Journal
ONCOIMMUNOLOGY
Volume 1, Issue 6, Pages 954-956Publisher
LANDES BIOSCIENCE
DOI: 10.4161/onci.20307
Keywords
melanoma; tumor-infiltrating lymphocytes; CTL; CD8(+) effector-memory; CD57
Categories
Funding
- NCRR NIH HHS [UL1 RR024148, TL1 RR024147] Funding Source: Medline
Ask authors/readers for more resources
Incomplete differentiation of CD8(+) cytotoxic T-lymphocytes (CTLs) in the tumor microenvironment is associated with cancer progression. We describe a new type of tumor-infiltrating CD8(+)CD57(+) T cell in cancer with hybrid phenotypic and functional properties of both an early effector-memory cell and a terminally-differentiated effector cell. These cells behave as incompletely-differentiated CTLs.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
