE GENETICS

Genetic Ancestry in Lung-Function Predictions

(2010) Rajesh Kumar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genotype–environment interactions and their translational implications

(2010) Tesfaye M Baye et al.   Personalized Medicine

Mapping genes that predict treatment outcome in admixed populations

(2010) T M Baye et al.   PHARMACOGENOMICS JOURNAL

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Investigation and Functional Characterization of Rare Genetic Variants in the Adipose Triglyceride Lipase in a Large Healthy Working Population

(2010) Stefan Coassin et al.   PLoS Genetics

Inference of locus-specific ancestry in closely related populations

(2009) B. Pasaniuc et al.   BIOINFORMATICS

Fast model-based estimation of ancestry in unrelated individuals

(2009) D. H. Alexander et al.   GENOME RESEARCH

A genome-wide association study on African-ancestry populations for asthma

(2009) Rasika A. Mathias et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differential Regulation of α7 Nicotinic Receptor Gene (CHRNA7) Expression in Schizophrenic Smokers

(2009) Sharon Mexal et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

Common disorders are quantitative traits

(2009) Robert Plomin et al.   NATURE REVIEWS GENETICS

Status of Childhood Asthma in the United States, 1980–2007

(2009) Lara J. Akinbami et al.   PEDIATRICS

Genetic Ancestry, Social Classification, and Racial Inequalities in Blood Pressure in Southeastern Puerto Rico

(2009) Clarence C. Gravlee et al.   PLoS One

The Genetic Structure and History of Africans and African Americans

(2009) S. A. Tishkoff et al.   SCIENCE

Sensitive Detection of Chromosomal Segments of Distinct Ancestry in Admixed Populations

(2009) Alkes L. Price et al.   PLoS Genetics

Genetic Differences between the Determinants of Lipid Profile Phenotypes in African and European Americans: The Jackson Heart Study

(2009) Rahul C. Deo et al.   PLoS Genetics

Database mining for selection of SNP markers useful in admixture mapping

(2009) Tesfaye M Baye et al.   BioData Mining

Estimating Local Ancestry in Admixed Populations

(2008) Sriram Sankararaman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The use of plasmodes as a supplement to simulations: A simple example evaluating individual admixture estimation methodologies

(2008) Laura K. Vaughan et al.   COMPUTATIONAL STATISTICS & DATA ANALYSIS

Haplotypes in SLC24A5 Gene as Ancestry Informative Markers in Different Populations

(2008) Emiliano Giardina et al.   CURRENT GENOMICS

Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region

(2008) Shweta Choudhry et al.   HUMAN GENETICS

Differences in allergic sensitization by self-reported race and genetic ancestry

(2008) James J. Yang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Principal component analysis of genetic data

(2008) David Reich et al.   NATURE GENETICS

The Marshfield Clinic Personalized Medicine Research Project: 2008 scientific update and lessons learned in the first 6 years

(2008) Catherine A McCarty et al.   Personalized Medicine

Comparison of Population-Based Association Study Methods Correcting for Population Stratification

(2008) Feng Zhang et al.   PLoS One

The Legitimacy of Genetic Ancestry Tests

(2008) T. Frudakis; et al.   SCIENCE