SOX2-specific adaptive immunity and response to immunotherapy in non-small cell lung cancer

Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer

(2013) M. Sznol et al.   CLINICAL CANCER RESEARCH

High SOX2 Levels Predict Better Outcome in Non-Small Cell Lung Carcinomas

(2013) Vamsidhar Velcheti et al.   PLoS One

Clinical Impact of Immune Microenvironment in Stage I Lung Adenocarcinoma: Tumor Interleukin-12 Receptor β2 (IL-12Rβ2), IL-7R, and Stromal FoxP3/CD3 Ratio Are Independent Predictors of Recurrence

(2012) Kei Suzuki et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

SOX2 Gene Regulates the Transcriptional Network of Oncogenes and Affects Tumorigenesis of Human Lung Cancer Cells

(2012) Si Chen et al.   PLoS One

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

(2012) J. M. Taube et al.   Science Translational Medicine

Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer

(2011) R Xiang et al.   BRITISH JOURNAL OF CANCER

Endogenous T Cell Responses to Antigens Expressed in Lung Adenocarcinomas Delay Malignant Tumor Progression

(2011) Michel DuPage et al.   CANCER CELL

Vaccines Targeting Cancer Stem Cells

(2011) Madhav V. Dhodapkar et al.   CANCER JOURNAL

SOX2 in squamous cell carcinoma: Amplifying a pleiotropic oncogene along carcinogenesis

(2011) Thomas Hussenet et al.   CELL CYCLE

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

(2011) Munehide Nakatsugawa et al.   LABORATORY INVESTIGATION

Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab

(2011) J. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progressive 3q Amplification Consistently TargetsSOX2in Preinvasive Squamous Lung Cancer

(2010) Frank McCaughan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Natural immunity to pluripotency antigen OCT4 in humans

(2010) K. M. Dhodapkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical Significance of Tumor-Infiltrating Lymphocytes in Lung Neoplasms

(2009) Enrico Ruffini et al.   ANNALS OF THORACIC SURGERY

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

(2009) Adam J Bass et al.   NATURE GENETICS

Predominant infiltration of macrophages and CD8+T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer

(2008) Osamu Kawai et al.   CANCER