Article
Engineering, Chemical
Ana-Belen Maestre-Hernandez, Juan-Jose Vicente-Lopez, Francisca Perez-Llamas, Maria-Emilia Candela-Castillo, Maria-Teresa Garcia-Conesa, Maria-Jose Frutos, Antonio Cano, Josefa Hernandez-Ruiz, Marino B. Arnao
Summary: Saffron bio-residues, generated during the production of saffron spices, contain high amounts of phenolic and flavonoid compounds with strong antioxidant potential. Different extraction conditions were applied to obtain hydrophilic and lipophilic components, and the antioxidant activity of the bioactive compounds was analyzed using the ABTS method. The variability in pH and color must be considered when using bio-residues as additives in the pharmaceutical and food industries.
Article
Agronomy
Eman A. Mohammed, Ismat G. Abdalla, Mohammed A. Alfawaz, Mohammed A. Mohammed, Salah A. Al Maiman, Magdi A. Osman, Abu ElGasim A. Yagoub, Amro B. Hassan
Summary: This study investigated the total phenolics, total flavonoids, and antioxidant activity of the aerial parts of onion, white radish, red radish, carrot, and beet. The results showed that these vegetables have high antioxidant properties, with root vegetables exhibiting particularly strong antioxidant capacity.
Article
Food Science & Technology
Davide Lanzoni, Eva Skrivanova, Raffaella Rebucci, Antonio Crotti, Antonella Baldi, Luca Marchetti, Carlotta Giromini
Summary: The growth of the world population has led to the investigation of alternative food/feed sources, with hemp-based products being considered excellent candidates due to their nutritional and functional properties. Scientific research has focused on assessing the nutritional and functional profiles of hemp-based products, such as hempseeds, flowers, and HS protein extract. The results indicate that these products have high nutritional value and exhibit significant antioxidant activity, making them suitable for use in food/feed formulations.
Review
Engineering, Chemical
Rodrigo Martins, Ana Barbosa, Barbara Advinha, Helia Sales, Rita Pontes, Joao Nunes
Summary: This article discusses the importance of green extraction techniques and their relevance in achieving sustainable goals set by the United Nations. Unconventional extraction techniques and green solvents are used to design greener extraction processes, reducing environmental impacts. Biorefineries play a major role in developing these processes, utilizing various biomass sources to create high-value products, energy, alternative fuels, and bioactive compounds.
Article
Plant Sciences
Patrick Yamen Mbopi, Hermann Didy S. Fozeng, Yves Martial M. Nguekeu, Gabin Thierry M. Bitchagno, Claude Berenger N. Ngantchouko, Maurice Ducret Awouafack, Till Opatz, Sylvere Augustin Ngouela, Hiroyuki Morita, Mathieu Tene
Summary: This study investigated the phytochemical constituents of the ethanol extract of Dicliptera verticillata and evaluated its antioxidant and antibacterial activities. Results showed moderate antioxidant activity, weak total phenolic content, and bactericidal effect against both Gram-positive and Gram-negative bacteria.
SOUTH AFRICAN JOURNAL OF BOTANY
(2021)
Article
Multidisciplinary Sciences
Emanuel L. Peter, Prakash B. Nagendrappa, Clement Olusoji Ajayi, Crispin Duncan Sesaazi
Summary: Optimal extraction conditions for polyphenols from Abelmoschus esculentus fruits were determined using Response Surface Methodology, and the extract showed promising antihyperglycemic activity in a diabetic rat model.
Article
Nutrition & Dietetics
Mona M. Ismail, Gehan M. El Zokm, Jose M. Miranda Lopez
Summary: This study aimed to estimate 19 compounds of eight brown macroalgal species from a clean Egyptian Red Sea coast. Based on the chemical composition, Polycladia myrica was the most valuable species, with high protein, lipid, and pigment contents, as well as a rich source of vitamins and antioxidants.
