Article
Cardiac & Cardiovascular Systems
Satyam Sarma, Erin Howden, Justin Lawley, Mitchel Samels, Benjamin D. Levine
Summary: Patients with HFpEF have lower peak oxygen consumption and heart rate compared to senior controls, but there were no significant differences in peak heart rate response during static handgrip exercise and metaboreceptor function between the two groups. The key reflex autonomic pathways regulating exercise heart rate responsiveness are intact in HFpEF despite lower peak exercise heart rates.
Article
Physiology
William N. Morley, Alexandra M. Coates, Jamie F. Burr
Summary: The study found that RIPC may affect heart rate acutely by reducing cardiac sympathetic activity, while RIPC(aug) reduces HRV through cardiac vagal withdrawal or increased cardiac sympathetic modulation, with effects persisting until the following morning.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Medicine, General & Internal
Robert S. Zhang, Thomas C. Hanff, Yuhui Zhang, Michael V. Genuardi, Carli J. Peters, Allison Levin, Maria Molina, Rhondalyn C. McLean, Jeremy A. Mazurek, Payman Zamani, Monique S. Tanna, Joyce Wald, Pasquale Santangeli, Pavan Atluri, Lee R. Goldberg, Edo Y. Birati
Summary: The relationship between post-transplant heart rate response (HRR) and survival is examined. A low HRR is associated with increased mortality and decreased exercise capacity in heart transplant patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Oliver Schumacher, Lukas D. Trachsel, David Herzig, Paul Mohacsi, Vilborg Sigurdardottir, Matthias Wilhelm, Prisca Eser
Summary: Younger heart transplantation recipients are more likely to show signs of cardiac reinnervation, while maximal oxygen consumption is independent of heart rate kinetics.
Article
Multidisciplinary Sciences
David M. Presby, Summer R. Jasinski, Emily R. Capodilupo
Summary: Stress can contribute to the progression of diseases, but there are few methods for continuously measuring stress. This study investigated if wearable devices can be used to measure stress by analyzing cardiovascular signals. The results showed that heart rate and heart rate variability changed after running or high-stress work, indicating that wearables can quantify stressful events and help individuals manage stress.
Review
Cardiac & Cardiovascular Systems
Sudhir Kurl, Sae Young Jae, Ari Voutilainen, Magnus Hagnas, Jari A. Laukkanen
Summary: The study found that delayed exercise heart rate reserve and slow heart rate recovery predicted the risk of SCD in the general male population, with each unit increment decreasing the incidence of SCD by 1-2%.
PROGRESS IN CARDIOVASCULAR DISEASES
(2021)
Article
Chemistry, Analytical
Jose M. Muyor, Jose A. Antequera-Vique, Jose M. Oliva-Lozano, Francisco M. Arrabal-Campos
Summary: This study analyzed the spinal morphology and core muscle activity of cyclists in both standing and cycling postures, revealing differences in the shape of the lumbar spine and anterior tilt of the sacrum between the two positions. Additionally, certain muscles showed significantly increased activation during cycling compared to standing, despite relatively low values.
Article
Chemistry, Multidisciplinary
Hung-Kai Chen, Fueng-Ho Chen, Shien-Fong Lin
Summary: The study developed an AI model to construct a guided exercise prescription system for sub-healthy groups, which achieved high testing accuracy and low mean absolute error in predicting heart rate differences after following the suggested exercise modes. The system provides quantitative exercise prescriptions to guide the sub-healthy group to engage in effective exercise programs.
APPLIED SCIENCES-BASEL
(2021)
Article
Multidisciplinary Sciences
Denise Cardoso Ribeiro Papa, Lilian Del Ciello de Menezes, Ibis Ariana Pena, Ana Clara Silveira, Natalia Padula, Suellen de Oliveira Veronez Silva, Roberta Caveiro Gaspar, Eduardo Dati Dias, Celso Ferreira, Luciano Vieira de Araujo, Todd A. Astorino, Helen Dawes, Carlos Bandeira de Mello Monteiro, Talita Dias da Silva
Summary: The purpose of this study was to analyze cardiac autonomic modulation in individuals with SCI during postural transition from sitting to orthostatism position using a cognitive VR task. The results showed that there was better sympathovagal balance between sitting and 90 degrees positions in the SCI group who performed the VR task.
