Article
Biology
Zhi-Kang Zhang, Xin-Cun Wang, Wen-Ying Zhuang, Xian-Hao Cheng, Peng Zhao
Summary: Talaromyces species are found worldwide, with industrial importance but also pathogenic potential. Two new Talaromyces species were discovered in southwestern China, enhancing the understanding and potential use of the genus. China plays a significant role in global biodiversity and conservation efforts.
Article
Biochemistry & Molecular Biology
Mi Zhang, Yanfang Deng, Fei Liu, Meijia Zheng, Yu Liang, Weiguang Sun, Qin Li, Xiao-Nian Li, Changxing Qi, Junjun Liu, Chunmei Chen, Hucheng Zhu, Yonghui Zhang
Summary: Five undescribed sterol derivatives were isolated from Talaromyces stipitatus, along with eight known congeners, marking the first example of this class of ergosterols from T. stipitatus. The compounds were tested for their effects on hepatoma cell lines, with two of them further evaluated for their impacts on cell cycle progression and apoptosis due to their pronounced cytotoxicity. The antiproliferative activities were mainly mediated by inducing cell apoptosis, according to the research results.
Article
Plant Sciences
Boonyanoot Chaiyosang, Kwanjai Kanokmedhakul, Kasem Soytong, Supattra Poeaim, Mayamor Soytong, Sarinya Hadsadee, Siriporn Jungsuttiwong, Jantana Yahuafai, Pongpun Siripong, Somdej Kanokmedhakul
Summary: Three new pyrrolobenzoxazine sesquiterpenoids, talatrachyoxazines A-C (1-3), were isolated from the fungus Talaromyces trachyspermus EU23, along with fourteen known compounds. Compound 1 showed cytotoxic activity against several cancer cell lines and weak antibacterial activity against both gram-positive and gram-negative bacteria. The structures and absolute configurations of the compounds were determined using spectroscopic evidence and mass spectrometry.
Article
Entomology
Wei-Jiun Lin, Ming-Chung Chiu, Chung-Chi Lin, Yuan-Kai Chung, Jui-Yu Chou
Summary: The ant pest Dolichoderus thoracicus in Taiwan has been recently found to be infected by the fungus Aspergillus nomius, which is able to penetrate the ant cuticle and spread within the colony, causing increased mortality. A. nomius was shown to be more virulent to worker ants and could potentially exploit the ant host for nutrients efficiently. Further research is needed to assess the potential impacts of utilizing A. nomius to control outbreaks of D. thoracicus, considering its potential for causing human infections and environmental consequences.
Article
Microbiology
Thuong T. T. Nguyen, Jens Christian Frisvad, Paul M. Kirk, Hyo Jin Lim, Hyang Burm Lee
Summary: Three new fungal species, Talaromyces gwangjuensis, T. koreana, and T. teleomorpha, were discovered in Korea during a study of freshwater fungi. Detailed descriptions, illustrations, and phylogenetic trees were provided based on morphological characters, multi-gene phylogenetic analysis, and extrolite data. The phylogenetic analysis showed that the three new taxa form distinct monophyletic clades.
Article
Plant Sciences
Li-Jun Huang, Xin-Ai Li, Meng-Ying Jin, Wen-Xiu Guo, Li-Rong Lei, Ran Liu, Ming-Zhi Zhang, Da-Le Guo, Dong Wang, Yan Zhou, Yun Deng, Jian-Guang Zhang
Summary: Amestolkins A and B, two previously undescribed phthalides, were isolated from Talaromyces amestolkiae. They exhibited anti-neuroinflammatory activity by inhibiting the gene expressions of proinflammatory factors and attenuating the excretion of inducible nitric oxide synthase in BV-2 microglial cells.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
(2023)
Article
Plant Sciences
Renan do Nascimento Barbosa, Jose Ewerton Felinto dos Santos, Jadson Diogo Pereira Bezerra, Lukasz Istel, Jos Houbraken, Neiva Tinti Oliveira, Cristina Maria de Souza-Motta
Summary: Understanding the geographical distribution of fungi is crucial for studying global and national fungal diversity patterns. This study provides a literature-based checklist of Aspergillus, Penicillium, and Talaromyces species in the Brazilian Atlantic Forest and Pampa biomes. The checklist highlights the limited knowledge of fungal species in tropical environments and serves as a valuable resource for future fungal biogeographical studies.