FRONTIERS IN NUTRITION
(2023)
Article
Biotechnology & Applied Microbiology
Marta Klimek-Szczykutowicz, Barbara Prokopiuk, Kinga Dziurka, Bozena Pawlowska, Halina Ekiert, Agnieszka Szopa
Summary: The study demonstrated that RBG light has a significant positive impact on the biomass growth and glucosinolate production of watercress, with a notable increase in total glucosinolate content. Extracts from biomass cultivated under RBG light showed a similar antioxidant potential to control cultures.
PLANT CELL TISSUE AND ORGAN CULTURE
(2022)
Article
Agronomy
Bixia Wang, Shian Shen, Jipeng Qu, Zhou Xu, Shiling Feng, Tao Chen, Chunbang Ding
Summary: In this study, an optimal extraction method was developed to maximize the phenolic and oleuropein content in Chinese olive leaves. It was found that young leaves in spring and winter had higher levels of phenolic compounds, with strong antioxidant and anticancer activities. Oleuropein showed a higher antioxidant effect compared to the phenolic extract, with potential for further development and utilization of Chinese olive leaves as a source of biological substances.
Article
Plant Sciences
Nusrat Bibi, Munir H. Shah, Nadeem Khan, Abdulrahman Al-Hashimi, Mohamed Soliman Elshikh, Akhtar Iqbal, Shakeel Ahmad, Arshad Mehmood Abbasi
Summary: The study aimed to evaluate the impact of growing conditions on total phenolic and total flavonoid contents, and in vitro antioxidant potential in different onion varieties. The results showed that the cultivation location, climatic conditions, and soil properties significantly affected the nutritional composition and antioxidant capacity of onions.
Article
Biotechnology & Applied Microbiology
Joana Assuncao, Helena M. Amaro, Graciliana Lopes, Tania Tavares, F. Xavier Malcata, A. Catarina Guedes
Summary: This study looked at the biotechnological potential of the marine cyanobacterium Synechocystis salina and its bioactive metabolites, exploring various solvent combinations to extract metabolites with antioxidant properties. Successive extractions yielded the highest extraction yield, while single extraction with ethanol showed the highest carotenoid content.
JOURNAL OF APPLIED PHYCOLOGY
(2021)
Article
Food Science & Technology
Mohammed Saeed Alkaltham, Ahmad Mohammad Salamatullah, Mehmet Musa ozcan, Nurhan Uslu, Khizar Hayat, Isam A. Mohamed Ahmed
Summary: The study demonstrated that drying processes significantly enhance the antioxidant activity and total phenolic content of myrtle fruit, especially microwave drying has a significant impact on the alteration of its chemical composition.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2021)
Article
Food Science & Technology
Dongsheng Yang, Xuan Gao
Summary: Beer is the most widely consumed fermented beverage in the world with many health benefits. The antioxidants in beer, including phenolic compounds and vitamins, play a crucial role in preventing oxidative stress and DNA damage. The optimization of brewing process controls, such as malting, mashing, and fermentation, can increase the antioxidant activities and stability of beer. Selectively adding exogenous antioxidants can improve the antioxidant properties of beer.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Food Science & Technology
Diego Morales, Roger Gutierez-Pensado, Francisca Isabel Bravo, Begona Muguerza
Summary: This study aimed to obtain alternative kombucha drinks enriched in phenolic compounds and with a high antioxidant activity using fruits instead of tea leaves. Fruit-based kombuchas prepared with different fruits and microbial consortia were evaluated for their pH, carbohydrate, ethanol, phenolic levels, and in vitro antioxidant capacity during fermentation. The results showed that fruit-based kombuchas, especially the strawberry kombucha, had higher levels of phenolic compounds and exhibited high in vitro antioxidant activity.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Food Science & Technology
Yu-Qing Zeng, Jin-Tao He, Bo-Yong Hu, Wen Li, Jing Deng, Qin-Lu Lin, Yong Fang
Summary: Virgin coconut oil (VCO) has biological functions such as antioxidant, anti-inflammatory, antibacterial, and antiviral, and has potential therapeutic effects on many chronic degenerative diseases. This review aims to investigate the antioxidant functions of phenolic compounds in VCO and discuss the mechanisms of VCO's antioxidant activity. The composition and applications of VCO are also summarized, providing a theoretical basis for further research and development of antioxidant food additives.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Alam Zeb