Article
Sport Sciences
Lucrezia Zuccarelli, Alessandro Sartorio, Roberta De Micheli, Gabriella Tringali, Bruno Grassi
Summary: In obese patients, a 3-week multidisciplinary body mass reduction intervention increased exercise tolerance by eliminating or reducing the slow component of heart rate kinetics, facilitating exercise prescription by translating a fixed submaximal heart rate value into a work rate slightly above gas exchange threshold.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2021)
Article
Cardiac & Cardiovascular Systems
Vitor Rossi de Almeida, Thatiane Lopes Valentim di Paschoale Ostolin, Barbara de Barros Gonze, Flavio Rossi de Almeida, Marcello Romiti, Rodolfo Leite Arantes, Victor Zuniga Dourado
Summary: The early flattening of oxygen pulse is common in asymptomatic adults, and is highly determined by modifiable cardiovascular risk factors. Female sex, lower education, dyslipidemia, smoking, and physical inactivity were identified as the leading independent predictors of the early flattening of oxygen pulse through multinomial multiple logistic regression analysis.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Computer Science, Interdisciplinary Applications
M. Moya-Ramon, M. Mateo-March, I. Pena-Gonzalez, M. Zabala, A. Javaloyes
Summary: The validity and reliability of short and ultra-short HRV measurements in elite cyclists were assessed using different smartphone applications. Both Elite HRV and Welltory showed good correlation with electrocardiogram measurements and can be implemented to monitor HRV. There were no differences between short and ultra-short measurement lengths.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Pharmacology & Pharmacy
Elisabetta Zampogna, Nicolino Ambrosino, Federico Mattia Oliva, Monica Rudi, Giovanni Sotgiu, Laura Saderi, Antonio Spanevello, Dina Visca
Summary: This study evaluated the impact of pulmonary rehabilitation on heart rate recovery (HRR) in individuals with asthma compared to those with COPD. The findings showed that individuals with asthma had a lower prevalence of slow HRR than those with COPD. However, exercise training significantly improved exercise capacity in both populations.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Valmiki Maharaj, Arianne C. Agdamag, Sue Duval, Jonathan Edmiston, Victoria Charpentier, Meg Fraser, Alexandra Hall, Jessica Schultz, Ranjit John, Andrew Shaffer, Cindy M. Martin, Thenappan Thenappan, Gary S. Francis, Rebecca Cogswell, Tamas Alexy
Summary: This study aims to determine the effect of hypotensive systolic blood pressure (SBP) response during clinical outcomes among patients who underwent LVAD implantation. The results show that hypotensive SBP response is associated with increased perioperative and 90-day mortality after LVAD implantation.
Article
Physiology
Hao Wang, Xiaolin Gao, Yongjin Shi, Dongzhe Wu, Chuangtao Li, Wendi Wang
Summary: This study investigated the effects of different trunk postures on the cardiovascular and autonomic nervous systems. The results showed that deviations from a neutral trunk position can lead to changes in cardiac function, including decreased stroke volume, increased heart rate, and relative activation of sympathetic tone.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Gastroenterology & Hepatology
Neal Shahidi, Sergei Vosko, Sunil Gupta, Anthony Whitfield, Oliver Cronin, Timothy O'Sullivan, W. Arnout van Hattem, Mayenaaz Sidhu, David J. Tate, Eric Y. T. Lee, Nicholas Burgess, Stephen J. Williams, Michael J. Bourke
Summary: A selective resection algorithm (SRA) for large rectal polyps improves oncologic outcomes and reduces the risk of piecemeal resection of cancers.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Review
Immunology
Yashutosh Joshi, Sarah Scheuer, Hong Chew, Min Ru Qiu, Claudio Soto, Jeanette Villanueva, Ling Gao, Aoife Doyle, Shingo Takahara, Charles Jenkinson, Nikunj Vaidhya, Yorihiko Matsumoto, Bridget Hwang, Christine Zhao, Arjun Iyer, Mark Connellan, Alasdair Watson, Emily Granger, Kavitha Muthiah, Andrew Jabbour, Eugene Kotlyar, Anne Keogh, Nicole K. Bart, Chris Hayward, Kumud Dhital, Paul Jansz, Peter S. Macdonald
Summary: This report reviews the clinical heart transplant program at St Vincent's Hospital Sydney over 8 years and highlights the positive impact of changes in retrieval protocols for heart transplants from DCD donors. The study shows a significant reduction in severe primary graft dysfunction and comparable survival rates between DCD and brain death donation recipients.
