Zinc/CaMK II Associated-Mitophagy Signaling Contributed to Hippocampal Mossy Fiber Sprouting and Cognitive Deficits Following Neonatal Seizures and Its Regulation by Chronic Leptin Treatment

Leptin treatment prevents long-term abnormalities in cognition, seizure threshold, hippocampal mossy fiber sprouting and ZnT3/CB-D28k expression in a rat developmental “twist” seizure model

(2018) Hong Ni et al.   EPILEPSY RESEARCH

Long-Term Effects of Ketogenic Diet on Subsequent Seizure-Induced Brain Injury During Early Adulthood: Relationship of Seizure Thresholds to Zinc Transporter-Related Gene Expressions

(2016) Tian Tian et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Connexins: substrates and regulators of autophagy

(2016) Jegan Iyyathurai et al.   BMC CELL BIOLOGY

SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway

(2016) Zhao Jing et al.   CANCER LETTERS

A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin

(2016) Yasaman Malekizadeh et al.   CEREBRAL CORTEX

Ketogenic diet change cPLA2/clusterin and autophagy related gene expression and correlate with cognitive deficits and hippocampal MFs sprouting following neonatal seizures

(2016) Hong Ni et al.   EPILEPSY RESEARCH

Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

(2016) Caixia Guo et al.   International Journal of Nanomedicine

Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease

(2016) T.L. Platt et al.   NEUROSCIENCE

Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes

(2016) Junjie Gao et al.   Oncotarget

The Effects of Leptin Replacement on Neural Plasticity

(2016) Gilberto J. Paz-Filho   NEURAL PLASTICITY

Neurobehavioral Deficits in a Rat Model of Recurrent Neonatal Seizures Are Prevented by a Ketogenic Diet and Correlate with Hippocampal Zinc/Lipid Transporter Signals

(2015) Tian Tian et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Spatiotemporal differences in the c-fos pathway between C57BL/6J and DBA/2J mice following flurothyl-induced seizures: A dissociation of hippocampal Fos from seizure activity

(2015) Sridhar B. Kadiyala et al.   EPILEPSY RESEARCH

Structure, production and signaling of leptin

(2015) Heike Münzberg et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Long Term Hippocampal and Cortical Changes Induced by Maternal Deprivation and Neonatal Leptin Treatment in Male and Female Rats

(2015) Virginia Mela et al.   PLoS One

Inhibition of the Connexin 43 Elevation May be Involved in the Neuroprotective Activity of Leptin Against Brain Ischemic Injury

(2014) Zi-Hui Deng et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Metals and cholesterol: two sides of the same coin in Alzheimer’s disease pathology

(2014) Bruce X. Wong et al.   Frontiers in Aging Neuroscience

Leptin Attenuates Cerebral Ischemia Injury through the Promotion of Energy Metabolism via the PI3K/Akt Pathway

(2013) Jinying Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocytic p-connexin 43 regulates neuronal autophagy in the hippocampus following traumatic brain injury in rats

(2013) LI-QIAN SUN et al.   Molecular Medicine Reports

Leptin regulation of hippocampal synaptic function in health and disease

(2013) A. J. Irving et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Protective Role of Astrocytic Leptin Signaling Against Excitotoxicity

(2012) Bhavaani Jayaram et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus

(2012) Hong Ni et al.   TOXICOLOGY LETTERS

Long-term Effects of Recurrent Neonatal Seizures on Neurobehavioral Function and Related Gene Expression and Its Intervention by Inhibitor of Cathepsin B

(2011) Hong Ni et al.   NEUROCHEMICAL RESEARCH

Neuroprotective effects of leptin following kainic acid-induced status epilepticus

(2010) Makram Obeid et al.   EPILEPSY & BEHAVIOR

Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease

(2010) Tapio Nuutinen et al.   NEUROSCIENCE LETTERS

Regulation of glutamate receptor trafficking by leptin

(2009) Peter R. Moult et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A Novel Protein Complex in Membrane Rafts Linking the NR2B Glutamate Receptor and Autophagy Is Disrupted following Traumatic Brain Injury

(2009) Gregory E. Bigford et al.   JOURNAL OF NEUROTRAUMA

Leptin signaling in brain: A link between nutrition and cognition?

(2008) Christopher D. Morrison   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Increased severity of pentylenetetrazol induced seizures in leptin deficient ob/ob mice

(2008) Ebru Erbayat-Altay et al.   NEUROSCIENCE LETTERS

Anticonvulsant effects of leptin in epilepsy

(2007) Sabrina Diano et al.   JOURNAL OF CLINICAL INVESTIGATION

Leptin inhibits 4-aminopyridine– and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents

(2007) Lin Xu et al.   JOURNAL OF CLINICAL INVESTIGATION