Strategies to improve the immunogenicity of anticancer vaccines based on dendritic cell/malignant cell fusions

Expression of a Soluble TGF-  Receptor by Tumor Cells Enhances Dendritic Cell/Tumor Fusion Vaccine Efficacy

(2014) M. Zhang et al.   JOURNAL OF IMMUNOLOGY

Nivolumab plus Ipilimumab in Advanced Melanoma

(2013) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Combined TLR2/4-Activated Dendritic/Tumor Cell Fusions Induce Augmented Cytotoxic T Lymphocytes

(2013) Shigeo Koido et al.   PLoS One

Augmentation of Antitumor Immunity by Fusions of Ethanol-Treated Tumor Cells and Dendritic Cells Stimulated via Dual TLRs through TGF-β1 Blockade and IL-12p70 Production

(2013) Shigeo Koido et al.   PLoS One

Fusions between dendritic cells and whole tumor cells as anticancer vaccines

(2013) Shigeo Koido et al.   OncoImmunology

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting PD-1/PD-L1 interactions for cancer immunotherapy

(2012) Laurence Zitvogel et al.   OncoImmunology

Gene silencing of TGF-β1 enhances antitumor immunity induced with a dendritic cell vaccine by reducing tumor-associated regulatory T cells

(2011) Helen Conroy et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cooperative Regulation of NOTCH1 Protein-Phosphatidylinositol 3-Kinase (PI3K) Signaling by NOD1, NOD2, and TLR2 Receptors Renders Enhanced Refractoriness to Transforming Growth Factor-β (TGF-β)- or Cytotoxic T-lymphocyte Antigen 4 (CTLA-4)-mediated Impairment of Human Dendritic Cell Maturation

(2011) Devram Sampat Ghorpade et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer Vaccine by Fusions of Dendritic and Cancer Cells

(2010) Shigeo Koido et al.   Clinical & Developmental Immunology

Regulation of Tumor Immunity by Tumor/Dendritic Cell Fusions

(2010) Shigeo Koido et al.   Clinical & Developmental Immunology

Systemic Inhibition of Transforming Growth Factor-  in Glioma-Bearing Mice Improves the Therapeutic Efficacy of Glioma-Associated Antigen Peptide Vaccines

(2009) R. Ueda et al.   CLINICAL CANCER RESEARCH

Synergistic Enhancement of CD8+ T Cell-Mediated Tumor Vaccine Efficacy by an Anti-Transforming Growth Factor-  Monoclonal Antibody

(2009) M. Terabe et al.   CLINICAL CANCER RESEARCH

Cancer immunotherapy by fusions of dendritic cells and tumor cells

(2009) Shigeo Koido et al.   Immunotherapy

A Heat Shock Protein 70-Based Vaccine with Enhanced Immunogenicity for Clinical Use

(2009) Jianlin Gong et al.   JOURNAL OF IMMUNOLOGY

Paired Toll-like Receptor Agonists Enhance Vaccine Therapy through Induction of Interleukin-12

(2008) R. Zheng et al.   CANCER RESEARCH