Combining NK cells and mAb9.2.27 to combat NG2-dependent and anti-inflammatory signals in glioblastoma

Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival

(2015) Aurelie Poli et al.   Oncotarget

Natural killer cells in intracranial neoplasms: presence and therapeutic efficacy against brain tumours

(2013) Justyna Kmiecik et al.   JOURNAL OF NEURO-ONCOLOGY

Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level

(2013) Justyna Kmiecik et al.   JOURNAL OF NEUROIMMUNOLOGY

The natural killer cell response and tumor debulking are associated with prolonged survival in recurrent glioblastoma patients receiving dendritic cells loaded with autologous tumor lysates

(2013) Serena Pellegatta et al.   OncoImmunology

Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma

(2011) Agnete Svendsen et al.   ACTA NEUROPATHOLOGICA

NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature

(2011) M. T. F. Al-Mayhani et al.   NEURO-ONCOLOGY

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling

(2008) M Chekenya et al.   ONCOGENE