Efficacy and Safety of Initial Combination Therapy in Treatment-Naïve Type 2 Diabetes Patients: A Systematic Review and Meta-analysis

Initial Combination Therapy With Canagliflozin Plus Metformin Versus Each Component as Monotherapy for Drug-Naïve Type 2 Diabetes

(2016) Julio Rosenstock et al.   DIABETES CARE

Initial Combination of Empagliflozin and Metformin in Patients With Type 2 Diabetes

(2016) Samy Hadjadj et al.   DIABETES CARE

Clinical Considerations for Use of Initial Combination Therapy in Type 2 Diabetes

(2016) Avivit Cahn et al.   DIABETES CARE

8. Pharmacologic Approaches to Glycemic Treatment

(2016)   DIABETES CARE

Combination of Saxagliptin and Metformin Is Effective as Initial Therapy in New-Onset Type 2 Diabetes Mellitus With Severe Hyperglycemia

(2016) Ambika Amblee et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Randomized clinical trial of the safety and efficacy of sitagliptin and metformin co-administered to Chinese patients with type 2 diabetes mellitus

(2016) Linong Ji et al.   Journal of Diabetes Investigation

The power of two: an update on fixed-dose combinations for type 2 diabetes

(2016) Stewart B. Harris   Expert Review of Clinical Pharmacology

Efficacy and Safety of Linagliptin Co-Administered with Low-Dose Metformin Once Daily Versus High-Dose Metformin Twice Daily in Treatment-Naïve Patients with Type 2 Diabetes: a Double-Blind Randomized Trial

(2015) Linong Ji et al.   ADVANCES IN THERAPY

Initial Combination of Empagliflozin and Linagliptin in Subjects With Type 2 Diabetes

(2015) Andrew Lewin et al.   DIABETES CARE

Initial combination therapy with metformin, pioglitazone and exenatide is more effective than sequential add-on therapy in subjects with new-onset diabetes. Results from the Efficacy and Durability of Initial Combination Therapy for Type 2 Diabetes (EDICT

(2015) M. A. Abdul-Ghani et al.   DIABETES OBESITY & METABOLISM

Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes

(2015) Silvio E. Inzucchi et al.   DIABETOLOGIA

The addition of E (Empowerment and Economics) to the ABCD algorithm in diabetes care

(2015) Yeganeh Manon Khazrai et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Initial combination of linagliptin and metformin compared with linagliptin monotherapy in patients with newly diagnosed type 2 diabetes and marked hyperglycaemia: a randomized, double-blind, active-controlled, parallel group, multinational clinical trial

(2014) S. A. Ross et al.   DIABETES OBESITY & METABOLISM

Efficacy and safety of initial combination therapy with alogliptin plus metformin versus either as monotherapy in drug-naïve patients with type 2 diabetes: a randomized, double-blind, 6-month study

(2014) R. E. Pratley et al.   DIABETES OBESITY & METABOLISM

Effects of miglitol, sitagliptin, and initial combination therapy with both on plasma incretin responses to a mixed meal and visceral fat in over-weight Japanese patients with type 2 diabetes. “The MASTER randomized, controlled trial”

(2014) Atsushi Mikada et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Introduction

(2013) Alice Y.Y. Cheng   Canadian Journal of Diabetes

Efficacy and safety of dipeptidyl peptidase-4 inhibitors and metformin as initial combination therapy and as monotherapy in patients with type 2 diabetes mellitus: a meta-analysis

(2013) D. Wu et al.   DIABETES OBESITY & METABOLISM

Early combination therapy for the treatment of type 2 diabetes mellitus: systematic review and meta-analysis

(2013) O. J. Phung et al.   DIABETES OBESITY & METABOLISM

Efficacy and safety of initial combination treatment with sitagliptin and pioglitazone-a factorial study

(2013) R. R. Henry et al.   DIABETES OBESITY & METABOLISM

Combination therapy of dipeptidyl peptidase-4 inhibitors and metformin in type 2 diabetes: rationale and evidence

