4.7 Article

Fusarisetins: structure-function studies on a novel class of cell migration inhibitors

Journal

ORGANIC CHEMISTRY FRONTIERS
Volume 1, Issue 2, Pages 135-139

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3qo00067b

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Funding

  1. National Institutes of Health (NIH) [R01 CA133002]
  2. National Science Foundation [CHE9709183, CHE0741968]

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Herein, we report the effects of fusarisetin A on cell morphology focusing in particular on actin and microtubules dynamics. We also report the synthesis and structure-function studies of a designed library of synthetic fusarisetins in cell-based assays.

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