Summary: The review examined the different classes of polyphenolic compounds present in commonly consumed edible oils, finding that the composition of these compounds varied depending on the origin of the oil. Soybean, sunflower, olive, and brassica oils received higher attention in terms of polyphenol composition.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Biology
Saeed Ahmad, Sanaullah Khan, Alam Zeb, Syed Wadood Ali Shah, Bashir Ahmad, Ayaz Ali Khan, Waqar Ali, Nadir Zaman Khan, Ghazala Yasmin Zamani
Summary: The extract of Medicago denticulata leaves exhibited good analgesic and antiamnesic activities, validated its traditional medicinal use, but showed negligible antidiarrheal effects.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Biology
Alam Zeb, Salman Khan, Sezai Ercisli
Summary: Brassica oleracea leaves in Pakistan are a good source of important phytochemicals such as carotenoids and chlorophylls, with variations in content and antioxidant activity observed among samples from different regions. These results suggest the potential for Brassica oleracea leaves to be utilized in food and nutraceutical industries for their rich content of beneficial compounds.
Article
Environmental Sciences
Muhammad Furqan Akhtar, Muhammad Omer Mehal, Ammara Saleem, Ahmad El Askary, Mohamed M. Abdel-Daim, Fareeha Anwar, Muhammad Ayaz, Alam Zeb
Summary: The study demonstrated that treatment with Prosopis cineraria ethanolic extract (PCDE) effectively prevented paraquat-induced toxicity in prepubertal mice by reducing oxidative stress levels and improving neurotransmitter levels in the brain. The high amount of quercetin, kaempferol, and ellagic acid derivatives in PCDE contributed to its beneficial effects on muscle and neural functions in mice exposed to paraquat.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Medicinal
Sayyed Ibrahim Shah, Fazli Nasir, Nadia Shamshad Malik, Muhammad Alamzeb, Muhammad Abbas, Inayat Ur Rehman, Fazli Khuda, Yasir Shah, Khang Weh Goh, Alam Zeb, Long Chiau Ming
Summary: This study tested the antileishmanial activity of two compounds and found that 10-hydroxy chondrofoline exhibited potent activity both in vitro and in vivo, reducing lesion size in infected mice significantly.
Article
Biotechnology & Applied Microbiology
Dil Naz, Alam Zeb, Nausheen Nazir, Rehan Ullah, Aziz ur Rahman, Ali Muhammad
Summary: This study provides scientific evidence for the hepatoprotective and nephroprotective potentials of Sedum adenotrichum in paracetamol-induced toxicity in rabbits. The methanolic extract of SA showed curative effects in mitigating paracetamol-induced toxicity in rabbits, as evidenced by changes in biochemical and hematological parameters, body weight, and histological studies of the liver and kidneys. The protective effect was attributed to the presence of bioactive phenolic compounds in the methanolic extract of SA.
Article
Food Science & Technology
Arif Mehmood, Alam Zeb
Summary: Leafy vegetables like spinach contain various health-promoting compounds that can be affected by different cooking techniques. This study investigated how boiling, frying, microwaving, thawing, and sonication affect the composition of carotenoids and other bioactive compounds in spinach leaves. The results showed that the carotenoid content in spinach was influenced by the different treatment methods, with boiling and microwave heating leading to an increase in certain carotenoids, while frying had a negative effect. Treated samples also showed variations in phenolic, flavonoid, anthocyanin contents, and DPPH scavenging activity, with frying, thawing, microwave, and sonication treatments showing different levels of retention.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Article
Multidisciplinary Sciences
Arif Mehmood, Alam Zeb, Muhammad Khalil Ateeq
Summary: The antidiabetic effects of spinach, mustard, and cabbage were studied by feeding their phenolic-rich aqueous extracts to diabetic mice. Results showed significant improvements in various biochemical and hematological indices as well as tissue histology in the treated mice. Cabbage extract was found to be the most effective in ameliorating diabetic stress among the studied vegetables.
