Journal
ONCOIMMUNOLOGY
Volume 3, Issue 11, Pages -Publisher
LANDES BIOSCIENCE
DOI: 10.4161/21624011.2014.965573
Keywords
malignant glioma; galectin-1; natural killer cells; innate antitumor immunity
Categories
Ask authors/readers for more resources
Natural killer (NK) cells eradicate galectin-deficient malignant gliomas without the necessity for T cell cooperation. This phenomenon was discovered as a consequence of reducing glioma-derived galectin-1. We propose that stimulation of endogenous antitumor NK cell activity may be achieved by reducing potent tumor-derived NK cell inhibitors, such as galectin-1, and that such agents be tested in the clinic to treatbrain tumors.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available