Article
Gastroenterology & Hepatology
Hunter Wang, Mayenaaz Sidhu, Sunil Gupta, Oliver Cronin, Timothy O'Sullivan, Anthony Whitfield, Nicholas G. Burgess, Michael J. Bourke
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Transplantation
Sumita Barua, Tao Yang, Sean Conte, Christopher Bragg, Jacob Sevastos, Peter S. Macdonald, Kavitha Muthiah, Christopher S. Hayward
Summary: This study evaluated the ability of renal histology to predict adverse kidney events before and after heart transplantation. The study found that the chronicity score of renal histology was associated with adverse kidney events before transplantation and has potential utility in considering simultaneous heart-kidney transplantation.
TRANSPLANTATION DIRECT
(2023)
Article
Gastroenterology & Hepatology
Timothy O'Sullivan, David Tate, Mayenaaz Sidhu, Sunil Gupta, James Elhindi, Karen Byth, Oliver Cronin, Anthony Whitfield, Ana Craciun, Rajvinder Singh, Gregor Brown, Spiro Raftopoulos, Luke Hourigan, Alan Moss, Amir Klein, Steven Heitman, Stephen Williams, Eric Lee, Nicholas G. Burgess, Michael J. Bourke
Summary: This study investigated the relationship between large nonpedunculated colorectal polyps (LNPCPs) and synchronous colonic LNPCPs, revealing that 6.9% of LNPCPs had synchronous lesions with a greater than 4-fold increased risk for non-granular LNPCPs.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Editorial Material
Gastroenterology & Hepatology
Sunil Gupta, Anthony Whitfield, Andrew Tang, Eric Y. T. Lee, Stephen J. Williams, Nicholas G. Burgess, Michael J. Bourke
Article
Gastroenterology & Hepatology
Sunil Gupta, Sergei Vosko, Neal Shahidi, Timothy O'Sullivan, Oliver Cronin, Anthony Whitfield, Rajiv Kurup, Mayenaaz Sidhu, Eric Y. T. Lee, Stephen J. Williams, Nicholas G. Burgess, Michael J. Bourke
Summary: This study investigated the prevalence, risk factors, and management of colorectal strictures following endoscopic resection of large nonpedunculated colorectal polyps. The results showed that most patients with an endoscopic resection (ER) defect size of 90% or greater developed strictures, with a significant proportion being severe and requiring early balloon dilation. In contrast, the risk of strictures was low for ER defects of 60%-89% and less than 60%.
Article
Cardiac & Cardiovascular Systems
Marina Wassif, Phillip Lo, Paul Satouris, Lucinda Swan, Daniel Tardo, Jason C. Kovacic, David Muller, Kavitha Muthiah, Eugene Kotlyar, Nicole K. Bart
Summary: This retrospective analysis examined patients with suspected COVID-19 vaccine-related myocarditis and pericarditis presenting at St Vincent's Hospital in Sydney, Australia. The results showed that the average age of onset in the vaccine group was 3369.0 years, and the most common symptom was chest pain. 80% of patients had abnormal electrocardiogram findings, and 50% had cardiac monitoring for more than 24 hours. Cardiac complications were rare, mild, and self-limiting, with a good response to oral anti-inflammatories.
HEART LUNG AND CIRCULATION
(2023)
Article
Health Care Sciences & Services
Nicole K. Bart, Sam Emmanuel, Rodrigo Friits-Lamora, Emily Larkins, Eugene Kotlyar, Kavitha Muthiah, Andrew Jabbour, Christopher Hayward, Paul C. Jansz, Anne M. Keogh, Emma Thomas, Peter S. Macdonald
Summary: In the context of the COVID-19 pandemic, telehealth services were rapidly implemented to reduce disease transmission among vulnerable heart transplant recipients. A cohort study showed that telehealth consultations significantly reduced patient travel and wait times, without an apparent increase in re-hospitalization or mortality. In summary, telehealth was found to be feasible and preferred in heart transplant recipients, with higher acuity patients still requiring in-person consultations.
