TLR2 ligation protects effector T cells from regulatory T-cell mediated suppression and repolarizes T helper responses following MVA-based cancer immunotherapy

2011: the immune hallmarks of cancer

(2011) Federica Cavallo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IL-17 + Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer

(2011) Ilona Kryczek et al.   JOURNAL OF IMMUNOLOGY

TLR2 Stimulation Drives Human Naive and Effector Regulatory T Cells into a Th17-Like Phenotype with Reduced Suppressive Function

(2011) M. H. Nyirenda et al.   JOURNAL OF IMMUNOLOGY

TLR1/TLR2 Agonist Induces Tumor Regression by Reciprocal Modulation of Effector and Regulatory T Cells

(2011) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells

(2010) Tatiana N. Golovina et al.   CANCER JOURNAL

T regulatory cells in cancer: recent advances and therapeutic potential

(2010) Eyad Elkord et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Toll-like Receptor 2 Signaling in CD4+ T Lymphocytes Promotes T Helper 17 Responses and Regulates the Pathogenesis of Autoimmune Disease

(2010) Joseph M. Reynolds et al.   IMMUNITY

Differential but Direct Abolishment of Human Regulatory T Cell Suppressive Capacity by Various TLR2 Ligands

(2010) H. H. Oberg et al.   JOURNAL OF IMMUNOLOGY

Induction of Th17 Cells in the Tumor Microenvironment Improves Survival in a Murine Model of Pancreatic Cancer

(2010) J. L. Gnerlich et al.   JOURNAL OF IMMUNOLOGY

Clinical Use of Anti-CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells

(2009) Andrew J. Rech et al.   Annals of the New York Academy of Sciences

Plasticity of CD4+ FoxP3+ T cells

(2009) Xuyu Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Regulatory T cells and immune tolerance to tumors

(2009) Xuefang Cao   IMMUNOLOGIC RESEARCH

STAT6 Activation Confers upon T Helper Cells Resistance to Suppression by Regulatory T Cells

(2009) B. B. L. Pillemer et al.   JOURNAL OF IMMUNOLOGY

IL-6 Signaling in Psoriasis Prevents Immune Suppression by Regulatory T Cells

(2009) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

Engagement of TLR2 Does not Reverse the Suppressor Function of Mouse Regulatory T Cells, but Promotes Their Survival

(2009) Q. Chen et al.   JOURNAL OF IMMUNOLOGY

Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome

(2009) Julie Delaloye et al.   PLoS Pathogens

Tumor-specific Th17-polarized cells eradicate large established melanoma

(2008) P. Muranski et al.   BLOOD

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD

DC activated via dectin-1 convert Treg into IL-17 producers

(2008) Fabiola Osorio et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Clinical development of MVA-based therapeutic cancer vaccines

(2008) Bruce Acres et al.   Expert Review of Vaccines

Engagement of Toll-like receptor-2 on cytotoxic T-lymphocytes occurs in vivo and augments antitumor activity

(2008) Nicole Asprodites et al.   FASEB JOURNAL

Autoantibodies to tumor-associated antigens: reporters from the immune system

(2008) Eng M. Tan et al.   IMMUNOLOGICAL REVIEWS