ACTA BOTANICA BRASILICA
(2022)
Article
Agronomy
Thuong T. T. Nguyen, Hyang Burm Lee
Summary: This study identified six strains from the genus Talaromyces in Korea, including five previously unrecorded species and a new species. The detailed descriptions, illustrations, and phylogenetic tree are provided.
Article
Microbiology
Vineet Meshram, Gunjan Sharma, Marcel Maymon, Alex Protasov, Zvi Mendel, Stanley Freeman
Summary: The study investigates the fungi associated with cypress bark beetles in different regions of Israel. Five distinct groups of fungi were identified, including two newly described species. The results suggest a stable association between Phloeosinus and Geosmithia species, with Talaromyces cupressi causing disease in cypress trees.
ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Infectious Diseases
Ashutosh Singh, Prerna Singh, Jacques F. Meis, Anuradha Chowdhary
Summary: Olorofim demonstrates potent in vitro activity against drug-resistant dermatophytes and opportunistic moulds, with exceptions in Alternaria alternata. When compared to other systemic antifungal drugs, Olorofim exhibits lower activity against Penicillium and Talaromyces species. Particularly, Olorofim shows strong activity against Trichophyton isolates, including those resistant to terbinafine and azoles.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Microbiology
Salilaporn Nuankaew, Charuwan Chuaseeharonnachai, Sita Preedanon, Sayanh Somrithipol, Supicha Saengkaewsuk, Papichaya Kwantong, Sarinya Phookongchai, Prasert Srikitikulchai, Noppol Kobmoo, Xin-Cun Wang, Zhi-Feng Zhang, Lei Cai, Satinee Suetrong, Nattawut Boonyuen
Summary: This study discovered two undescribed species of Talaromyces fungi in karst caves in Thailand through exploration of soil samples. The phylogenetic analysis confirmed the relationship between these new species and other Talaromyces species.
Article
Plant Sciences
Yuan-Xiang Gong, Xin Li, Li-Yuan Shi, Li Feng, Jing-Wen Wang, Ning-Hua Tan, Zhe Wang
Summary: This study isolated two new bulgarialactones from a fungus and found that one of the compounds had a cytotoxic effect on colorectal cancer cells. The researchers also elucidated the mechanism of action of this compound on cells.
PHYTOCHEMISTRY LETTERS
(2023)
Article
Environmental Sciences
Pooja Sharma, Surendra Pratap Singh, Hafiz M. N. Iqbal, Yen Wah Tong
Summary: Non-degradable pollutants resulting from industrialization, population growth, and lifestyle changes pose threats to human health and the environment. Bioremediation, utilizing microorganisms to remove hazardous contaminants, offers a cost-effective approach. Recent advancements in technologies like next-generation sequencing and metabolic profiling have provided valuable insights into microbial communities and mechanisms in environmental contaminant bioremediation.
ENVIRONMENTAL RESEARCH
(2022)
Article
Genetics & Heredity
Jiaxian Shen, Alexander G. McFarland, Vincent B. Young, Mary K. Hayden, Erica M. Hartmann
Summary: Environmental surveillance is crucial for combating public health threats like COVID-19 and antibiotic resistance. Metagenomics methods show promise but face obstacles in generating actionable interpretations. Focus on viability assessment, taxonomic resolution, quantitative metagenomics, and the use of internal standards is needed to advance the field and bring accurate monitoring to reality.
FRONTIERS IN GENETICS
(2021)
Article
Chemistry, Medicinal
Fatima P. Machado, Ines C. Rodrigues, Aikaterini Georgopolou, Luis Gales, Jose A. Pereira, Paulo M. Costa, Sharad Mistry, Salar Hafez Ghoran, Artur M. S. Silva, Tida Dethoup, Emilia Sousa, Anake Kijjoa
Summary: An undescribed hybrid phenalenone dimer, an unreported azaphilone, an unreported phthalide dimer, and an undescribed dihydroxy-ergosta-4,6,8(14)-tetraen-3-one were isolated from a marine sponge-derived fungus. The structures of these compounds were elucidated by various spectral analysis methods. Two of the isolated compounds showed significant antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureus, as well as inhibited biofilm formation.
