Aerosol Delivery of DNA/Liposomes to the Lung for Cystic Fibrosis Gene Therapy

Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung

(2013) E W F W Alton et al.   GENE THERAPY

A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis: Table 1

(2013) Eric W F W Alton et al.   THORAX

The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes

(2012) Lee A. Davies et al.   BIOMATERIALS

Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung

(2011) G McLachlan et al.   GENE THERAPY

Validation of recombinant Sendai virus in a non-natural host model

(2010) U Griesenbach et al.   GENE THERAPY

New Aerosol Delivery Devices for Cystic Fibrosis

(2010) Kenneth C Kesser et al.   Respiratory Care

Gene transfer to the lung: Lessons learned from more than 2 decades of CF gene therapy

(2008) Uta Griesenbach et al.   ADVANCED DRUG DELIVERY REVIEWS

Enhanced Lung Gene Expression After Aerosol Delivery of Concentrated pDNA/PEI Complexes

(2008) Lee A Davies et al.   MOLECULAR THERAPY

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression

(2008) Stephen C Hyde et al.   NATURE BIOTECHNOLOGY

The science of aerosol delivery in cystic fibrosis

(2008) David E. Geller   PEDIATRIC PULMONOLOGY