Journal
ORGANIC CHEMISTRY FRONTIERS
Volume 1, Issue 4, Pages 426-429Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4qo00022f
Keywords
-
Categories
Funding
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM101389] Funding Source: NIH RePORTER
- NIGMS NIH HHS [R01 GM101389] Funding Source: Medline
Ask authors/readers for more resources
This highlight details the recent emergence of a new type of A(3) reaction (three-component condensation of an amine, an aldehyde and an alkyne). In contrast to the classic A(3) coupling process, the redox-A(3) reaction incorporates an iminium isomerization step and leads to amine alpha-alkynylation. The overall transformation is redox-neutral by virtue of a combined reductive N-alkylation/oxidative C-H bond functionalization.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