Article
Endocrinology & Metabolism
Moonis Shoaib, Ammara Saleem, Alam Zeb, Muhammad Imran Khan, Muhammad Furqan Akhtar
Summary: This study evaluated the therapeutic effect of Centratherum anthelminticum seed extract (CA) against polycystic ovary syndrome (PCOS) in rats. The results showed that CA effectively reduced cholesterol and triglyceride levels, normalized hormone levels, improved insulin resistance, reduced inflammation, and enhanced antioxidant activity. Histopathological examination also revealed a normal follicular development in CA-treated rats. Overall, CA demonstrated antidiabetic, anti-inflammatory, antihyperlipidemic, and antioxidant properties in treating PCOS.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Arif Mehmood, Alam Zeb
Summary: Different processing treatments have been found to affect the contents of carotenoids and polyphenols in mustard leaves. Boiling treatment significantly increases the content of certain compounds, while frying has detrimental effects. Blanching and sonication treatments show the highest impact on total flavonoid content and antioxidant potential, respectively.
Article
Integrative & Complementary Medicine
Mater H. Mahnashi, Yahya S. Alqahtani, Bandar A. Alyami, Ali O. Alqarni, Sultan A. Alqahl, Farhat Ullah, Abdul Sadiq, Alam Zeb, Mehreen Ghufran, Alexey Kuraev, Asif Nawaz, Muhammad Ayaz
Summary: This study analyzed phenolics in P. hydropiepr L extracts via HPLC-DAD analysis and assessed their anti-diabetic potentials. The results showed that the plant extracts are rich in phenolic compounds, which exhibit significant inhibitory effects on α-glucosidase and α-amylase.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2022)
Article
Pharmacology & Pharmacy
Bashir Ahmad, Ali Muhammad Yousafzai, Alam Zeb, Waqar Ali, Nadir Zaman Khan, Muhammad Aasim, Saeed Ahmad, Shariat Ullah, Ayaz Ali Khan, Farhat Naz, Sumayya Raziq
Summary: The study demonstrates the hepatoprotective and antioxidative effects of TEAQ leaf extract on PCM intoxicated rabbits, with significant reduction of serum biochemical and hematological levels towards normal values. The histological analysis further supports the hepatoprotective activity of the extract, indicating its potential therapeutic value in liver protection.
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Biology
Saeed Ahmad, Sanaullah Khan, Alam Zeb, Bashir Ahmad, Ayaz Ali Khan, Waqar Ali
Summary: The study aimed to determine the antibacterial properties of Medicago denticulata against bacteria isolated from poultry litter. The results showed that the plant extract had potent antibacterial activity against resistant bacteria, particularly multi drug resistant strains. These findings suggest that active components of the plant could be isolated and further studied for antibacterial potency.
BIOSCIENCE RESEARCH
(2021)
Article
Parasitology
B. Ahmad, A. M. Yousafzai, A. Zeb, A. A. Khan, M. Attaullah, S. Ahmad
Summary: The study evaluated the antibacterial effects of Typha elephantina extracts against clinical pathogens, showing that TE.ME exhibited the highest potential in inhibiting Pseudomonas aeruginosa. In a chick model, TE.ME significantly restored damages caused by infections, suggesting its potential as a new natural antibacterial agent.
TROPICAL BIOMEDICINE
(2021)
Article
Multidisciplinary Sciences
Muhammad Zahoor, Irfan Khan, Alam Zeb, Muhammad Umar Khayam Sahibzada, Sumaira Naz, Wasim Ul Bari, Abdul Wahid Kamran
Summary: This study extracted bioactive compounds from Ziziphus oxyphylla roots and isolated three compounds, with compound V showing strong antioxidant and anticholinesterase activities. The research provides scientific evidence for the potential of Z. oxyphylla as a treatment for oxidative stress and dementia.
