Journal
ONCOIMMUNOLOGY
Volume 3, Issue 2, Pages -Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/onci.27988
Keywords
natural killer cells; MLL5; natural cytotoxicity receptors; immunotherapy; tumor cells; NKp44; NKp44L
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We have recently identified that the ligand of natural cytotoxicity triggering receptor 2 (NCR2, best known as NKp44) is expressed on a large panel of malignant cells. This ligand provides a new tool to investigate how stressed cells are recognized and eliminated by natural killer (NK) cells, and to develop novel immunotherapeutic paradigms against cancer.
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