4.6 Article

The peripheral immune response and lung cancer prognosis

Journal

ONCOIMMUNOLOGY
Volume 1, Issue 8, Pages 1414-1416

Publisher

LANDES BIOSCIENCE
DOI: 10.4161/onci.21096

Keywords

lung cancer; prognosis; survival; gene expression; PBMC; T cell; myeloid; NSCLC

Funding

  1. NCI NIH HHS [P30 CA010815] Funding Source: Medline
  2. NCRR NIH HHS [S10 RR024693] Funding Source: Medline

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Attempts to refine and improve outcome predictions using tumor gene expression have been recently reported. We show that peripheral blood mononuclear cell (PBMC)-associated gene signatures can predict outcome in non- small cell lung carcinoma patients independent of demographic data or TNM staging, and that this information may persist after tumor resection.

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