JOURNAL OF TELEMEDICINE AND TELECARE
(2023)
Article
Immunology
Nicole K. Bart, Sara L. Hungerford, Mayooran Namasivayam, Emily Granger, Mark Conellan, Eugene Kotlyar, Kavitha Muthiah, Andrew Jabbour, Christopher Hayward, Paul C. Jansz, Anne M. Keogh, Peter S. Macdonald
Summary: The aim of this study was to identify the causes of progression to moderate-severe tricuspid regurgitation (TR) in the first 2 years after heart transplantation. The study found that TR is more likely to be the result of underlying graft dysfunction rather than the cause of it.
Article
Medicine, General & Internal
Lisa Mary Raven, Christopher A. Muir, Cassia Kessler Iglesias, Nicole K. Bart, Kavitha Muthiah, Eugene Kotlyar, Peter Macdonald, Christopher S. Hayward, Andrew Jabbour, Jerry R. Greenfield
Summary: Cardiac transplantation is a life-saving surgery, but immunosuppression medication can lead to adverse effects. SGLT2 inhibitors have shown benefits in cardiovascular and renal outcomes for patients with type 2 diabetes and heart failure. This study aims to evaluate the safety and efficacy of SGLT2 inhibitors in cardiac transplant recipients.
Article
Gastroenterology & Hepatology
Timothy O'Sullivan, Mayenaaz Sidhu, Sunil Gupta, Karen Byth, James Elhindi, David Tate, Oliver Cronin, Anthony Whitfield, Hunter Wang, Eric Lee, Stephen Williams, Nicholas G. Burgess, Michael J. Bourke
Summary: The study aimed to develop an EMR Case Selection Score (EMR-CSS) to help inexperienced endoscopists choose appropriate cases for EMR training. The results showed that lesion size, location, and morphology predicted the success of EMR. A six-point score with a cutoff value of 2 demonstrated 81% sensitivity in both the training and validation cohorts.
Article
Gastroenterology & Hepatology
Oliver Cronin, Sunil Gupta, Julia Gauci, Anthony Whitfield, Timothy O'Sullivan, Muhammad Abuarisha, Hunter Wang, Eric Yong Tat Lee, Stephen J. Williams, Nicholas Graeme Burgess, Michael J. Bourke
Summary: Large adenomatous anastomotic polyps (LAAPs) represent a rare condition with limited data on prevalence and characteristics. This study demonstrated that LAAPs can be safely and effectively managed through endoscopic resection without recurrence at follow-up.
Article
Gastroenterology & Hepatology
Julia L. Gauci, Sunil Gupta, Muhammad Abu Arisha, Andrew Tang, Timothy OSullivan, Anthony Whitfield, Oliver Cronin, Varan Perananthan, Clarence Kerrison, Eric Y. Lee, Nicholas G. Burgess, Michael J. Bourke
Summary: Direct diverticular peroral endoscopic myotomy (DD-POEM) is a safe and effective technique for the management of thoracic esophageal diverticula. It simplifies the procedure and achieves excellent outcomes. Further evaluation is warranted to explore its potential in treating this disorder.
Article
Medicine, General & Internal
Joao Santos-Antunes, Mathieu Pioche, Felipe Ramos-Zabala, Paolo Cecinato, Francisco Gallego, Pedro Barreiro, Andre Mascarenhas, Sandro Sferrazza, Frieder Berr, Andrej Wagner, Arnaud Lemmers, Mariana Figueiredo Ferreira, Eduardo Albeniz, Hugo Uchima, Ricardo Kuttner-Magalhaes, Carlos Fernandes, Rui Morais, Sunil Gupta, Daniel Martinho-Dias, Isabel Faria-Ramos, Margarida Marques, Michael J. Bourke, Guilherme Macedo
Summary: A retrospective multicenter analysis was conducted to assess the rate of residual lesion after a piecemeal ESD resection or after an en bloc resection but with positive horizontal margins for colorectal benign neoplasia. The results showed a higher rate of residual lesion after a piecemeal ESD resection, but not after an en bloc resection with positive horizontal margins.
JOURNAL OF CLINICAL MEDICINE
(2023)