Journal
ORGANIC CHEMISTRY FRONTIERS
Volume 1, Issue 1, Pages 68-72Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3qo00027c
Keywords
-
Categories
Funding
- Natural Science Foundation of China [21025208, 21202171]
- National Basic Research Program of China [2011CB808600]
Ask authors/readers for more resources
We report here the first effective example of asymmetric conjugate addition-protonation reactions of azoles to vinyl ketones by chiral primary amine catalysis. High enantioselectivity can be easily achieved by screening different primary amine catalysts, and the Curtin-Hammett control in the C-N bond formation step was verified by DFT calculations to account for the observed stereoselectivity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available