(2013) Y. Liu et al.   DIABETES OBESITY & METABOLISM

Concomitant use of miglitol and mitiglinide as initial combination therapy in type 2 diabetes mellitus

(2013) Fuminori Tatsumi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Adherence to Therapies in Patients with Type 2 Diabetes

(2013) Luis-Emilio García-Pérez et al.   Diabetes Therapy

Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach: Position Statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

(2012) S. E. Inzucchi et al.   DIABETES CARE

Initial combination of linagliptin and metformin improves glycaemic control in type 2 diabetes: a randomized, double-blind, placebo-controlled study

(2012) T. Haak et al.   DIABETES OBESITY & METABOLISM

Efficacy and safety of initial combination therapy with sitagliptin and pioglitazone in patients with type 2 diabetes: a 54-week study

(2012) K. H. Yoon et al.   DIABETES OBESITY & METABOLISM

Dapagliflozin, metformin XR, or both: initial pharmacotherapy for type 2 diabetes, a randomised controlled trial

(2012) R. R. Henry et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Evolution of Heterogeneity (I2) Estimates and Their 95% Confidence Intervals in Large Meta-Analyses

(2012) Kristian Thorlund et al.   PLoS One

Treatment intensification in patients with type 2 diabetes who failed metformin monotherapy

(2011) A. Z. Fu et al.   DIABETES OBESITY & METABOLISM

A randomized, parallel group, double-blind, multicentre study comparing the efficacy and safety of Avandamet (rosiglitazone/metformin) and metformin on long-term glycaemic control and bone mineral density after 80 weeks of treatment in drug-naïve type 2 d

(2011) J. L. C. Borges et al.   DIABETES OBESITY & METABOLISM

Efficacy and safety of initial combination therapy with linagliptin and pioglitazone in patients with inadequately controlled type 2 diabetes: a randomized, double-blind, placebo-controlled study

(2011) R. Gomis et al.   DIABETES OBESITY & METABOLISM

Initial therapy with the fixed-dose combination of sitagliptin and metformin results in greater improvement in glycaemic control compared with pioglitazone monotherapy in patients with type 2 diabetes

(2011) J. Wainstein et al.   DIABETES OBESITY & METABOLISM

The effect of initial therapy with the fixed-dose combination of sitagliptin and metformin compared with metformin monotherapy in patients with type 2 diabetes mellitus

(2011) C. Reasner et al.   DIABETES OBESITY & METABOLISM

Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and pioglitazone on glycemic control and measures of β-cell function in patients with type 2 diabetes

(2011) K. H. Yoon et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Initial Combination Therapy With Alogliptin and Pioglitazone in Drug-Naive Patients With Type 2 Diabetes

(2010) J. Rosenstock et al.   DIABETES CARE

Initial Combination Therapy With Metformin and Colesevelam for Achievement of Glycemic and Lipid Goals in Early Type 2 Diabetes

(2010) Julio Rosenstock et al.   Endocrine Practice

Meta-analysis of binary outcomes from two-by-two tables when the length of follow-up varies and hazards are proportional

(2010) C Combescure et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Efficacy and safety of pioglitazone/metformin fixed-dose combination therapy compared with pioglitazone and metformin monotherapy in treating patients with T2DM

(2009) Alfonso Perez et al.   CURRENT MEDICAL RESEARCH AND OPINION

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: a randomized controlled trial

(2009) M. Jadzinsky et al.   DIABETES OBESITY & METABOLISM

Vildagliptin plus metformin combination therapy provides superior glycaemic control to individual monotherapy in treatment-naive patients with type 2 diabetes mellitus

(2009) E. Bosi et al.   DIABETES OBESITY & METABOLISM

The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration

(2009) Alessandro Liberati et al.   PLOS MEDICINE

Initial treatment with fixed-dose combination rosiglitazone/glimepiride in patients with previously untreated type 2 diabetes

(2007) H. S. Chou et al.   DIABETES OBESITY & METABOLISM